Clinical trials
Adult clinical trials
Below are recruiting adult clinical trials, each written for real people, not researchers. We’re tracking 3,742 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05611775Recruiting
Spinal surgery patients tracked for daily activity after surgery
This trial follows adults who are getting a multi-level spinal deformity correction surgery with special pelvic attachment. It looks at how well you return to real-life function and activity after surgery using follow-up visits at Mayo Clinic.
Rochester, MinnesotaAges 18 years+ - NCT05612347Recruiting
Compare stool test vs colonoscopy for older adults with polyps
This study compares two ways to check for colon polyps in older adults: using a stool test versus having a colonoscopy. It may help find a simpler option if you only had a small number of lower-risk polyps before.
Birmingham, AlabamaAges 65–82 - NCT05606432Recruiting
Movement-to-music exercise program for people with mobility limits
This study tests whether a movement-to-music exercise program at home can improve cardiometabolic health (health related to heart and blood sugar) for adults who use a wheelchair and are not already exercising regularly. You may benefit if you can exercise using your arms and can do moderate activity safely.
Birmingham, AlabamaAges 18–89 - NCT05596539Recruiting
Study of adults with low alkaline phosphatase
This is a long-term observational study (not a drug trial) that follows adults with signs of hypophosphatasia, a condition linked to very low alkaline phosphatase levels and sometimes a gene change. It aims to better understand the condition over time and how symptoms look and progress.
Bordeaux, FranceAges 18 years+ - NCT05555069Recruiting
Menthol-flavored vaping study for adult menthol cigarette smokers
This study looks at how menthol flavoring may affect whether adult menthol cigarette smokers switch to e-cigarettes. You may be asked to switch and use e-cigarettes over a set period, while researchers track your smoking behavior.
Kansas City, MissouriAges 21 years+ - NCT05559853Recruiting
MRI scan study to track brain tumor changes after treatment
This study tests a new MRI (brain scan) method to see how brain tumors change over time after treatment. There are also parts for healthy adults to help with developing and comparing the scan technique.
New York, New YorkAges 18 years+ - NCT05574127Recruiting
Brief behavioral therapy for depression in older cancer survivors
This study tests a brief behavioral activation program to help older cancer survivors with depression. It involves 10 sessions (or a shorter version) to improve mood and quality of life.
New York, New YorkAges 65 years+ - NCT05584449Recruiting
After-cancer group program for young adult survivorship goals
This trial offers a structured group curriculum to help young adults after cancer treatment manage survivorship concerns and improve outcomes. You may be eligible if you finished curative cancer treatment recently and can fully join all six group meetings.
Scottsdale, ArizonaAges 18–39 - NCT05577754RecruitingPhase 2
Trial tests alpelisib for MCAP with PIK3CA mutations
This Phase 2 study tests alpelisib in children and adults with MCAP, a condition caused by a specific PIK3CA gene mutation. The goal is to see if the treatment is effective and safe, while carefully monitoring blood sugar and organ function.
AmiensAges 2–40 - NCT05577143Recruiting
Blood test screening for colorectal cancer
This study checks whether a blood test can help identify colorectal cancer or precancerous growths. You would have a planned colonoscopy, and researchers compare the blood test results to what the colonoscopy finds.
LilleAges 18–75 - NCT05584670RecruitingPhase 1/Phase 2
Testing a new cancer drug for advanced solid tumors
This is an early (Phase 1/2) study of SAR445877, a new drug, in adults with advanced or metastatic solid cancers. It aims to find the safest dose and learn whether it can shrink tumors or help control disease when standard treatments aren’t available or no longer work.
Newark, DelawareAges 18 years+ - NCT05587049Recruiting
Testing an oral medicine plus azacitidine to improve AML disease
This study looks at how a standard AML treatment plan affects a person’s disease status over time. It focuses on newly diagnosed adults who cannot safely get intensive chemotherapy, using oral venetoclax plus azacitidine.
Medellín, AntioquiaAges 18 years+ - NCT05588648RecruitingPhase 1/Phase 2
Vactosertib for recurrent or progressive bone cancer
This trial tests a new drug called vactosertib for people with a type of bone cancer called osteosarcoma that has come back or hasn't responded to other treatments. The goal is to see if the drug can help shrink or slow the cancer and to check its safety.
Cleveland, OhioAges 12 years+ - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT05533775RecruitingPhase 1/Phase 2
Study of an antibody medicine with or without chemotherapy for relapsed lymphoma
This trial tests glofitamab alone or with chemotherapy and immunotherapy in children and young adults whose “mature B-cell” non-Hodgkin lymphoma has come back or hasn’t responded to treatment. It looks at whether the study medicines can shrink lymphoma again and are safe enough to use in this age group.
Birmingham, AlabamaAges 6 months–30 years - NCT05545007Recruiting
Pre-op vs post-op focused radiation for large brain metastases
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Brescia, BresciaAges 18 years+ - NCT05535855RecruitingPhase 1
UCD19 CAR T for adult ALL with MRD in remission
This early-phase study tests a personalized immune-cell treatment (CAR T) for adults with B-cell acute lymphoblastic leukemia (ALL) who still have tiny amounts of cancer detectable by a special test called MRD. It aims to improve outcomes for people who are in first remission but not completely “cancer-free” by MRD testing.
Aurora, ColoradoAges 18 years+ - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05505500Recruiting
Parent and patient interviews for childhood kidney swelling
This study uses interviews to understand how swelling from nephrotic syndrome affects daily life for children and their caregivers. It may help researchers design better care by capturing the patient and parent perspective.
Ann Arbor, MichiganAges 2 years+ - NCT05545501Recruiting
Testing a ketone drink and salt in healthy young adults
This study tests how a ketone ester plus salt affects the body in young adults. It likely looks at safety and what changes you can measure after taking it.
Bloomington, IndianaAges 19–39 - NCT05524298Recruiting
Quality of life study in older adults with low-grade lymphoma
This study looks at quality of life in people age 70 and older with slow-growing (low-grade) B-cell non-Hodgkin lymphoma who haven’t been treated yet. It requires a geriatric (aging-focused) check before starting care, to see what helps older patients feel better during treatment.
Alessandria, AlessandriaAges 70 years+ - NCT05522075Recruiting
Reducing Blood Pressure in Adults Who Binge Drink
This study looks at ways to lower blood pressure in adults ages 50–64 who drink little, moderate, or binge drink. It may help by testing an approach that supports healthier blood pressure in midlife.
Arlington, TexasAges 50–64 - NCT05538871Recruiting
Testing body movement and physical capacity in scoliosis adults
This study checks how well people can move and perform physical tasks if they have scoliosis (an uneven spine), or if they’re a healthy comparison group. It may help researchers better understand how body structure and function are affected by different types of scoliosis.
Edmonton, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for adult?
- Yes. Clin2 currently lists 3,742 recruiting adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.