Clinical trials
Agitation clinical trials
Below are recruiting agitation clinical trials, each written for real people, not researchers. We’re tracking 52 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07435675Recruiting
Nerve block to prevent agitation after ear surgery in children
This study tests if a nerve block behind the ear can help children ages 5–14 stay calm and comfortable after middle ear surgery. It may reduce confusion and restlessness when waking up from anesthesia.
Al Fayyum, Faiyum GovernorateAges 5–14 - NCT06938347RecruitingPhase 3
New contrast agent for heart ultrasound to detect shunts
This trial tests a new contrast agent (ASI-02) compared to a standard saline solution for people who need a heart ultrasound to detect a right-to-left shunt. It may help provide clearer images so doctors can make a better diagnosis.
Chicago, IllinoisAges 18 years+ - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT07568093Recruiting
Music therapy to reduce agitation after abdominal surgery
This study tests whether listening to music after abdominal surgery can help reduce agitation and anxiety during recovery. Researchers will compare patients who receive music therapy with standard care to see if it improves comfort and outcomes.
Hanover, Lower SaxonyAges 18 years+ - NCT07552896Recruiting
Screen Time and Recovery Confusion After Children's Surgery
This study looks at whether the amount of time children spend on screens (phones, tablets, TV) before surgery affects confusion and agitation as they wake up from anesthesia. Researchers want to understand this connection to help reduce distressing wake-up experiences.
Istanbul, IstanbulAges 2–11 - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years - NCT07534956Recruiting
Anesthesia Methods and Waking Up Agitation in Children
This study compares different anesthesia approaches to see which one helps children wake up more calmly after urogenital surgery (surgery on the urinary or reproductive system). Researchers want to find the best way to reduce agitation and confusion as children wake up from anesthesia.
IstanbulAges 3–10 - NCT07536568Recruiting
Caffeine to speed recovery after eye surgery in older adults
This study tests whether a small dose of caffeine placed under the tongue helps older adults wake up faster and feel less confused after eye surgery under general anesthesia. Researchers want to see if this simple approach can improve how quickly patients recover and reduce post-surgery agitation.
CairoAges 65 years+ - NCT06752616RecruitingPhase 2/Phase 3
Study on calming severe agitation in psychiatric emergency rooms
This trial tests two different medications to quickly calm severe agitation in people admitted to a psychiatric emergency room. You may be able to join if you are extremely agitated and need urgent medication to help you settle down.
Copenhagen NAges 18–64 - NCT07523438Recruiting
Nasal Medication to Reduce Agitation After Eye Surgery in Young Children
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
AlexandriaAges 3–6 - NCT07510516Recruiting
Verbal reminders to reduce confusion after anesthesia
This study tests whether giving a simple verbal reminder (like telling you where you are) after anesthesia can help reduce confusion or agitation when waking up. It is for adults having laparoscopic abdominal surgery under a specific inhaled anesthetic.
Lahore, Punjab ProvinceAges 18–70 - NCT07424807Recruiting
Comparing two needle techniques in chest lymph node biopsy
This trial compares two different ways of moving the needle during an EBUS-TBNA procedure to see which method gets better tissue samples from enlarged lymph nodes in the chest. It may help doctors improve the accuracy of diagnosis for conditions like lung cancer or infection.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07389135Recruiting
Heart rate and anxiety after nose surgery study
This study looks at whether your heart rate patterns and anxiety levels before surgery can predict how you will wake up after nose surgery (septorhinoplasty). If you are scheduled for this surgery, they will measure your heart rate and ask you questions about anxiety to see if these can help reduce confusion or agitation when you wake up.
Konya, KaratayAges 18–65 - NCT07375342Recruiting
Melatonin for calming children after tonsil removal
This trial tests whether giving melatonin before surgery can help children be less agitated and confused when waking up from anesthesia after tonsil removal. If it works, it could make the recovery smoother for both children and parents.
BanhāAges 4–10 - NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Tanta, El-GharbiaAges 3–7 - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT07243990Recruiting
Monitoring brain activity to reduce post-anesthesia confusion in kids
This trial tests if using a brain monitor during anesthesia can help lessen agitation in children after surgery. If your child is 6-12, generally healthy, and having a non-emergency surgery, this might be relevant.
SakaryaAges 6–12 - NCT06451952Recruiting
Virtual darkness therapy for agitation in dementia
This trial tests whether virtual darkness therapy (sitting in a dim, calming environment) can reduce agitation in people with dementia. It is designed for patients at NKS Olaviken hospital who have significant agitation.
Askøy, ErdalAges 50 years+ - NCT07144007Recruiting
Preventing agitation after rhinoplasty with propofol and dexmedetomidine
This study tests whether giving two medicines, propofol and dexmedetomidine, during rhinoplasty can help prevent confusion or restlessness when waking up from anesthesia. It may be a good option if you are having nose surgery and are generally healthy.
Van, TuşbaAges 18–65 - NCT06937229RecruitingPhase 3
Long-term study of KarXT for agitation in Alzheimer's
This trial tests if KarXT, taken with KarX-EC, is safe and effective for long-term treatment of agitation in Alzheimer's disease. It is for people who already completed a previous KarXT study.
Chandler, ArizonaAges 55–90 - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT05522647Recruiting
Study of risk behaviors in hospitalized confused or agitated patients
This is a study that observes how often and what kinds of “risk behaviors” happen in neurosurgery patients who are agitated or confused. It aims to better understand these behaviors so care can be improved for people who are unable to move or who seem restless.
Clermont-FerrandAges 18 years+ - NCT06817330Recruiting
Music therapy after ECT for depression
This trial tests if listening to music after electroconvulsive therapy (ECT) helps reduce confusion or agitation. It may help people being treated for depression feel calmer after their procedure.
RotterdamAges 18 years+ - NCT06803823RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's
This study tests an experimental drug, ONO-2020, to see if it can help reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, pacing, or verbal outbursts, and this trial aims to find a new treatment option.
AichiAges 55–90
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Agitation trials by city
Studies with a site in or near these metro areas.
Agitation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for agitation?
- Yes. Clin2 currently lists 52 recruiting agitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a agitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a agitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.