Clinical trials
Atherosclerosis clinical trials
Below are recruiting atherosclerosis clinical trials, each written for real people, not researchers. We’re tracking 160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04537403RecruitingPhase 1
PET scan study of artery inflammation marker in plaque
This Phase 1 study tests whether a special PET scan can detect a specific inflammation signal (CCR2) in atherosclerosis—fatty plaque buildup in blood vessels. It may help future doctors better see which plaques are more inflamed and potentially more dangerous.
St Louis, MissouriAges 18–89 - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06230406Recruiting
Gene study in atherosclerosis patients having surgery
This study looks at genes in people who have atherosclerosis (hardening of the arteries). It will check tissue samples taken during surgery to learn more about how the disease works.
San Donato Milanese, MilanAges Any age - NCT05994014Recruiting
Comparing two heart scans for artery blockages
This study compares two types of heart scans to see which one better finds blockages in the arteries of people with chest discomfort or shortness of breath when active. You will have both a special CT scan and a PET/CT scan to check the health of your heart arteries.
Baltimore, MarylandAges 18 years+ - NCT05838547Recruiting
PET-MR scan study for narrowing in the carotid artery
This study tests how well a special PET-MR scan can help evaluate carotid artery plaque in people who have significant narrowing but no symptoms. It may help researchers better understand disease activity to guide treatment decisions like medication alone or medication plus surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05365438RecruitingPhase 4
Atorvastatin plus omega-3 for artery plaque in type 2 diabetes
This trial studies whether a combination of atorvastatin and omega-3 can reduce signs of artery plaque in people with type 2 diabetes and “mixed” cholesterol problems. It’s focused on people who don’t have symptoms from plaque yet.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT05365425RecruitingPhase 4
Choline fenofibrate to reduce plaque in type 2 diabetes
This trial studies whether choline fenofibrate can improve blood vessel plaque (carotid artery plaque) in people with type 2 diabetes and mixed cholesterol problems. It aims to see if the medicine can make carotid plaque thinner or otherwise healthier while keeping safety in mind.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT05235464Recruiting
Testing a high-protein diet for heart plaque risk
This study checks whether eating more protein affects atherosclerosis, which is plaque buildup in artery walls. It may help researchers understand if a high-protein approach changes health markers linked to heart disease.
Columbia, MissouriAges 45–75 - NCT03504956Recruiting
MRI study to map early heart artery plaque changes
This study uses an MRI scan to better “see and measure” early changes in the heart’s artery lining. It may help researchers understand coronary artery disease earlier, even before it causes symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT02381301Recruiting
Blood and heart CT scan tests for heart blood-flow markers
This study looks at whether certain lab “biomarkers” and a heart CT scan can help understand heart blood flow in people getting routine coronary CT angiography (CCTA). It may be useful for improving how doctors assess heart health from scan and blood results.
Maastricht, LimburgAges 18 years+ - NCT04098536Recruiting
Diesel exposure study of long-lasting inflammation and blood vessels
This study exposes healthy adults to diesel fumes to see how it affects inflammation (the body’s response to irritation) and blood vessels over time. It may help researchers understand health risks from diesel air pollution, though it is not for people with existing chronic health conditions.
Athens, AtticaAges 18–60 - NCT01384721Recruiting
CT scan study for heart artery disease risk
This study uses a CT heart scan (with a calcium score) to better understand risk in people with suspected coronary artery disease. You may be asked to have scan-based measurements and then be followed for at least a year.
Milan, MIAges 18 years+ - NCT04827498Recruiting
Testing heart blood-flow problems without clogged arteries
This study looks at how well the heart’s blood vessels work in people who have symptoms of reduced blood flow but no major artery blockage. It uses special heart tests with medicines to check how the vessels respond and may help guide better diagnosis and treatment.
MadridAges 18 years+ - NCT05550077Recruiting
Imaging study for narrowed brain arteries after stroke
This trial uses a detailed eye/brain imaging test (optical coherence tomography) to study people with significantly narrowed brain arteries after certain stroke-like events. It may help researchers better understand and monitor this condition to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05244629Recruiting
Compare two stents for chronic artery-related gut pain
This trial tests whether an uncovered stent or a covered stent works better for treating chronic mesenteric ischemia (reduced blood flow to the intestines from artery narrowing). It’s meant for adults with symptoms and scans showing significant narrowing in a specific gut artery.
København ØAges 18 years+ - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT05482399Recruiting
Study statin use and silent artery plaque in older adults
This study looks at “subclinical atherosclerosis,” meaning early or silent plaque buildup in the arteries, in older people already taking statins. It may help doctors understand how well statins can slow artery damage in people with multiple health conditions.
BernAges 70 years+ - NCT05932472RecruitingPhase 4
Compare taking aspirin in the morning vs bedtime
This trial studies whether taking your daily aspirin in the morning or at bedtime changes heart and circulation outcomes. It is meant to see if timing matters for people who already take aspirin every day.
HellerupAges 18 years+ - NCT04040777Recruiting
Cardiometabolic risk registry for adults
This study is a health registry that collects information about risk factors for heart and metabolic problems in adults. It may help doctors better understand who is at higher risk and guide future prevention strategies.
Pilar, Buenos AiresAges 18 years+ - NCT07837934RecruitingPhase 2
Colchicine to prevent heart disease in adults with type 2 diabetes
This trial tests whether a daily low-dose of colchicine, a common anti-inflammatory medicine, can help prevent heart attacks and strokes in people with type 2 diabetes who do not yet have heart disease. If it works, it could be a simple addition to your current diabetes care.
Singapore, SingaporeAges 21–80 - NCT07824921Enrolling by invitation
Oral microbiome in aorta aneurysm and carotid atherosclerosis
This study looks at how bacteria in your mouth might be linked to the health of your blood vessels. It may help doctors understand why some people get aneurysms or blocked arteries, and could lead to better ways to prevent or treat these conditions.
BudapestAges 18–110 - NCT06511089RecruitingPhase 3
Carotid artery stenting during stroke clot removal
This trial tests whether placing a stent in a narrowed carotid artery during a procedure to remove a stroke clot improves outcomes. If you have a stroke with a blocked large artery and significant carotid narrowing, this study may be relevant to you.
GroningenAges 18 years+
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Common questions
- Are there clinical trials for atherosclerosis?
- Yes. Clin2 currently lists 160 recruiting atherosclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atherosclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atherosclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.