Clinical trials
Advanced clinical trials
Below are recruiting advanced clinical trials, each written for real people, not researchers. We’re tracking 3,959 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07446244Enrolling by invitation
Catheter ablation for advanced atrial fibrillation
This trial tests a special type of catheter ablation (using electric pulses called electroporation) to treat people with long-lasting atrial fibrillation and a very enlarged left atrium. It may offer a new treatment option when standard approaches are limited.
Ljubljana, OsrednjaslovenskaAges Up to 80 years - NCT07426224Enrolling by invitation
Blood sugar screening for advanced gum disease patients
This trial checks if treating advanced gum disease at a specialist clinic can help find hidden high blood sugar and support you in managing your overall health.
StockholmAges 18 years+ - NCT07395505Enrolling by invitation
Surgery for advanced rectal or anal cancer
This trial studies the results of a major surgery called pelvic exenteration for patients with advanced rectal or anal cancer that has spread to nearby tissues or bones but not to distant organs. The goal is to see how well the surgery works and how patients recover afterward.
TaoyuanAges 20 years+ - NCT07371247Enrolling by invitationEarly Phase 1
Adjuvant treatment guided by ctDNA after chemoradiation for esophageal cancer
This trial tests whether adjusting treatment based on a blood test (ctDNA) after standard chemoradiation can improve outcomes for patients with advanced esophageal squamous cell carcinoma. It aims to find a more personalized approach to prevent cancer recurrence.
Nanjing, JiangsuAges 18–80 - NCT07356466Enrolling by invitationEarly Phase 1
Combination therapy vs. standard chemo for advanced stomach cancer
This trial tests whether adding two newer drugs (pucotenlimab and lenvatinib) to standard chemotherapy (SOX) works better than chemotherapy alone for people with advanced stomach or gastroesophageal junction cancer that is HER2-negative. The goal is to see if the combination slows cancer growth.
Fuzhou, FujianAges 18–75 - NCT07312136Enrolling by invitation
Liver health follow-up in type 2 diabetes
This study follows up on people who already joined the EPSONIP trial to check how their liver health (MASLD) has changed over time. It uses MRI to look at the liver and does not test any new medicine.
Linköping, Östergötland CountyAges 18 years+ - NCT07311070Enrolling by invitationPhase 3
Methylene blue gel for skin cancer not treated by surgery or radiation
This trial tests a methylene blue gel for people with certain types of basal cell carcinoma (a common skin cancer) who cannot have surgery or radiation. The goal is to see if the gel can treat the cancer safely and effectively.
Mashhad, Razavi Khorasan ProvinceAges 18 years+ - NCT07310069Enrolling by invitationPhase 2
Testing a new drug combination for advanced gallbladder cancer
This trial tests a combination of two chemotherapy drugs (gemcitabine and nab-paclitaxel) with two immunotherapy drugs (iparomlimab and tuvorilimab) for people with advanced gallbladder cancer that cannot be removed by surgery. The goal is to see if this combination can help shrink the cancer or slow its growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07285434Enrolling by invitationEarly Phase 1
Personalized vaccine for first-line advanced lung cancer
This study tests a personalized vaccine (Microlyvaq™) made just for your tumor, given together with standard chemo and immunotherapy (pembrolizumab). It is for people with advanced non-small cell lung cancer who have not yet started treatment for the advanced stage.
Thessaloniki, MacedoniaAges Any age - NCT07206888Enrolling by invitation
Study to try advanced ultrasound for breast imaging
This study explores a new way to process ultrasound images of the breast. It is for women who have a finding, cyst, mass, or calcifications seen on a mammogram or ultrasound, and it uses a special ultrasound technique that may provide clearer images without extra radiation.
Baltimore, MarylandAges 18 years+ - NCT07178028Enrolling by invitation
Balance check: in-person vs. video for older adults
This study compares in-person balance assessments with video-based (telehealth) assessments for older adults. It aims to see if balance can be checked reliably over a video call, making it easier for you to participate from home.
Istanbul, BüyükçekmeceAges 65 years+ - NCT07176234Enrolling by invitation
Linking exercise for better stress management in teens
This study tests whether a home-based exercise program can help African American teens (ages 11–16) manage daily stress. It compares the program to a healthy lifestyle education group.
Columbia, South CarolinaAges 11–16 - NCT07012850Enrolling by invitation
MRI for dental and facial injury evaluation
This study uses MRI instead of CT or X-ray to look at injuries to teeth, mouth, and face. It might help find a safer way to image your injury without radiation.
Zurich, Canton of ZurichAges Any age - NCT06970171Enrolling by invitation
Willingness to use a sleep apnea mouthpiece
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Greifswald, Mecklenburg-VorpommernAges 18–75 - NCT06963060Enrolling by invitationPhase 2
Gem+Nab-P+LEN+TIS for Advanced Unresectable BTC (GALENT-BT)
This trial tests a combination of four drugs (gemcitabine, nab-paclitaxel, lenvatinib, and tislelizumab) for people with advanced bile duct or gallbladder cancer that cannot be removed by surgery and has not been treated before.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06962449Enrolling by invitation
Study of Tislelizumab as First Treatment for Advanced Lung Cancer
This study looks at how well Tislelizumab works as the first treatment for advanced non-small cell lung cancer that has spread. It aims to understand which treatment strategies after Tislelizumab lead to the best survival outcomes for patients.
Shanghai, Shanghai MunicipalityAges Any age - NCT06901622Enrolling by invitationPhase 2
Testing a combination of drugs for advanced gallbladder and bile duct cancer
This trial tests whether adding a targeted therapy (anlotinib) to standard chemo plus an immunotherapy (camrelizumab) is more effective than chemo plus immunotherapy alone for advanced gallbladder or bile duct cancers that cannot be removed by surgery.
ZhengzhouAges 18–75 - NCT06890871Enrolling by invitationPhase 1/Phase 2
Radiation with immunotherapy and anti-angiogenic therapy for advanced HER2-negative breast cancer
This trial tests a combination of radiation therapy, immunotherapy, and a drug that blocks blood vessel growth for advanced HER2-negative breast cancer that has spread. It is for patients whose cancer has worsened after at least two prior treatments.
Wuhan, HubeiAges 18–75 - NCT06888700Enrolling by invitation
tDCS to improve social thinking in heroin recovery
This study uses a gentle brain stimulation technique called tDCS (transcranial direct current stimulation) to improve social thinking skills in people recovering from heroin addiction. It's for adults in early recovery who are in a rehabilitation center.
Xi'an, ShaanxiAges 30–60 - NCT06883136Enrolling by invitation
Sintilimab plus chemo for elderly advanced lung cancer
This trial tests a combination of the immunotherapy drug sintilimab plus standard chemotherapy (platinum-based doublet) as the first treatment for older adults (60–80) with advanced non-small cell lung cancer that does not have certain gene mutations. The goal is to see if this approach works better than chemotherapy alone.
Jinan, ShandongAges 60–80 - NCT06883084Enrolling by invitation
How lymph node changes affect rectal cancer outcomes
This trial looks at how much the lymph nodes respond to chemoradiation before surgery in people with locally advanced rectal cancer. It aims to understand if that response can predict long-term results and guide future treatment choices.
Ages 18–65 - NCT06849362Enrolling by invitation
Optimizing immunotherapy for advanced colorectal cancer
This study looks at how well different combinations of immunotherapy drugs work for advanced colorectal cancer that is MSS or MSI-L or pMMR. It reviews past patient records to see which treatments help control the disease and slow its growth.
Changsha, HunanAges Any age - NCT06838468Enrolling by invitation
Study on liver health in alcohol detox patients
This study is looking at liver health in people staying in a detox unit for alcohol use disorder. Researchers want to see how common liver problems are in this group. Participating involves extra tests like blood work, an ultrasound, and a special liver scan (FibroScan).
Sabadell, BarcelonaAges 18–75 - NCT06826157Enrolling by invitation
Brain Wave Patterns in Early Memory Loss and Dementia
This study uses an advanced EEG (electroencephalogram) to measure brain wave activity in people with early Alzheimer's, frontotemporal dementia, or Lewy body dementia. It aims to find patterns that could help doctors better understand the disease and predict how it might progress.
Milan, ItalyAges 50–85
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Common questions
- Are there clinical trials for advanced?
- Yes. Clin2 currently lists 3,959 recruiting advanced studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.