Clinical trials
Acute Respiratory Failure clinical trials
Below are recruiting acute respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07317050RecruitingPhase 3
Aprotinin for acute respiratory distress syndrome
This trial tests a drug called aprotinin for people with moderate to severe ARDS who are on a breathing machine. The goal is to see if it helps treat the lung injury.
Ciudad Real, Ciudad RealAges 18 years+ - NCT06092437Recruiting
Testing a personalized diuretic plan for acute heart failure
This trial is testing whether a diuretic (water pill) dose tailored to each patient works better for treating fluid buildup during a heart failure flare-up. It may help you get the right amount of medication faster and avoid complications.
Heerlen, LimburgAges 18 years+ - NCT05947955RecruitingPhase 2
Study drug for infection-related lung failure in adults
This Phase 2 trial tests Rhu-pGSN in adults with acute respiratory distress syndrome (ARDS) caused by an infection. If you qualify, the study may help determine whether the drug improves outcomes in this short-term, life-threatening lung condition.
Los Angeles, CaliforniaAges 18 years+ - NCT07203781Recruiting
Breathing machine settings and their effect on breathing effort
This study is testing how different settings on a breathing machine affect your breathing effort and drive. It may help doctors find the best ventilator settings for patients with severe low oxygen levels.
Nijmegen, GelderlandAges 18 years+ - NCT07366541Recruiting
Predicting oxygen therapy failure using a monitoring device
This study tests a monitoring device to predict if a patient with low oxygen levels will need a breathing tube within 72 hours. It aims to help doctors decide earlier if a patient needs more intensive support.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07517497Recruiting
Lung Vibration Device for Seniors With Hip Fracture and Breathing Problems
This study tests a special vibration device on the chest to help older adults who have both a hip fracture and acute breathing failure recover better. The device uses gentle vibrations to help clear the lungs and improve breathing.
AstanaAges 60–85 - NCT07324980Recruiting
Ultrasound for breathing trouble in the ER
This study tests if a quick ultrasound can help doctors figure out why you are having trouble breathing when you come to the emergency room. It may lead to faster and more accurate care.
NovaraAges 18 years+ - NCT05689476Recruiting
Measuring diaphragm breathing signals during ICU ventilation
This study measures electrical activity of the diaphragm and how your breathing system works while you are on a breathing machine in the ICU. It may help doctors better understand breathing during recovery after major lung events.
Padova, ItalyAges 18 years+ - NCT05108896Recruiting
Testing breathing and swallowing recovery after ICU breathing support
This study looks at aspiration (food or liquid going “the wrong way” into the airway) in people who survived a serious ICU breathing problem. It may help doctors better support safe swallowing and breathing recovery after being on a breathing machine.
Stanford, CaliforniaAges 18 years+ - NCT07536984Enrolling by invitation
Personalized Oxygen Levels for Breathing Machine Patients
This study tests whether adjusting oxygen levels on a breathing machine (ventilator) to match each patient's individual needs improves outcomes. Doctors will carefully monitor your oxygen levels and see how different targets affect your recovery.
Nashville, TennesseeAges 18 years+ - NCT07532811Recruiting
How Lungs Distribute Air and Blood in Critically Ill Children
This pilot study uses a special belt around the chest to measure how air and blood are distributed in the lungs of children on breathing machines in the intensive care unit. The goal is to better understand lung function in critically ill children.
Bron, FranceAges Up to 12 years - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT06855004Recruiting
Study of severe breathing problems in people with lung scarring
This study follows patients with chronic lung scarring (fibrosing interstitial lung disease) who are in the intensive care unit for severe breathing failure. It aims to better understand their condition and care, which may help improve future treatments.
BobignyAges 18 years+ - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07223762Enrolling by invitation
Comparing two types of laryngoscope blades for intubation
This trial compares two types of laryngoscope blades (the tool used to guide a breathing tube) to see which works better for routine intubations. If you are an adult scheduled for a planned breathing tube placement, you may be able to join.
Birmingham, AlabamaAges 18 years+ - NCT04666246Recruiting
Studying breathing effort in people with COVID-19 breathing failure
This study looks at how hard people with COVID-19 are working to breathe when they have serious breathing trouble but are not yet fully on a breathing machine. The results may help doctors better understand breathing support needs and improve care.
ModenaAges 18–80 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT06996834Recruiting
Comparing breathing support methods for pneumonia-related breathing failure
This trial tests two noninvasive breathing support methods (NIV and HVNI) for people with pneumonia who are having trouble breathing. The goal is to see which method works better to help you avoid needing a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06934876Recruiting
Comparing two CO2 detectors during breathing tube placement in critically ill adults
This study compares two ways of checking that a breathing tube is placed correctly in seriously ill adults: one uses a device that shows a waveform on a screen, and the other uses a color-changing test. It may help doctors choose the best method for patients in the emergency room or ICU.
Chicago, IllinoisAges 18 years+ - NCT06939361Enrolling by invitation
Tube size study during emergency breathing tube placement
This trial compares different sizes of breathing tubes used in emergencies to see which works best. It helps doctors choose the right tube for patients who need help breathing.
Birmingham, AlabamaAges 18 years+ - NCT01571986Recruiting
Improving non-invasive breathing support
This study is looking at ways to improve non-invasive ventilation, which is breathing support given without a breathing tube. You may be invited if you’re already receiving this kind of support and you agree to take part.
MilanAges 18–99 - NCT06848218Recruiting
Music therapy during non-invasive breathing support for children
This study tests if music therapy can help children who are receiving breathing support (non-invasive ventilation) in the pediatric intensive care unit. It aims to reduce stress and discomfort during treatment.
MontpellierAges Up to 17 years - NCT06441760Recruiting
Telemedicine support for paramedics in children's emergencies
This study tests whether paramedics and emergency doctors can use a special video or phone link to improve care for children in emergencies. It compares the usual way doctors give advice to paramedics with a new telemedicine method.
Los Angeles, CaliforniaAges 21 years+
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Common questions
- Are there clinical trials for acute respiratory failure?
- Yes. Clin2 currently lists 172 recruiting acute respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.