Clinical trials
Acute Respiratory Failure clinical trials
Below are recruiting acute respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06438302Recruiting
Nasal ventilation for patients on a breathing machine
This trial tests whether using a nasal ventilation mask affects how well the brain and lungs work in people who are already on a breathing machine. It is for patients with very low oxygen levels who have been intubated for less than 4 days.
ParisAges 18 years+ - NCT06401239Recruiting
Study on recovery from severe breathing problems
This study looks at how recovery goes for people who had severe breathing problems in the hospital. It involves talking with you and a partner who helps care for you, to learn how to improve support for both of you.
Baltimore, MarylandAges 18 years+ - NCT06322719Recruiting
Comparing two blades for intubation in the ICU
This trial tests which blade (hyperangulated or Macintosh) works better when doctors use a video laryngoscope to place a breathing tube in intensive care patients. It may help improve how intubation is done in the ICU.
Santiago de Compostela, A CoruñaAges 18–90 - NCT06307392Recruiting
Bougie versus tube for first-attempt breathing tube success
This trial compares two methods of placing a breathing tube during a medical emergency outside the hospital: using a flexible device called a bougie versus just the tube alone. It aims to see which method is more successful on the first try.
Nantes, Loire AtlantiqueAges 18 years+ - NCT06183827Recruiting
Drowning breathing failure oxygen trial
This trial compares two ways to give oxygen to people who have trouble breathing after drowning. It aims to find the best approach in the emergency setting.
BayonneAges 1 year+ - NCT06189924Recruiting
Breath analysis in ventilated ICU patients
This study collects and analyzes the moisture you breathe out while on a ventilator in the ICU. It aims to learn more about your condition by examining your breath.
OlomoucAges 18 years+ - NCT06179485Enrolling by invitation
Ketamine vs. Etomidate for emergency breathing tube: long-term study
This study compares how two common medicines (ketamine and etomidate) used during emergency breathing tube placement affect long-term recovery. It is only for patients already enrolled in another related trial.
Birmingham, AlabamaAges 18 years+ - NCT06042621Enrolling by invitation
Improving communication in the ICU for patients, families, and staff
This study looks at how doctors, nurses, and other healthcare team members talk with patients and their families in the intensive care unit (ICU). It aims to improve understanding and support for everyone involved.
Chicago, IllinoisAges 18 years+ - NCT05624450RecruitingPhase 3
Test drug tozorakimab for hospitalized viral lung infection needing oxygen
This Phase 3 study tests tozorakimab to see if it helps people hospitalized with a viral lung infection that is causing low oxygen levels. You might qualify if you still need supplemental oxygen when the study starts.
Birmingham, AlabamaAges 18 years+ - NCT04273607RecruitingPhase 2/Phase 3
Test an ECMO approach without blood thinners for lung failure
This trial studies whether people on a breathing machine called VV-ECMO can be managed without routine blood thinners, to reduce bleeding risk. It is meant for adults with severe lung failure (ARDS) and checks that it is safe for you to avoid anticoagulation.
Toronto, OntarioAges 18 years+ - NCT07499661Recruiting
Study of blood clots in the lungs with heart failure
This study looks at whether a blood clot in the lungs (pulmonary embolism) is a hidden cause in patients who are hospitalized for acute heart failure. It involves additional imaging tests to find a clot if present, which could change your treatment.
AgenAges 18 years+ - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT06624254Enrolling by invitation
Breathing machine settings for lung recovery in ICU
This study looks at how a specific type of breathing machine setting (adaptive pressure control) affects your lungs and recovery. It aims to find the best way to support breathing for people in the ICU with respiratory failure.
La Jolla, CaliforniaAges 18 years+ - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT05513508Recruiting
Tested a protective breathing mask in COPD and respiratory failure
This study tests how well a specific breathing mask setup works in people who need noninvasive ventilation (breathing support without a breathing tube), especially during COPD flare-ups or certain kinds of breathing failure. It may help reduce complications related to the mask while supporting breathing for at least a day.
NovaraAges 18 years+ - NCT07615010RecruitingPhase 2
agenT-797 Plus Standard Care for Severe Pneumonia With Respiratory Failure
This trial tests whether adding an experimental drug called agenT-797 to standard pneumonia treatment helps patients in the ICU who have severe pneumonia and serious difficulty breathing (acute hypoxemic respiratory failure). The drug is designed to help the immune system fight severe infection.
San Francisco, CaliforniaAges 18 years+ - NCT06699433Recruiting
AI virtual pediatric patient training for primary care doctors
This trial uses artificial intelligence to create virtual standardized pediatric patients. It helps train doctors who work in primary care settings, like community health centers and clinics.
Guiyang, GuizhouAges Any age - NCT06769360Recruiting
Pressure support breathing trial for ICU patients
This trial tests a new way to set the breathing machine's pressure support based on your muscle effort. It may help you breathe more comfortably and improve recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05011877Recruiting
Study for sleep testing after sudden breathing trouble
This trial studies people who unexpectedly end up in the hospital or emergency room because of a sudden worsening in breathing that leads to too much carbon dioxide. It may help doctors understand whether sleep-related breathing issues contribute and how to better prevent repeat episodes.
Toronto, OntarioAges 18 years+ - NCT07047092RecruitingPhase 3
CPAP vs. NIV for sleep apnea in COPD after breathing failure
This trial compares two breathing devices (CPAP and NIV) for people with both COPD and sleep apnea who recently needed breathing help in the hospital. The goal is to see which device works better at preventing future breathing emergencies.
ParisAges 18–84 - NCT06921655Recruiting
Using pressure and muscle measurement to avoid too much breathing help in the ICU
This study tests a new way to adjust the breathing machine settings for patients who are awake and breathing on their own but still need support. The goal is to avoid giving too much help, which can make the breathing muscles weak.
Trento, TrentoAges 18 years+ - NCT06104956Recruiting
Weaning from high-flow oxygen therapy in the ICU
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
BloisAges 18–90 - NCT06526598Recruiting
Breathing support tailored to your effort in the ICU
This trial tests a new way of adjusting breathing machine support based on how hard you are breathing. It may help people with low oxygen levels who need a ventilator.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+
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Common questions
- Are there clinical trials for acute respiratory failure?
- Yes. Clin2 currently lists 172 recruiting acute respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.