Clinical trials
Adaptive Radiotherapy clinical trials
Below are recruiting adaptive radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 76 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07269626RecruitingPhase 2
PULSAR therapy for pancreatic cancer
This trial tests whether adding a special type of radiation therapy (PULSAR) to standard chemotherapy can help control pancreatic cancer that has not spread far. It is for people who have already completed a few rounds of chemo without their cancer growing.
Seoul, Select Province/StateAges 19 years+ - NCT07459101Recruiting
MR-guided radiation therapy for high-grade brain tumors
This study tests a new way to deliver radiation therapy for a type of aggressive brain tumor called glioblastoma or grade 4 astrocytoma. Patients get MRI scans during each treatment so the radiation beam can be adjusted precisely, aiming to improve outcomes.
Toronto, OntarioAges 18 years+ - NCT06538337Recruiting
Shorter radiation therapy for endometrial and cervical cancer
This trial tests a shorter, more targeted type of radiation therapy for people with endometrial or cervical cancer who have had surgery. It aims to reduce side effects by using daily scans to adjust the treatment plan.
Los Angeles, CaliforniaAges 18 years+ - NCT07245745Recruiting
Comparing two types of radiotherapy for prostate cancer
This trial compares adaptive radiotherapy (which adjusts to changes in your body) with conventional radiotherapy for prostate cancer. It aims to see which approach leads to better patient-reported outcomes.
BrusselsAges 18 years+ - NCT06730295RecruitingPhase 2
Lung cancer radiation trial shrinking target margins
This trial tests a newer, more precise way of giving radiation for lung cancer tumors that are near the center of the chest. The goal is to see if using a smaller treatment area can reduce side effects while still killing the cancer.
Guangzhou, GuangdongAges 18 years+ - NCT05896865Recruiting
Personalized breast cancer radiation based on tumor biology
This trial studies whether adjusting radiation dose using how the tumor behaves can improve outcomes for people with locally advanced breast cancer that has spread to certain nearby lymph nodes. It may help deliver the right radiation intensity while avoiding unnecessary exposure.
SeoulAges 19 years+ - NCT06313541RecruitingPhase 2
Adaptive radiation with immunotherapy for advanced lung cancer
This trial is testing a combination of immunotherapy and targeted radiation for people with advanced lung cancer that has no targetable gene changes. The goal is to see if adjusting radiation based on how well the tumor responds can improve outcomes.
ShanghaiAges 18 years+ - NCT06545747RecruitingPhase 3
MRI-guided radiation for advanced lung cancer
This trial tests a new way of giving radiation therapy for advanced lung cancer that cannot be surgically removed. It uses MRI scans to guide and adjust the radiation dose, which may help target the tumor more precisely and reduce side effects.
GuangzhouAges 18–75 - NCT07077239Recruiting
Adaptive radiation after prostate surgery to lower side effects
This trial tests a precise, short-course radiation treatment (stereotactic body radiotherapy) after prostate removal surgery that adapts to your body each day to reduce side effects. It is for people whose prostate cancer has high-risk features or a rising PSA after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07344844Recruiting
Custom Stereo Radiography for Early Prostate Cancer
This study tests a precise type of radiation (stereotactic radiotherapy) for men with early-stage prostate cancer. It aims to see if using custom radiation beams improves outcomes while reducing side effects.
Saint-DenisAges 60 years+ - NCT07381231RecruitingPhase 2
Immunotherapy with targeted radiation for solid tumors
This trial tests combining immunotherapy (checkpoint inhibitors) with precisely-targeted radiation pulses to see if this approach works better against solid tumors. It may help people who are already on or starting immunotherapy.
SeoulAges 19 years+ - NCT05027711RecruitingPhase 2
MRI-guided precise radiation for liver metastases
This Phase 2 trial tests an MRI-guided, highly targeted radiation treatment (SBRT) for tumors that have spread to the liver. It may help shrink 1–3 liver metastases while using imaging to better guide treatment.
HeidelbergAges 18 years+ - NCT06834152Recruiting
Online adaptive radiation for localized prostate cancer
This trial tests a new way to deliver high-precision radiation to the prostate using daily MRI or CT scans to adjust the treatment based on your exact anatomy. It aims to make radiation more accurate and reduce side effects.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07223307RecruitingPhase 2
MRI-guided radiation for liver cancers
This trial tests a precise MRI-guided radiation treatment for liver cancers, including liver cancer, bile duct cancer, or cancer that has spread to the liver. The goal is to target tumors more accurately while protecting healthy tissue.
Palo Alto, CaliforniaAges 18 years+ - NCT07359443RecruitingPhase 1
Chemo plus MRI-guided radiation before esophageal cancer surgery
This trial tests combining chemotherapy (FLOT) with a special type of MRI-guided radiation before surgery for esophageal adenocarcinoma. It aims to improve treatment results for patients with a specific type and stage of the disease.
Utrecht, UtrechtAges 18 years+ - NCT07188532Recruiting
Personalized high-dose radiation for Ewing sarcoma
This trial tests a personalized radiation therapy that adjusts the dose based on your tumor. It aims to improve treatment for Ewing sarcoma while limiting side effects.
Phoenix, ArizonaAges 2 years+ - NCT06323460RecruitingPhase 2
Less Radiation for HPV Throat Cancer Guided by a Blood Test
This study tests a way to use less radiation for HPV-related throat cancer. Doctors will adjust your treatment based on a simple blood test that tracks cancer DNA, so you may get only the treatment you need.
Columbus, OhioAges 18 years+ - NCT06844422RecruitingPhase 1/Phase 2
Guided radiation plus chemo and immune drug for pancreatic cancer
This study tests whether a new combination of super-precise radiation (guided SBRT), standard chemotherapy, and a newer immune medicine called Ivonescimab can slow or shrink pancreatic tumors that cannot be removed by surgery. The goal is to find a more effective treatment option.
Jinan, ShandongAges 18–75 - NCT06325046Recruiting
Adaptive radiation therapy for localized prostate cancer
This trial tests a type of radiation that adapts to your body's changes during treatment. It is for men with low- to intermediate-risk prostate cancer that hasn't spread.
Albert Lea, MinnesotaAges 18 years+ - NCT06912763RecruitingPhase 2
Reversing radiation side effects in head and neck cancer
This trial tests a combined treatment (a statin and a drug that helps blood flow) to reverse long-term swelling and tissue hardening caused by head and neck radiation. It may help people who have had these side effects for more than 6 months.
Houston, TexasAges Any age - NCT06825091RecruitingPhase 3
Comparing new SBRT to standard radiation for prostate cancer
This trial compares a newer, more precise type of radiation (adaptive SBRT) with standard image-guided radiation for prostate cancer. It aims to see if the newer approach is better at targeting the tumor while reducing side effects.
Toronto, OntarioAges 18 years+ - NCT07154069RecruitingPhase 3
Immunotherapy for advanced nasopharyngeal cancer after chemo
This trial tests if adding an immunotherapy drug (PD-1 inhibitor) after standard induction chemotherapy helps keep advanced nasopharyngeal cancer from coming back. It is for people who have completed 3 cycles of GP chemotherapy combined with a PD-1 inhibitor and have not had their cancer progress.
Guangzhou, GuangdongAges 18–65 - NCT05838391Recruiting
Targeted radiation approach for anal cancer
This trial tests an adaptive, image-guided radiation plan for anal canal squamous-type cancers. It may help deliver effective treatment while adjusting the radiation based on how your body and tumor respond.
New York, New YorkAges 18 years+ - NCT05030207Recruiting
Test a new CT scan method for lung cancer radiation planning
This study tests whether a real-time, breathing-adapted CT scan (called 4DCT) can be done safely and work well for planning radiation treatment for lung cancer. It may help make radiation planning more accurate while checking if the scan process is practical for patients.
Blacktown, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for adaptive radiotherapy?
- Yes. Clin2 currently lists 76 recruiting adaptive radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adaptive radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adaptive radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.