Clinical trials
Atrial Fibrillation, Paroxysmal or Persistent clinical trials
Below are recruiting atrial fibrillation, paroxysmal or persistent clinical trials, each written for real people, not researchers. We’re tracking 469 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07641582Recruiting
Gene Testing to Predict Heart Rhythm Problems
This study uses a genetic test to identify who might develop atrial fibrillation (an irregular heartbeat) in the future. Researchers believe certain genetic patterns combined with health factors can help predict this condition early, which could lead to better prevention.
IncheonAges 20–79 - NCT07380620Enrolling by invitation
Step-by-step treatment for persistent atrial fibrillation
This trial tests a step-by-step treatment plan for people with persistent atrial fibrillation (a type of irregular heartbeat) who live in Southwest China. The goal is to find a better way to manage and possibly fix this heart condition.
ChongqingAges 18 years+ - NCT06719921Enrolling by invitation
Catheter ablation for atrial fibrillation without x-ray
This study tests a way to perform catheter ablation for atrial fibrillation using a non-fluoroscopic lab, meaning no x-ray is needed during the procedure. It may help patients avoid radiation exposure.
Hangzhou, ZhejiangAges 18 years+ - NCT05341986Enrolling by invitation
ED tool to help prevent stroke in atrial fibrillation
This study tests an electronic decision-support tool used in the emergency department (ED) to help clinicians choose the safest way to prevent stroke when atrial fibrillation is newly found. It may help by improving how quickly and consistently stroke-prevention treatment is considered.
Portland, OregonAges 18 years+ - NCT05539040Recruiting
Testing why certain heart signals trigger atrial fibrillation
This trial studies abnormal electrical signals in the right upper heart chamber and how they relate to atrial fibrillation (AF). It may help improve how doctors target AF treatment during catheter ablation for people who have AF symptoms.
LondonAges 18–85 - NCT05147792Recruiting
LAA closure study for people with atrial fibrillation
This trial tests a non-drug procedure to close a heart area called the left atrial appendage (LAA) to help prevent stroke in people with atrial fibrillation who are high risk. It’s for people who want to avoid taking long-term blood thinners, though they may need short-term medication after the procedure.
Birmingham, AlabamaAges 18 years+ - NCT04298723Recruiting
Left atrial appendage closure vs blood thinners after brain bleed
This trial compares a procedure that blocks a heart blood-choke point (the left atrial appendage) versus taking blood thinners by mouth. It is for people with atrial fibrillation who have had a brain bleed and may be safer avoiding long-term blood thinners.
Mannheim, Baden-WurttembergAges 18 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+ - NCT07620262Recruiting
Combined atrial fibrillation treatment and stroke prevention study
This study tests a new approach for people with atrial fibrillation (a type of irregular heartbeat) who are also at high risk for stroke. It combines a procedure to fix the heart's electrical signals with closing off a small pouch in the heart to reduce stroke risk, potentially avoiding long-term blood thinners.
Bay Shore, New YorkAges 18 years+ - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+ - NCT06358391Recruiting
Comparing two needles for left atrial access in heart procedures
This trial compares two devices used to create a small opening in the wall between the upper chambers of the heart so doctors can reach the left side to treat heart rhythm problems or other conditions. It may help if you need a left atrial procedure and are healthy enough for the puncture.
Bucheon-siAges 18 years+ - NCT06402851RecruitingPhase 4
Blood thinner or none for atrial fibrillation with dialysis
This trial compares two types of blood thinners (vitamin K antagonists and factor Xa inhibitors) versus no blood thinner in people with atrial fibrillation who are on dialysis or have very advanced kidney disease. It aims to see which option is safest and most effective for preventing strokes and bleeds.
Salvador, Estado de BahiaAges 18 years+ - NCT07353775Recruiting
Heart procedure using imaging and pulsed energy
This trial uses a special imaging tool inside the heart to guide a new type of energy (pulsed field) to treat a specific area in the heart that can cause atrial fibrillation (an irregular heartbeat). It may help people with paroxysmal or persistent atrial fibrillation who need a procedure called CTI ablation.
BeijingAges 18 years+ - NCT07390175Recruiting
New heart-ablation method for long-lasting arrhythmias
This study tests a new way to destroy the tissue causing dangerous heart rhythms using a detailed model of how the heart's electrical signals spread. It may be an option for people with long-lasting atrial fibrillation or hard-to-control ventricular arrhythmias who are already scheduled for a standard ablation procedure.
Madrid, MadridAges 18 years+ - NCT03243175RecruitingPhase 3
Avoiding blood thinners after brain bleeding in atrial fibrillation
This Phase 3 trial studies whether it’s safer to avoid long-term blood thinners after a spontaneous brain bleed in people with atrial fibrillation (an irregular heart rhythm). It compares different prevention strategies to lower the risk of stroke or other blood-vessel problems without causing new, serious bleeding.
LilleAges 18 years+ - NCT07621055Recruiting
AI software to guide heart rhythm ablation treatment
This study tests new AI software (Volta AF-Xplorer II) that helps doctors guide catheter ablation—a procedure to treat irregular heartbeats like atrial fibrillation. The software may help doctors perform the procedure more effectively and safely in real-world settings.
MarseilleAges 18 years+ - NCT06578104Recruiting
Pulsed AF Study: PulseSelect Catheter for Afib
This study tests a new way to treat atrial fibrillation (Afib) using a special catheter system called PulseSelect that delivers short bursts of energy to create scar tissue in the heart. It is for people whose Afib comes and goes or stays for a while but not more than a year, and who have not had a prior ablation procedure or have a pacemaker or defibrillator.
Tampa, FloridaAges 18 years+ - NCT07390214Recruiting
Comparing two catheters for repeat atrial fibrillation ablation
This study compares two types of catheters (AFFERA vs. standard contact-force guided) for a repeat ablation procedure in people whose atrial fibrillation or related symptoms returned after a first ablation. It aims to find which catheter works best for a second treatment.
Frankfurt am Main, HesseAges 18–85 - NCT05841056RecruitingPhase 3
Short amiodarone treatment to prevent new heart rhythm after surgery
This trial studies whether a short course of amiodarone started right after heart surgery can reduce problems from new-onset atrial fibrillation (a common fast heart rhythm) or flutter. It may help some patients avoid ongoing rhythm issues and improve recovery soon after discharge.
Hamilton, OntarioAges 18 years+ - NCT04804748Recruiting
DefiPace to help prevent heart rhythm problems after heart surgery
This study tests DefiPace in people who are having planned open-chest heart surgery (bypass and/or valve surgery) to see if it can help reduce certain post-surgery heart rhythm complications. Whether it’s usable depends on your planned procedure and specific health factors.
ViennaAges 18 years+ - NCT03830320RecruitingPhase 1
PET scan to look for blood clots in the heart or lungs
This Phase 1 study uses a PET scan to detect blood clots (thrombosis) in specific groups of people. It’s testing how well the scan can find clots and how it should be timed with other heart or illness tests.
Boston, MassachusettsAges 18–85 - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation, paroxysmal or persistent?
- Yes. Clin2 currently lists 469 recruiting atrial fibrillation, paroxysmal or persistent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation, paroxysmal or persistent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation, paroxysmal or persistent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.