Clinical trials
Amputation, Traumatic clinical trials
Below are recruiting amputation, traumatic clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06433648Recruiting
Powered knee study for above-knee amputee walkers
This study looks at how a powered (motorized) prosthetic knee joint affects walking in people with one above-knee amputation. It aims to find out if the powered knee makes walking easier or more natural.
Chicago, IllinoisAges 18–95 - NCT07011420Recruiting
Testing different prosthetics controls for arm amputees
This trial tests how different numbers and types of muscle signals (myoelectric) affect control of a prosthetic hand and wrist. It aims to find the best setup for people with a below-elbow amputation who have used a myoelectric prosthetic before.
Chicago, IllinoisAges 18 years+ - NCT07175675Recruiting
Surgery versus dressing for single finger amputations
This trial compares two treatments for a single finger amputation: surgery (reattachment) versus a special dressing that protects the wound while it heals on its own. It is for adults who are able to communicate in Finnish.
TampereAges 18 years+ - NCT06194838Recruiting
Mechanical vs. powered knee for above-knee amputees
This study compares a non-powered (mechanical) knee to a powered (battery-assisted) knee for people with above-knee amputations who walk at a moderate level (K2). It will help find out which knee type works better for your daily activities and mobility.
Austin, TexasAges 18 years+ - NCT05768802Recruiting
Testing a forearm implant that records muscle signals for prosthetic use
This study tests a small implant that records signals from your forearm muscles in people with a specific type of arm amputation. It aims to help improve how well prosthetic hands can be controlled using muscle activity.
Pittsburgh, PennsylvaniaAges 22–70 - NCT06737770Recruiting
Bone-anchored leg implant study
This study tests a bone-anchored implant (directly attached to the thighbone) for people with a single leg amputation above the knee. It aims to see if this implant helps with pain, movement, and skin issues caused by a traditional socket prosthetic.
BolognaAges 18–65 - NCT02395497RecruitingPhase 2/Phase 3
Penile transplant trial using immune-suppressing medicines
This study tests whether a donated penis can be successfully transplanted using medicines that calm the immune system to prevent rejection. It also looks at safety and recovery of function in men with severe penile loss from injury, cancer surgery, or birth conditions.
Baltimore, MarylandAges 18–69 - NCT06501092Recruiting
Study of the Point Mini prosthetic hand for children
This study tests a new type of prosthetic hand device called the Point Mini. It is designed for children and teens who have partial hand differences, and aims to see how well it works in everyday use at home.
Lafayette, ColoradoAges 3–17 - NCT06937242Recruiting
Testing a smarter prosthetic knee for safer walking
This study tests whether a microprocessor-controlled knee can reduce falls in people who walk limited distances. If you use a regular mechanical knee and have a moderate activity level, this trial might help you walk more safely.
Austin, TexasAges 18 years+ - NCT07384689Recruiting
Study of leg tissue in non-traumatic amputation patients
This study looks at the tissue environment in the legs of patients who need amputation due to non-traumatic causes, like poor blood flow or infection. Understanding the tissue better might help improve healing for future patients.
Aarhus NAges 18 years+ - NCT03995238Recruiting
Gait training for veterans with leg amputations
This study tests a walking rehabilitation plan to improve how you walk after a lower-leg amputation. It may help if your walking steps are uneven and you have diabetes and/or circulation problems in your legs.
Aurora, ColoradoAges 40–89 - NCT05929508Recruiting
Rebuilding leg strength after above-knee amputation
This study tests a new approach to improve walking ability and leg function after an above-knee (transfemoral) amputation. It may help by targeting muscle loss and supporting safer, stronger mobility over time.
Chicago, IllinoisAges 18 years+ - NCT06921707Recruiting
WounDx test for healing decisions in large wounds
This trial tests a new tool called WounDx that helps doctors decide the best way to treat large wounds on arms, legs, or buttocks. It may help your wound heal better by guiding your care.
Birmingham, AlabamaAges 18–65 - NCT04725201RecruitingPhase 4
IV heparin study after finger or hand reattachment
This study looks at whether giving an IV blood thinner called unfractionated heparin after finger/hand reattachment and restoring blood flow improves healing and safety. If you were accepted into the CEVARMU replant/revascularization program, this trial may be testing a standard-after-surgery medicine approach.
Montreal, QuebecAges 14 years+ - NCT02994160Recruiting
DEFT hand control test for people with arm amputations
This study tests a special implanted system meant to help control a hand using nerve signals. It is for adult arm/hand amputees and may help improve hand/arm control and reduce pain impacts.
Dallas, TexasAges 18–95 - NCT02797457Recruiting
Evaluating outcomes of donated hand and forearm transplants
This trial looks at whether donated (allograft) hand and forearm transplants are worth it compared with artificial devices, including cost and real-world results. It is meant for adults with amputations of both forearms who may be medically and psychologically able to receive the transplant.
BerckAges 18–60 - NCT06636136Recruiting
Bone-anchored implant for below-knee amputation
This trial tests a metal implant that connects directly to your shin bone, replacing the need for a socket. It's for people with below-knee amputations who have trouble using a regular prosthetic leg.
Bethesda, MarylandAges 22–65 - NCT03400345Recruiting
Follow-up for transplanted arm patients
This study follows people who received a transplanted arm (or both arms) to learn from their ongoing care. You may be asked for small tissue samples (biopsies) and to continue an immunotherapy plan to help protect the transplant.
Baltimore, MarylandAges 18–100 - NCT01459107RecruitingPhase 2
Upper arm transplant study using immune treatment
This trial tests replacing a missing or non-working lower arm/hand with a donated upper limb (transplant). It also uses a special immune treatment plan and bone marrow infusion to help the body accept the new limb, aiming to improve hand function and quality of life.
Baltimore, MarylandAges 18–69 - NCT07706452Recruiting
Balance Training for People with a Prosthetic Leg
This study tests a special balance training program for people who use a prosthetic leg after losing a leg due to injury. The program combines balance exercises with a second task (like talking or counting) to improve walking and stability in daily life.
Gaza, Gaza StripAges 18 years+ - NCT07432685Enrolling by invitation
Can movement predict chronic pain after combat limb injuries?
This study is looking for people with combat-related arm or leg injuries to see if how they move can predict long-term pain. Researchers hope to better understand who might develop chronic pain and help improve treatment.
LvivAges 18–50
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Amputation, Traumatic trials by city
Studies with a site in or near these metro areas.
Amputation, Traumatic trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for amputation, traumatic?
- Yes. Clin2 currently lists 21 recruiting amputation, traumatic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a amputation, traumatic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a amputation, traumatic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.