Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 436 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07145957Recruiting
Pre-surgery exercise program for better shoulder rotation after replacement
This study tests if a special exercise program before shoulder replacement surgery improves how well you can rotate your arm inward after the operation. Participants do exercises for 6 weeks before surgery and are followed for 2 years.
Gainesville, FloridaAges 40–80 - NCT06848023Enrolling by invitation
Shoulder replacement vs tendon repair in older adults
This study compares how well two different shoulder surgeries—reverse total shoulder replacement and rotator cuff repair—work for people 60 and older, at least one year after the operation. If you meet the age and surgery requirements, your results could help doctors decide which procedure is better for older adults.
Germantown, TennesseeAges 60–95 - NCT04031820Recruiting
Comparing two hip cup types to prevent dislocation
This trial compares a “dual-mobility” hip cup to a “unipolar” hip cup during primary hip replacement, focusing on dislocation (the hip coming out of place) and overall cost-effectiveness. It may help your care team choose the best implant for you and monitor outcomes after surgery.
AmsterdamAges 70 years+ - NCT04049279Recruiting
Testing hip implant cement amount for better stability
This study compares hip implant “migration” (how the implant may slowly shift) when a cemented hip cup is used with different cement approaches. It may help surgeons choose the option that keeps the implant more stable over time.
AmsterdamAges 65 years+ - NCT04199780Recruiting
Brain stimulation plus education to reduce pain after joint surgery
This study tests whether a non-surgical brain stimulation treatment combined with a structured education program can reduce pain after knee or hip replacement surgery. It may help some people feel less pain and recover more comfortably.
Charleston, South CarolinaAges 18–90 - NCT04460989Recruiting
Compare knee replacement satisfaction by implant type
This study asks how satisfied people are after knee replacement, comparing different knee implant types. You may help researchers understand which implant approach leads to better patient experience.
LyonAges 18 years+ - NCT04848896Recruiting
Safety and outcomes study of a smart knee replacement
This trial studies whether a “smart” knee replacement system (CORI) is safe and works well for people getting a total knee arthroplasty (TKA). If you’re a good candidate for a cemented standard knee replacement, the study follows you for two years to check results after surgery.
EppingAges 18 years+ - NCT04868305Recruiting
Compare two surgery types for unstable hip fractures
This trial compares an intramedullary nail versus a hip replacement for unstable hip fractures. It may help guide which operation works best to restore walking and function after injury.
StavangerAges 65–120 - NCT04960098Recruiting
Survey after hip or knee replacement surgery
This study asks people who have had a hip or knee replacement to share how they’re doing over time. It’s testing whether patient-reported survey answers can help measure recovery and outcomes.
MilanAges 18 years+ - NCT05216666Recruiting
Surgery type and leftover limping after hip replacement
This study looks at whether the kind of hip surgery approach affects how much limping remains after a total hip replacement. You may benefit by helping researchers find the approach that leads to better walking after surgery.
MölndalAges 40–80 - NCT05227924Recruiting
Testing safety and performance of a hip implant device type
This study checks how safe and well a specific brand of hip implant (SYMBOL range) works in people getting a total hip replacement. It may help by confirming the device performs as expected for primary or revision surgeries.
BeaumontAges 18 years+ - NCT05701059Recruiting
Tests different artificial discs for neck nerve and spinal cord problems
This trial compares two types of artificial disc implants used for certain neck problems. It may help people who have tried non-surgical treatments but still have ongoing nerve symptoms or spinal cord issues from a damaged disc in the neck.
Los Angeles, CaliforniaAges 18–60 - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT05845021Recruiting
Screening and referral for bone health after hip or knee surgery
This study looks at a simple plan for surgeons to identify people with low bone strength (osteoporosis) and refer them for bone health care after hip or knee replacement surgery. It may help you get evaluated and treated earlier if you have osteoporosis.
Columbia, MarylandAges 50 years+ - NCT05981105Recruiting
Recovery and Chronic Pain After Knee Replacement
This study tests a special recovery program after knee replacement surgery to see if it helps reduce long-term pain. You may be eligible if you are having a first-time knee replacement for osteoarthritis, are between 18 and 65, and live near the hospital.
New York, New YorkAges 18–75 - NCT06083480RecruitingPhase 4
Reducing stress to prevent long-term pain after knee replacement
This trial tests if lowering oxidative stress (damage from natural body processes) during knee replacement surgery can prevent chronic pain afterward. It may help people with osteoarthritis who have moderate to severe pain before surgery.
Nashville, TennesseeAges 50 years+ - NCT06127719Recruiting
Surgery wait time and knee replacement quality of life
This study looks at how waiting for knee replacement surgery affects your quality of life. It may help doctors understand how to improve care for people waiting for surgery.
Hoorn, North HollandAges 18–100 - NCT06133920Recruiting
How long to immobilize after shoulder replacement for broken upper arm
This study compares different durations of immobilization (keeping the arm still) after a reverse total shoulder replacement for a broken upper arm. It aims to find the best approach for recovery.
Camden, New JerseyAges 60 years+ - NCT06152198Recruiting
Hip surgery comparison for nondisplaced femoral neck fracture
This trial compares two types of surgery—plates and screws versus hip replacement—for a specific type of hip fracture that is not shifted out of place. The goal is to see which option helps people recover better.
UppsalaAges 75 years+ - NCT06342843Recruiting
Comparing two ways to do hip replacement surgery
This trial compares two different surgical approaches for total hip replacement: the direct superior approach and the posterolateral approach. It aims to see which one leads to better recovery and outcomes for people with severe hip arthritis.
Breda, North BrabantAges 18–99 - NCT05097976RecruitingPhase 4
Medrol tablets to reduce pain after knee replacement
This trial tests whether a short course of Medrol (methylprednisolone) can improve recovery after outpatient total knee replacement done for osteoarthritis. You would be randomly assigned to receive Medrol or a comparison treatment.
Oak Brook, IllinoisAges 18 years+ - NCT06611319RecruitingPhase 3
Shorter blood thinner after hip replacement: a recovery study
This study tests a shorter course of blood thinner medication (rivaroxaban) after hip replacement surgery, following an enhanced recovery plan. It aims to see if a shorter treatment can safely prevent blood clots and help you recover faster.
Linz, Upper AustriaAges 18–85 - NCT06634654Recruiting
AI-guided knee replacement study
This trial tests whether using artificial intelligence can improve recovery from total knee replacement by tailoring care to your body's needs. It may help people with severe knee arthritis who have not had major knee surgery before.
Rome, ItalyAges 18 years+ - NCT06687109Recruiting
Joint replacement surgery registry study
This study collects information from people having joint replacement surgery to track how they do over time and improve care.
Spokane, WashingtonAges 18 years+
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 436 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.