Clinical trials
Agitation clinical trials
Below are recruiting agitation clinical trials, each written for real people, not researchers. We’re tracking 57 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06938347RecruitingPhase 3
New contrast agent for heart ultrasound to detect shunts
This trial tests a new contrast agent (ASI-02) compared to a standard saline solution for people who need a heart ultrasound to detect a right-to-left shunt. It may help provide clearer images so doctors can make a better diagnosis.
Chicago, IllinoisAges 18 years+ - NCT07435675Recruiting
Nerve block to prevent agitation after ear surgery in children
This study tests if a nerve block behind the ear can help children ages 5–14 stay calm and comfortable after middle ear surgery. It may reduce confusion and restlessness when waking up from anesthesia.
Al Fayyum, Faiyum GovernorateAges 5–14 - NCT07389135Recruiting
Heart rate and anxiety after nose surgery study
This study looks at whether your heart rate patterns and anxiety levels before surgery can predict how you will wake up after nose surgery (septorhinoplasty). If you are scheduled for this surgery, they will measure your heart rate and ask you questions about anxiety to see if these can help reduce confusion or agitation when you wake up.
Konya, KaratayAges 18–65 - NCT06937229RecruitingPhase 3
Long-term study of KarXT for agitation in Alzheimer's
This trial tests if KarXT, taken with KarX-EC, is safe and effective for long-term treatment of agitation in Alzheimer's disease. It is for people who already completed a previous KarXT study.
Chandler, ArizonaAges 55–90 - NCT06808984RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's disease
This trial tests an investigational drug called BMS-986368 to see if it can safely reduce agitation in people with Alzheimer's disease. You may be able to join if you have Alzheimer's with confirmed biomarkers and experience agitation that has been going on for at least 4 weeks.
Homewood, AlabamaAges 55–90 - NCT06817330Recruiting
Music therapy after ECT for depression
This trial tests if listening to music after electroconvulsive therapy (ECT) helps reduce confusion or agitation. It may help people being treated for depression feel calmer after their procedure.
RotterdamAges 18 years+ - NCT07536568Recruiting
Caffeine to speed recovery after eye surgery in older adults
This study tests whether a small dose of caffeine placed under the tongue helps older adults wake up faster and feel less confused after eye surgery under general anesthesia. Researchers want to see if this simple approach can improve how quickly patients recover and reduce post-surgery agitation.
CairoAges 65 years+ - NCT07424807Recruiting
Comparing two needle techniques in chest lymph node biopsy
This trial compares two different ways of moving the needle during an EBUS-TBNA procedure to see which method gets better tissue samples from enlarged lymph nodes in the chest. It may help doctors improve the accuracy of diagnosis for conditions like lung cancer or infection.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT06803823RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's
This study tests an experimental drug, ONO-2020, to see if it can help reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, pacing, or verbal outbursts, and this trial aims to find a new treatment option.
AichiAges 55–90 - NCT06651567RecruitingPhase 2
Study of ITI-1284 for agitation in Alzheimer's
This trial tests an experimental drug called ITI-1284 to see if it can reduce agitation in people with Alzheimer's disease. It may help if you or your loved one experiences significant agitation related to Alzheimer's.
Anaheim, CaliforniaAges 55 years+ - NCT06451952Recruiting
Virtual darkness therapy for agitation in dementia
This trial tests whether virtual darkness therapy (sitting in a dim, calming environment) can reduce agitation in people with dementia. It is designed for patients at NKS Olaviken hospital who have significant agitation.
Askøy, ErdalAges 50 years+ - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT07534956Recruiting
Anesthesia Methods and Waking Up Agitation in Children
This study compares different anesthesia approaches to see which one helps children wake up more calmly after urogenital surgery (surgery on the urinary or reproductive system). Researchers want to find the best way to reduce agitation and confusion as children wake up from anesthesia.
IstanbulAges 3–10 - NCT07552896Recruiting
Screen Time and Recovery Confusion After Children's Surgery
This study looks at whether the amount of time children spend on screens (phones, tablets, TV) before surgery affects confusion and agitation as they wake up from anesthesia. Researchers want to understand this connection to help reduce distressing wake-up experiences.
Istanbul, IstanbulAges 2–11 - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age - NCT07375342Recruiting
Melatonin for calming children after tonsil removal
This trial tests whether giving melatonin before surgery can help children be less agitated and confused when waking up from anesthesia after tonsil removal. If it works, it could make the recovery smoother for both children and parents.
BanhāAges 4–10 - NCT04516057RecruitingPhase 3
Tested medicine nabilone for agitation in Alzheimer’s dementia
This Phase 3 trial studies whether nabilone can reduce agitation (restlessness, anger, or difficult behavior) in people with Alzheimer’s dementia. It’s designed for older adults who already have agitation despite standard dementia care.
Calgary, AlbertaAges 55 years+ - NCT05397639RecruitingPhase 3
Masupirdine trial for agitation in Alzheimer’s dementia
This Phase 3 study tests masupirdine to see if it can reduce agitation in people with Alzheimer’s-type dementia. If you have Alzheimer’s dementia with confirmed agitation, joining could help researchers find better treatment options.
Anaheim, CaliforniaAges 50–90 - NCT05522647Recruiting
Study of risk behaviors in hospitalized confused or agitated patients
This is a study that observes how often and what kinds of “risk behaviors” happen in neurosurgery patients who are agitated or confused. It aims to better understand these behaviors so care can be improved for people who are unable to move or who seem restless.
Clermont-FerrandAges 18 years+ - NCT05543681RecruitingPhase 2
Study drug for agitation in Alzheimer’s dementia with caregiver support
This Phase 2 trial tests a study medicine to reduce “agitation” behaviors in people with Alzheimer’s dementia. You and your caregiver would complete required assessments and may need genetic and blood testing to check how the body handles the drug.
Maitland, FloridaAges 60 years+ - NCT05783505Recruiting
Program to calm ICU patients and reduce restraints
This study tests a multi-step program to prevent and lessen agitation in ICU patients, with the goal of reducing the need for physical restraints. It also aims to improve comfort and safety during a longer ICU stay.
AlkmaarAges 18 years+ - NCT06539013Recruiting
Remifentanil for preventing agitation after rhinoplasty
This trial tests if a drug called remifentanil can help prevent confusion or restlessness when waking up from anesthesia after rhinoplasty (nose surgery). It may help you wake up more calmly.
Diyarbakır, KayapınarAges 18–70 - NCT06543134Recruiting
Body temperature and waking confusion after surgery
This study looks at how getting cold during surgery (hypothermia) might affect how confused or restless you feel when waking up from anesthesia. Researchers want to find ways to prevent these side effects and make your recovery smoother.
Kocaeli, IzmitAges 18–65 - NCT06752616RecruitingPhase 2/Phase 3
Study on calming severe agitation in psychiatric emergency rooms
This trial tests two different medications to quickly calm severe agitation in people admitted to a psychiatric emergency room. You may be able to join if you are extremely agitated and need urgent medication to help you settle down.
Copenhagen NAges 18–64
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Agitation trials by city
Studies with a site in or near these metro areas.
Agitation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for agitation?
- Yes. Clin2 currently lists 57 recruiting agitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a agitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a agitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.