Clinical trials
ARDS (Moderate or Severe) clinical trials
Below are recruiting ards (moderate or severe) clinical trials, each written for real people, not researchers. We’re tracking 1,471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04046237Recruiting
Treating gum disease to study heart artery inflammation after a heart attack
This study tests whether treating severe gum disease in people who recently had a heart attack can reduce inflammation in the artery plaque. It may help researchers understand if gum treatment could benefit heart health after a heart attack.
ParisAges 30–70 - NCT06152107Recruiting
BTVA Treatment for Severe Emphysema Study
This study tests a new bronchoscopic treatment called BTVA for people with severe emphysema. It uses heat to shrink damaged parts of the lung to improve breathing.
Zhengzhou, HenanAges 18 years+ - NCT06513949RecruitingPhase 2
Testing IC14 for ARDS on a ventilator
This trial tests a new treatment called IC14 for people in the hospital on a breathing machine for ARDS (a severe lung injury). The study aims to see if IC14, which blocks a protein involved in inflammation, can help the lungs heal faster.
Seattle, WashingtonAges 18 years+ - NCT06472310Recruiting
Study of severe asthma in Russia (CORSAR)
This study looks at the health records of people in Russia with severe, uncontrolled asthma to understand their symptoms and treatments better. It does not involve any new medicine or treatment.
AstrakhanAges 18 years+ - NCT03321370Recruiting
Study of brain swelling after severe head injury surgery
This trial looks at changes in brain activity after severe traumatic brain injury (TBI) when patients need emergency skull surgery. The goal is to better understand what happens in the brain after surgery and whether earlier recognition could help care after injury.
Minneapolis, MinnesotaAges 18 years+ - NCT06456450Recruiting
Taiwan severe asthma biologic registry study
This study is creating a registry to track the long-term safety and effectiveness of biologic treatments for severe asthma in Taiwan. If you are taking a biologic like omalizumab, mepolizumab, or benralizumab, joining this registry helps doctors learn how well these medicines work over time.
TaichungAges 18 years+ - NCT06441305Recruiting
Treating severe malnutrition in Kenyan children
This study looks at whether community health workers can help more children with severe acute malnutrition get treated. If your child is 6 months to 5 years old and has severe malnutrition, they may be able to join.
LodwarAges 6 months–5 years - NCT06412497RecruitingPhase 2
Stem cell transplant for aplastic anemia and bone marrow failure
This trial tests a stem cell transplant using a milder conditioning regimen and a drug called post-transplant cyclophosphamide to treat severe aplastic anemia and other acquired bone marrow failure conditions. The goal is to help patients achieve a functioning donor bone marrow with fewer side effects.
Minneapolis, MinnesotaAges birth–75 years - NCT06380504Recruiting
Increasing severe malnutrition treatment in Ethiopia
This trial tests ways to help more children with severe acute malnutrition (SAM) get treatment in Ethiopia. If your child has SAM or is already in a SAM treatment program, they may be eligible.
JimmaAges 6 months–5 years - NCT05536219Recruiting
Study how autoantibodies affect virus levels in severe lung infections
This study measures blood immune “autoantibodies” that may affect how much virus is in the body during severe respiratory infections. It may help doctors understand which patients are more likely to have higher virus levels and could guide future treatment choices.
Bron, RhoneAges Any age - NCT06189963RecruitingPhase 1/Phase 2
Cell therapy trial for moderate Alzheimer's disease
This trial tests a new immune cell therapy (SNK01) for people with moderate Alzheimer's disease. The goal is to see if it can slow down memory and thinking decline.
Glendale, CaliforniaAges 40–85 - NCT05920109Recruiting
Early pain block to help breathing after severe chest trauma
This study tests whether an early pain-numbing injection to the chest wall can reduce how much ventilator support (breathing machine) people need after severe blunt chest injury with multiple rib fractures. If it works, it may help patients breathe more easily and spend less time on ventilation in the ICU.
BordeauxAges 18 years+ - NCT06010719RecruitingPhase 4
Azithromycin for severe malnutrition in children
This study tests whether adding the antibiotic azithromycin to standard nutritional care helps young children with severe acute malnutrition recover better. It is for children aged 6 to 59 months in Burkina Faso who have uncomplicated malnutrition and are not currently on antibiotics.
Nouna, KossiAges 6 months–4.9 years - NCT06119516Recruiting
Guiding breathing machine settings for severe obesity and lung injury
This study tests a new way of setting the breathing machine for people with severe obesity and lung injury (ARDS). It aims to measure pressure inside the lungs more directly, which could help customize ventilation and improve outcomes.
AngersAges 18 years+ - NCT05975398Recruiting
Study of severe spontaneous brain bleeding in China
This study looks at people with a severe type of brain bleed that happens on its own (not from an injury). It compares different treatments to find the best way to help patients recover.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05820516Recruiting
Study of a valve treatment for severe leaking tricuspid valve
This trial looks at a catheter-based procedure using the TricValve system for people with severe “tricuspid regurgitation” (a leaky tricuspid valve) who are very symptomatic. It may help reduce the backflow and improve heart function, especially for people who are too unwell for or not helped by standard options.
Pisa, PisaAges 18 years+ - NCT05678699Recruiting
How Medicaid programs affect serious pregnancy complications
This study looks at how Medicaid rules and programs affect serious health problems during pregnancy and after birth. It may include women on Medicaid and also doulas and health-plan leaders, to help improve care for mothers.
Pittsburgh, PennsylvaniaAges Any age - NCT05578742Recruiting
Test breathing support patterns in moderate to severe ARDS
This trial studies how adjusting ventilator settings can better match the lungs’ ability to move air and oxygen in people with moderate to severe ARDS. It may help doctors tailor breathing support for different “lung mechanics” patterns, especially during the first days after intubation.
Angers, Maine et LoireAges 18 years+ - NCT05666960RecruitingPhase 1
Study drug R-3750 for mild to moderate ulcerative colitis
This Phase 1 study tests whether R-3750 is safe in people with mild to moderate ulcerative colitis and looks for early signs it could help. You may be able to join if you have stable treatment, confirmed diagnosis, and meet several health and medication timing rules.
Valencia, CaliforniaAges 18–65 - NCT05304728Enrolling by invitation
Hospital sepsis decision support program enrollment study
This study tests a computer system meant to help doctors recognize and manage sepsis (a serious body-wide response to infection) when people come to the emergency department or are admitted to the hospital. If you’re evaluated in a hospital setting for possible sepsis, you may be included to help improve care decisions.
Irvine, CaliforniaAges 18–89 - NCT05234463Recruiting
Study links complement activity to IgA kidney disease severity
This study looks at how parts of the immune system (called complement) may relate to how severe IgA kidney disease is. It may help doctors understand disease activity better, even if the study is mainly observational.
StrasbourgAges 18 years+ - NCT05075161RecruitingPhase 3
Pirfenidone to help prevent lung scarring in ARDS
This Phase 3 trial tests whether pirfenidone can prevent or reduce lung scarring (fibrosis) in adults with ARDS who are within about a week of their illness starting. It may help by lowering harmful inflammation and the body’s scarring response.
Milan, MIAges 18 years+ - NCT05071222RecruitingPhase 1/Phase 2
Gene therapy trial for Artemis SCID using modified blood cells
This trial tests whether gene therapy can safely and effectively treat children with a specific type of severe combined immunodeficiency (SCID) caused by an Artemis gene problem. It uses the patient’s own stem cells, modifies them to add a missing gene, and then returns them after chemotherapy to help the new cells work.
ParisAges Up to 3.9 years
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Common questions
- Are there clinical trials for ards (moderate or severe)?
- Yes. Clin2 currently lists 1,471 recruiting ards (moderate or severe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ards (moderate or severe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ards (moderate or severe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.