Clinical trials
Acute Respiratory Failure clinical trials
Below are recruiting acute respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 178 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06183827Recruiting
Drowning breathing failure oxygen trial
This trial compares two ways to give oxygen to people who have trouble breathing after drowning. It aims to find the best approach in the emergency setting.
BayonneAges 1 year+ - NCT06189924Recruiting
Breath analysis in ventilated ICU patients
This study collects and analyzes the moisture you breathe out while on a ventilator in the ICU. It aims to learn more about your condition by examining your breath.
OlomoucAges 18 years+ - NCT06438302Recruiting
Nasal ventilation for patients on a breathing machine
This trial tests whether using a nasal ventilation mask affects how well the brain and lungs work in people who are already on a breathing machine. It is for patients with very low oxygen levels who have been intubated for less than 4 days.
ParisAges 18 years+ - NCT06441760Recruiting
Telemedicine support for paramedics in children's emergencies
This study tests whether paramedics and emergency doctors can use a special video or phone link to improve care for children in emergencies. It compares the usual way doctors give advice to paramedics with a new telemedicine method.
Los Angeles, CaliforniaAges 21 years+ - NCT06531005Recruiting
Checking breathing to predict when a breathing tube can be removed in the ICU
This study looks at how well current breathing measures predict a patient's readiness to have their breathing tube removed in the intensive care unit (ICU). It aims to make the decision to remove the tube safer and more accurate.
Altindağ, AnkaraAges 18 years+ - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT06848218Recruiting
Music therapy during non-invasive breathing support for children
This study tests if music therapy can help children who are receiving breathing support (non-invasive ventilation) in the pediatric intensive care unit. It aims to reduce stress and discomfort during treatment.
MontpellierAges Up to 17 years - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06996834Recruiting
Comparing breathing support methods for pneumonia-related breathing failure
This trial tests two noninvasive breathing support methods (NIV and HVNI) for people with pneumonia who are having trouble breathing. The goal is to see which method works better to help you avoid needing a breathing tube.
Asyut, AssuitAges 18 years+ - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT06179485Enrolling by invitation
Ketamine vs. Etomidate for emergency breathing tube: long-term study
This study compares how two common medicines (ketamine and etomidate) used during emergency breathing tube placement affect long-term recovery. It is only for patients already enrolled in another related trial.
Birmingham, AlabamaAges 18 years+ - NCT07499661Recruiting
Study of blood clots in the lungs with heart failure
This study looks at whether a blood clot in the lungs (pulmonary embolism) is a hidden cause in patients who are hospitalized for acute heart failure. It involves additional imaging tests to find a clot if present, which could change your treatment.
AgenAges 18 years+ - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT06624254Enrolling by invitation
Breathing machine settings for lung recovery in ICU
This study looks at how a specific type of breathing machine setting (adaptive pressure control) affects your lungs and recovery. It aims to find the best way to support breathing for people in the ICU with respiratory failure.
La Jolla, CaliforniaAges 18 years+ - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Newport Beach, CaliforniaAges 18 years+ - NCT06769360Recruiting
Pressure support breathing trial for ICU patients
This trial tests a new way to set the breathing machine's pressure support based on your muscle effort. It may help you breathe more comfortably and improve recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT04707729Recruiting
Checking when to intubate patients on nasal high-flow oxygen
This study looks at a scoring system (ROX Index) to help decide the best timing to place a breathing tube (intubate) for adults who are struggling to get enough oxygen while using nasal high-flow (NHF). The goal is to see if using this timing approach can improve care for acute lung failure in the ICU.
Chicago, IllinoisAges 18–120 - NCT05011877Recruiting
Study for sleep testing after sudden breathing trouble
This trial studies people who unexpectedly end up in the hospital or emergency room because of a sudden worsening in breathing that leads to too much carbon dioxide. It may help doctors understand whether sleep-related breathing issues contribute and how to better prevent repeat episodes.
Toronto, OntarioAges 18 years+ - NCT05513508Recruiting
Tested a protective breathing mask in COPD and respiratory failure
This study tests how well a specific breathing mask setup works in people who need noninvasive ventilation (breathing support without a breathing tube), especially during COPD flare-ups or certain kinds of breathing failure. It may help reduce complications related to the mask while supporting breathing for at least a day.
NovaraAges 18 years+ - NCT06104956Recruiting
Weaning from high-flow oxygen therapy in the ICU
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
BloisAges 18–90 - NCT06438198Recruiting
Early switch to assisted breathing for lung failure
This trial tests switching patients from full ventilator support to a more gentle, assisted breathing mode earlier than usual. It may help people with severe lung failure recover faster and avoid complications from prolonged deep sedation.
RotterdamAges 18 years+ - NCT06526598Recruiting
Breathing support tailored to your effort in the ICU
This trial tests a new way of adjusting breathing machine support based on how hard you are breathing. It may help people with low oxygen levels who need a ventilator.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for acute respiratory failure?
- Yes. Clin2 currently lists 178 recruiting acute respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.