Clinical trials
Atrial Fibrillation, Paroxysmal or Persistent clinical trials
Below are recruiting atrial fibrillation, paroxysmal or persistent clinical trials, each written for real people, not researchers. We’re tracking 469 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06953752Recruiting
Music during atrial fibrillation ablation under light sedation
This study tests whether listening to music during a common heart procedure for atrial fibrillation (called catheter ablation) can improve your experience while you are awake but relaxed. It may help you feel calmer and more comfortable.
Shaoxing, ZhejiangAges 18–80 - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT06938412Recruiting
Exercise and Fitbit for Afib patients
This study tests whether using a Fitbit activity tracker and a supportive exercise program helps people with AFib become more active. It may help you feel better and manage your heart rhythm.
New York, New YorkAges 18 years+ - NCT05427435Recruiting
Testing alcohol treatment of a heart vein during atrial fibrillation ablation
This study tests whether applying a small amount of alcohol to a specific heart vein (“vein of Marshall”) is safe and feasible during a standard atrial fibrillation (AF) ablation. It may help improve AF treatment, but the goal here is mainly to see if the approach can be done safely in the right patients.
PessacAges 18 years+ - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT06719921Enrolling by invitation
Catheter ablation for atrial fibrillation without x-ray
This study tests a way to perform catheter ablation for atrial fibrillation using a non-fluoroscopic lab, meaning no x-ray is needed during the procedure. It may help patients avoid radiation exposure.
Hangzhou, ZhejiangAges 18 years+ - NCT06716021RecruitingPhase 3
Etripamil for rapid heart rate in atrial fibrillation
This trial tests a medication called etripamil to see if it can quickly slow down a rapid heart rate during episodes of atrial fibrillation. It may help people who have frequent, long-lasting episodes with a fast heartbeat.
West Hills, CaliforniaAges 18 years+ - NCT06696079Recruiting
Early vs later blood thinner restart after brain bleed surgery in atrial fibrillation
This trial compares restarting a blood thinner early (within a few days) versus later (after about a week) in people who have a chronic subdural hematoma drained and also have atrial fibrillation. The goal is to find out which timing helps prevent both new bleeding and blood clots.
Oulu, North OstrobothniaAges 18 years+ - NCT06618417Recruiting
Home sleep test for sleep apnea in atrial fibrillation
This study is using a smartphone app and a home sleep test to see if checking for sleep apnea helps people with atrial fibrillation feel better and have fewer heart rhythm episodes. The goal is to make monitoring easier for you at home.
HellerupAges 18 years+ - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
HalifaxAges 18 years+ - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT06500988Recruiting
Smartphone app for atrial fibrillation and weight management
This study uses a smartphone app and activity tracker to help people with atrial fibrillation (an irregular heartbeat) and a higher body weight manage their condition through tailored exercise guidance.
Baltimore, MarylandAges 18 years+ - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT06067438RecruitingPhase 2
Amiodarone to Prevent Irregular Heartbeat After Esophageal Cancer Surgery
This trial tests if amiodarone, a medication that helps keep your heart rhythm steady, can prevent a type of irregular heartbeat called atrial fibrillation after surgery to remove part of your esophagus. If you are having this surgery (called minimally invasive esophagectomy or MIE) for cancer or other esophagus problems, you may be able to join.
Portland, OregonAges 18 years+ - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT05991700RecruitingPhase 1/Phase 2
Grape Powder to Prevent Irregular Heartbeat After Valve Surgery
This trial tests whether a grape powder supplement (rich in plant compounds called anthocyanins) can help prevent a common heart rhythm problem (atrial fibrillation) after mitral valve repair surgery. It is for people who are scheduled for this surgery and do not have certain heart or health issues.
Ann Arbor, MichiganAges 18–79 - NCT05955365RecruitingPhase 4
Single anticoagulant blood thinner after stent in atrial fibrillation
This trial tests whether taking a single “P2Y12 inhibitor” blood thinner (instead of multiple medicines) is safe and effective after you get a coronary stent. It’s for people with atrial fibrillation who need long-term blood thinning and have recently had a successful stent procedure.
HasseltAges 18 years+ - NCT05836987RecruitingPhase 3
Smartwatch-guided blood thinners for intermittent atrial fibrillation
This study tests whether using a smartwatch to monitor your heartbeat can safely guide when to take blood thinners. If you have intermittent atrial fibrillation, you may be able to avoid taking blood thinners when your heart rhythm is normal.
Phoenix, ArizonaAges 22–85 - NCT05434819Recruiting
Ablation study during heart surgery for atrial fibrillation
This trial looks at whether a special heart rhythm treatment called “ablation” works well when done during certain heart operations. It may help reduce atrial fibrillation (AF) symptoms or future abnormal rhythm episodes for people who are already having surgery.
Hamilton, OntarioAges 18 years+ - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT04685317Recruiting
Sentinel brain-protection device during atrial fibrillation ablation
This trial tests whether a specialized “brain protection” device can improve safety during atrial fibrillation (AF) catheter ablation. It may help reduce the risk of stroke or related complications while treating AF.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation, paroxysmal or persistent?
- Yes. Clin2 currently lists 469 recruiting atrial fibrillation, paroxysmal or persistent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation, paroxysmal or persistent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation, paroxysmal or persistent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.