Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 450 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07651215Enrolling by invitation
Short-Stem Shoulder Replacement Surgery Outcomes Study
This study looks at how well a newer type of shoulder replacement surgery works. Researchers are checking X-rays and patient function for people who had this specific short-stem surgery at least 2 years ago.
LinzAges 18 years+ - NCT06308965Recruiting
Does blood vessel-sparing hip replacement improve recovery?
This study compares two different surgical techniques for total hip replacement using an anterior approach. The goal is to see if saving the small blood vessels around the hip during surgery leads to a better recovery for patients.
Genk, LimburgAges 18 years+ - NCT07630896RecruitingPhase 4
Prednisone and blood sugar monitoring after knee or hip replacement
This study looks at how a common steroid medicine, prednisone, affects blood sugar after knee or hip replacement surgery. It aims to find the best way to manage blood sugar for a smoother recovery.
New York, New YorkAges 18 years+ - NCT07630337Recruiting
Cryotherapy to reduce pain medication after knee replacement
This study tests whether applying cold therapy (cryotherapy) after knee replacement surgery helps patients need fewer opioid pain medications than standard care alone. If cryotherapy works, it could help you manage pain more safely after surgery.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07634523RecruitingPhase 4
Amino acids to prevent muscle loss after knee surgery
This study tests whether a supplement containing branched chain amino acids (special protein building blocks) can help prevent muscle loss in older adults having knee replacement surgery. The goal is to help patients recover strength and mobility more quickly after their operation.
Seongnam-si, Gyeonggi-doAges 40–100 - NCT07606794Recruiting
Hip Surgery Pain Relief Using Nerve Blocks
This study tests two types of nerve-blocking injections to reduce pain after hip replacement surgery. The injections numb specific nerves around your hip so you need less pain medication after the operation.
Tanta, El-GharbiaAges 18–75 - NCT06152198Recruiting
Hip surgery comparison for nondisplaced femoral neck fracture
This trial compares two types of surgery—plates and screws versus hip replacement—for a specific type of hip fracture that is not shifted out of place. The goal is to see which option helps people recover better.
UppsalaAges 75 years+ - NCT07601906Recruiting
Blood Flow Exercise Therapy After Knee Replacement Surgery
This study tests whether special exercises that temporarily reduce blood flow to your leg can help you recover better after knee replacement surgery. It focuses on reducing pain and improving your ability to bend and straighten your knee.
Lahore, Punjab ProvinceAges 50–65 - NCT07589127Recruiting
Nerve Block for Pain Relief During Knee Replacement
This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.
Hjelset, Møre og RomsdalAges 18–80 - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT07561333Recruiting
Pain Relief Methods for Knee Replacement Surgery
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
Çorum, CentreAges 18–80 - NCT07543796RecruitingPhase 2
Pain Relief After Hip Replacement Surgery
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Guangzhou, GuangdongAges 18–80 - NCT07544264Recruiting
Five-Year Knee Replacement Outcomes Study
This study follows patients who receive a new knee joint replacement for severe knee arthritis or similar conditions. Researchers will track how well the artificial knee works and how patients recover over 5 years to ensure the replacement lasts and improves quality of life.
BolognaAges 50–85 - NCT07545447Recruiting
AI-guided knee surgery education to reduce anxiety and fear
This trial tests whether using an AI-assisted 3D visualization of your knee before surgery can reduce anxiety and fear of movement (kinesiophobia) after knee replacement. You would receive extra visual education along with standard care to see if it helps you feel less stressed and more confident about moving after surgery.
Elâzığ, UlukentAges 55 years+ - NCT07550647Recruiting
Early Rehab Program After Hip Replacement Surgery
This study tests a rehabilitation program that starts soon after hip replacement surgery for arthritis or hip developmental issues. The program uses telehealth (video calls) to help you recover strength and mobility at home.
Niğde, MerkezAges 50–75 - NCT07539467Enrolling by invitation
Nerve Block and Tourniquet for Knee Surgery Pain Relief
This trial tests whether a nerve block (numbing injection near the thigh) combined with a tourniquet (pressure cuff) after knee replacement surgery reduces pain better than standard care. If it works, it could help patients recover more comfortably with less need for strong pain medications.
AnkaraAges 40–85 - NCT07537036Recruiting
Pain Relief Methods for Hip Replacement Surgery
This trial compares two nerve-blocking techniques to reduce pain after hip replacement surgery. Both methods use numbing medication around specific areas near your hip to help you feel more comfortable after the operation.
Tanta, El-GharbiaAges 18 years+ - NCT07520721Recruiting
Shoulder Replacement Materials: Plastic vs Hybrid Implants
This trial compares two types of shoulder replacement implants for people with long-standing shoulder arthritis. It tests whether a hybrid design (combining different materials) works better than a traditional plastic design for pain relief and shoulder function.
Hoofddorp, North HollandAges 18 years+ - NCT07511985Recruiting
Managing Pain After Knee Replacement Surgery
This study looks at how "rebound pain" (increased pain when pain medication wears off) affects long-term pain after total knee replacement. Researchers want to understand this connection and potentially improve pain management strategies for knee surgery patients.
Konya, MeramAges 18 years+ - NCT07489963Recruiting
Does keeping the posterior cruciate ligament help after knee replacement?
This trial compares two ways of doing robotic-assisted knee replacement: one that keeps the posterior cruciate ligament (a natural knee stabilizer) and one that doesn't. Researchers will see if saving the ligament leads to better knee function a year after surgery.
BordeauxAges 18 years+ - NCT06611319RecruitingPhase 3
Shorter blood thinner after hip replacement: a recovery study
This study tests a shorter course of blood thinner medication (rivaroxaban) after hip replacement surgery, following an enhanced recovery plan. It aims to see if a shorter treatment can safely prevent blood clots and help you recover faster.
Linz, Upper AustriaAges 18–85 - NCT07477730Recruiting
Pain Relief Options for Knee Replacement Surgery
This study compares two ways to manage pain after knee replacement surgery: local numbing medicine injected into the knee versus numbing several nerves in the leg. The goal is to find which method provides better pain control and recovery.
Toulouse, Haute-GaronneAges 18 years+ - NCT07465159Recruiting
Prehabilitation for frail patients before hip or knee replacement
This study tests whether a 'prehabilitation' program (tailored exercise and nutrition support before surgery) helps older patients who are frail recover better after hip or knee replacement. Participants will be randomly assigned to either the prehabilitation group or the usual care group.
ReykjavikAges 70 years+ - NCT07465484Recruiting
Total knee replacement for bow-leg deformity
This study looks at how well total knee replacement works for people who have severe knee arthritis and a bow-leg (varus) deformity. It may help you if you have a lot of knee pain and are considering surgery.
MoscowAges 18 years+
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 450 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.