Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,090 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06940050Recruiting
Gum graft study for lower jaw recessions
This study compares two gum grafting methods (one using a special collagen material plus soft tissue, the other using soft tissue alone) to treat multiple gum recessions on the lower jaw. It may help find a better way to cover exposed roots and improve gum health.
Ghent, Oost-VlaanderenAges 18 years+ - NCT06937996Recruiting
NanoKnife treatment for advanced pancreatic cancer
This trial studies a procedure called NanoKnife IRE for pancreatic cancer that cannot be removed surgically after standard chemotherapy or radiation. It uses electric pulses to destroy tumor cells and may be an option for patients who have completed other treatments.
Englewood, New JerseyAges 18 years+ - NCT06938282RecruitingPhase 2
Study of HRS-4642 with immunotherapy and chemo for pancreatic cancer
This trial tests a new drug combination for pancreatic cancer that has not been treated before. It may help shrink tumors or make surgery possible for people with advanced or borderline resectable disease.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02843945RecruitingPhase 1/Phase 2
Testing radiation for borderline pancreatic surgery using a tiny implant
This early trial studies whether adding targeted radiation during or around pancreatic surgery is safe and may improve outcomes for people with borderline resectable pancreatic cancer. It is mainly looking at feasibility and safety while treating close to the tumor but not spreading (no metastasis).
Tampa, FloridaAges 18 years+ - NCT06923618Recruiting
Lung Cancer and Aging in Older Adults
This trial looks at aging-related changes in older adults (70+) with early-stage lung cancer who are planning to have surgery. The goal is to better understand how these changes might affect recovery and outcomes, which could help improve care for future patients.
Créteil, Île-de-France RegionAges 70 years+ - NCT06929663RecruitingPhase 1
Study of AK146D1 for advanced solid tumors
This study tests an experimental drug (AK146D1) for people with advanced solid tumors that are no longer responding to standard treatments. The goal is to see if it is safe and effective.
Sydney, New South WalesAges 18–75 - NCT06927349RecruitingPhase 1
A trial of BA1301 for advanced solid tumors
This trial tests a new drug, BA1301, in people with advanced solid tumors that have not responded to standard treatments. The study aims to find a safe dose and see if BA1301 can help shrink or control the cancer.
Harbin, HeilongjiangAges 18–75 - NCT06925581RecruitingPhase 1/Phase 2
Trial of HRS-6768 for advanced solid tumors
This trial tests a new drug called HRS-6768 for people with advanced solid tumors that have stopped responding to standard treatments or have no good options. It aims to see if the drug is safe and effective.
Beijing, Beijing MunicipalityAges 18–80 - NCT06926283RecruitingPhase 1
Study of DXC008 for advanced prostate and other solid tumors
This trial tests a new drug called DXC008 for people with advanced solid tumors, including prostate cancer, that have not responded to standard treatments. The goal is to see if it can help shrink tumors or slow their growth.
Changsha, HunanAges 18–75 - NCT06927570RecruitingPhase 1
Study of HS-20122 for advanced solid tumors
This trial tests a new drug called HS-20122 in people with advanced solid tumors that have not responded to standard treatments. The goal is to see if it is safe and effective.
Guangzhou, GuangdongAges 18 years+ - NCT06449339RecruitingPhase 4
Beta-blocker study for early-stage liver scarring
This study tests a medicine called carvedilol (a non-selective beta-blocker) to see if it can prevent complications in people with advanced chronic liver disease who are at high risk but haven't had serious problems like bleeding yet.
Hong KongAges 18 years+ - NCT06915142RecruitingPhase 2
Study of HRS-7058 combined with cancer drugs for advanced solid tumors
This trial tests a new drug, HRS-7058, combined with other anti-cancer drugs for people with advanced solid tumors that cannot be surgically removed. The goal is to see if the combination can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges 18–75 - NCT06911827RecruitingPhase 1/Phase 2
Combination drug study for advanced solid tumor cancer
This trial tests a combination of two new treatments (QLP2117 and QL2107) for people with advanced solid tumors that have not responded to standard therapy. The goal is to see if the combination can shrink tumors or slow cancer growth.
Guangzhou, GuangdongAges 18 years+ - NCT06907043RecruitingPhase 1/Phase 2
Study of PARP1 inhibitor EIK1004 for advanced solid tumors
This trial is testing a new drug (EIK1004) designed to block a protein called PARP1, which helps repair DNA. It is for people with advanced solid tumors, especially those with BRCA or other DNA repair gene mutations. The goal is to see if it can shrink tumors or slow their growth.
Denver, ColoradoAges 18–89 - NCT06905405Recruiting
Imaging for early heart failure with stiff heart muscle (HFpEF)
This study uses advanced imaging to find early signs of a type of heart failure where the heart pumps well but doesn't relax properly (HFpEF). It may help if you have shortness of breath and a slightly enlarged heart chamber but don't yet have a clear heart failure diagnosis.
Sheffield, South YorkshireAges 18 years+ - NCT06904456Recruiting
Advanced HIV study in Zambia for those starting HIV treatment
This study looks at people with advanced HIV disease during their first months on antiretroviral therapy (ART). It aims to understand and improve care for those who start treatment when their immune system is weak.
LusakaAges 18 years+ - NCT06910722Recruiting
Liver transplant for bile duct cancer after treatment
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. Before the transplant, you would receive radiation therapy (SIRT) and chemotherapy to shrink the tumor.
Clichy-sous-BoisAges 18–65 - NCT06902272RecruitingPhase 2
Blood test to predict chemo-immunotherapy response in lung cancer
This trial tests whether a blood test (ctDNA) can help predict how well a combination of chemotherapy and immunotherapy (and sometimes radiation) works before surgery for non-small cell lung cancer. It aims to see if the blood test can detect small amounts of remaining cancer to guide further treatment.
Miami, FloridaAges 18 years+ - NCT06902389RecruitingPhase 1/Phase 2
Multi-target immune cell therapy for advanced liver cancer
This trial tests a new type of immune cell therapy (multi-target Hi-TCR-T cells) for people with advanced liver cancer that hasn't responded to earlier treatments. The therapy targets several markers on your cancer cells to try to attack the tumor more effectively.
Shanghai, Yangpu DistrictAges 18–75 - NCT06899126RecruitingPhase 3
Study of a drug combo for first-line HER2-positive lung cancer
This trial tests a new combination of drugs (trastuzumab deruxtecan, pembrolizumab, and chemotherapy) as a first treatment for people with advanced non-small cell lung cancer that has high levels of the HER2 protein. The goal is to see if this combination works better than current options.
Anchorage, AlaskaAges 18 years+ - NCT06817174Recruiting
CT scan analysis for ovarian cancer treatment planning
This study uses advanced computer analysis of CT scans to help doctors plan the best treatment for advanced ovarian cancer. It is designed for patients who are about to start active treatment, such as surgery or chemotherapy.
LondonAges 18 years+ - NCT06825546RecruitingPhase 2
Icaritin plus chemo for advanced pancreatic cancer
This trial tests a new combination of a plant-based drug (icaritin) and two chemotherapy drugs (AG) for people with advanced pancreatic cancer who have not had treatment before. The goal is to see if the combination works better than chemotherapy alone.
Guangzhou, GuangdongAges 18–80 - NCT06890273Recruiting
Study of durvalumab and olaparib for endometrial cancer
This study looks at how well two drugs, durvalumab and olaparib, work together after initial chemotherapy for advanced or recurrent endometrial cancer. It may help patients who have not had many treatment options before.
AmbergAges 18–130 - NCT06882135RecruitingPhase 1
Testing an experimental drug for advanced solid tumors
This trial studies a new drug called HW071021 for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug can help shrink or control the cancer.
Guangzhou, GuangdongAges 18 years+
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,090 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.