Clinical trials
Agitation clinical trials
Below are recruiting agitation clinical trials, each written for real people, not researchers. We’re tracking 57 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07144007Recruiting
Preventing agitation after rhinoplasty with propofol and dexmedetomidine
This study tests whether giving two medicines, propofol and dexmedetomidine, during rhinoplasty can help prevent confusion or restlessness when waking up from anesthesia. It may be a good option if you are having nose surgery and are generally healthy.
Van, TuşbaAges 18–65 - NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Tanta, El-GharbiaAges 3–7 - NCT07389135Recruiting
Heart rate and anxiety after nose surgery study
This study looks at whether your heart rate patterns and anxiety levels before surgery can predict how you will wake up after nose surgery (septorhinoplasty). If you are scheduled for this surgery, they will measure your heart rate and ask you questions about anxiety to see if these can help reduce confusion or agitation when you wake up.
Konya, KaratayAges 18–65 - NCT07510516Recruiting
Verbal reminders to reduce confusion after anesthesia
This study tests whether giving a simple verbal reminder (like telling you where you are) after anesthesia can help reduce confusion or agitation when waking up. It is for adults having laparoscopic abdominal surgery under a specific inhaled anesthetic.
Lahore, Punjab ProvinceAges 18–70 - NCT07523438Recruiting
Nasal Medication to Reduce Agitation After Eye Surgery in Young Children
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
AlexandriaAges 3–6 - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years - NCT07568093Recruiting
Music therapy to reduce agitation after abdominal surgery
This study tests whether listening to music after abdominal surgery can help reduce agitation and anxiety during recovery. Researchers will compare patients who receive music therapy with standard care to see if it improves comfort and outcomes.
Hanover, Lower SaxonyAges 18 years+ - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT05091242RecruitingPhase 2/Phase 3
Preventing agitation after anesthesia in babies up to 1 year old
This study tests a way to reduce post-surgery agitation (confusion or restlessness) in babies aged 3 to 12 months who need anesthesia for a procedure. The goal is to make recovery calmer and safer for your baby.
Perth, NedlandsAges 3 months–1 year - NCT07011732RecruitingPhase 3
Testing a drug for Alzheimer's-related agitation
This study tests an experimental drug (KarXT) to see if it safely reduces agitation in people with Alzheimer's disease. It may help if you or your loved one experiences restlessness, aggression, or irritability related to Alzheimer's.
Scottsdale, ArizonaAges 55–90 - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT05044832Recruiting
Personalized music to reduce agitation after certain surgeries
This study tests whether playing personalized music during and after specific surgeries can reduce “emergence agitation,” a period of distress or confusion as a patient wakes up from anesthesia. It may help children feel calmer by using music they connect with.
Stanford, CaliforniaAges 3–9 - NCT07677917Enrolling by invitationPhase 1
Medicine to reduce restlessness after sinus surgery
This trial tests two inhaled medicines, dexmedetomidine and magnesium sulfate, to see which is better at preventing agitation and restlessness as patients wake up from functional endoscopic sinus surgery. It may help you recover more calmly.
CairoAges 21–50 - NCT07011745RecruitingPhase 3
Study of KarXT for Alzheimer's Agitation
This study tests a new drug combination (KarXT + KarX-EC) to see if it can safely reduce agitation in people with Alzheimer's disease. It may help if you or your loved one has bothersome agitation that affects daily life.
Chandler, ArizonaAges 55–90 - NCT07730957Recruiting
Music program to reduce care refusal in nursing home residents
This trial tests whether a structured music program can help reduce care refusal (like agitation or aggression during bathing) in nursing home residents with memory or thinking problems. Residents who show these behaviors may be eligible.
AmiensAges 18 years+ - NCT03082755RecruitingPhase 4
Study sleep agitation and restless legs in Alzheimer’s patients
This trial studies treatment for troubling nighttime restlessness and agitation in people with Alzheimer’s disease. It may help improve sleep and nighttime comfort and reduce nighttime behavior problems.
Austin, TexasAges 55 years+ - NCT04436081RecruitingPhase 2
CBD oil without THC for agitation in Alzheimer’s dementia
This trial studies whether a THC-free CBD oil softgel can reduce agitation in people with Alzheimer’s-related dementia. It compares CBD to a control to see if it improves difficult behaviors and is safe over the study period.
Norfolk, VirginiaAges 50–90 - NCT04824144RecruitingPhase 1/Phase 2
Dexmedetomidine for agitation in palliative care delirium
This trial tests whether dexmedetomidine can help calm agitation caused by delirium in adults receiving palliative (comfort-focused) care. It may help reduce restlessness and distress when standard approaches may not be enough.
Calgary, AlbertaAges 18 years+ - NCT05025605RecruitingPhase 1
Study medicine for agitation in youth with bipolar or schizophrenia
This Phase 1 trial tests whether BXCL501 is safe and can help reduce agitation in children and teens who have bipolar disorder or schizophrenia. You may be considered if your agitation is significant during screening, but certain recent medication and health factors can make you ineligible.
Anaheim, CaliforniaAges 10–17 - NCT05431595RecruitingPhase 2/Phase 3
Test a less sedating plan for agitated delirium in cancer
This study looks at whether using certain sleep/behavior medicines (called neuroleptics) with anti-seizure medicines can calm agitation from delirium without needing as much of the usual “neuroleptic” medicines. It may help people with advanced cancer who are confused and very restless or hard to settle.
Houston, TexasAges 18 years+ - NCT05541276RecruitingPhase 3
Melatonin to prevent agitation and confusion after surgery in kids
This trial tests whether giving melatonin before surgery can reduce troublesome agitation and confusion as children wake up from anesthesia. It may help some kids have a calmer, safer recovery.
Copenhagen, Capital RegionAges 1–6 - NCT05632419Recruiting
Study of extreme agitation and what it predicts
This trial looks at people who show “extreme agitation” in order to better predict what may happen next. It mainly involves observation to understand the possible causes and likely outcomes of severe agitation.
Bobigny, Île-de-France RegionAges 18 years+ - NCT05636748Recruiting
Study how blood clots affect stroke, using special scans
This study looks at how blood clots form and contribute to an acute ischemic (clot-related) stroke. It uses PET-CT scanning to better understand the process and may help improve how future stroke treatments are targeted.
EdinburghAges 18 years+ - NCT05765162Recruiting
Research study on safer, more tailored anesthesia
This study looks at safer anesthesia—meaning medicines used during procedures—using a more personalized approach. It may help make anesthesia safer for adults having medical procedures.
Nykøbing FalsterAges 18–100
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Common questions
- Are there clinical trials for agitation?
- Yes. Clin2 currently lists 57 recruiting agitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a agitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a agitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.