Clinical trials
Atrial Fibrillation (Prevention of Stroke) clinical trials
Below are recruiting atrial fibrillation (prevention of stroke) clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07626411RecruitingPhase 3
Blood Thinner Study for Irregular Heartbeat
This study tests a new blood thinner to prevent strokes and blood clots in people with atrial fibrillation (a common heart rhythm problem). You may qualify if you have atrial fibrillation and at least one risk factor for stroke, or if you've never taken a blood thinner before.
Dothan, AlabamaAges 18 years+ - NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Rockford, IllinoisAges 18 years+ - NCT07349121Recruiting
Testing the Farapulse and Watchman devices together
This trial is for people who need both a special heart treatment called pulsed field ablation (FARAPULSE) and a device to close off a small pouch in the heart (WATCHMAN FLX Pro or WATCHMAN FLX) to prevent strokes. The study will see how well both procedures work when done together.
AalstAges 18 years+ - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT04700826RecruitingPhase 4
Preventing stroke, death, and memory decline in atrial fibrillation
This trial looks at ways to help people with atrial fibrillation lower their risk of stroke, premature death, and worsening memory. It may help by identifying which prevention approach works best for a broader community of patients.
Birmingham, West MidlandsAges 55–73 - NCT07523620Recruiting
Heart rhythm procedure with left atrial appendage closure
This trial tests a procedure that closes off a small pouch in the heart (left atrial appendage) while also treating irregular heartbeat (atrial fibrillation) with a catheter ablation procedure. The goal is to reduce your stroke risk and treat your symptoms without needing blood thinners long-term.
Brussels, B CAP RAges 18 years+ - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT05836987RecruitingPhase 3
Smartwatch monitoring trial to guide blood thinner use for AF
This study tests whether continuous heart-rhythm monitoring with a smartwatch can better guide treatment for atrial fibrillation (AF) while you stay on a blood thinner. The goal is to improve safety and reduce stroke risk by catching AF patterns more closely.
Phoenix, ArizonaAges 22–85 - NCT05900414Recruiting
Help choosing blood thinners to prevent stroke in AF
This trial tests a web-based decision aid that helps people with atrial fibrillation (AF) decide about stroke-prevention treatment, such as blood thinners. It may help you feel more confident and make safer choices by showing options at the right time after diagnosis.
Calgary, AlbertaAges 18 years+ - NCT06005233Recruiting
Smartwatch heart monitoring after unexplained stroke
This trial uses a smartwatch to look for hidden atrial fibrillation (an irregular heart rhythm) in people who have had a stroke or TIA with no known cause. It could help find the reason for the stroke and guide treatment to prevent another one.
MunichAges 40 years+ - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06187311RecruitingPhase 4
Rivaroxaban for atrial fibrillation patients
This trial tests two doses of rivaroxaban (15mg and 20mg) to see how well they prevent strokes in people with non-valvular atrial fibrillation, a type of irregular heartbeat not caused by a heart valve problem. It may be an option if you need blood thinners to lower your stroke risk.
SeoulAges 19–99 - NCT06324188Recruiting
Early ablation for afib to prevent stroke in high-risk patients
This trial tests whether an early procedure (catheter ablation) for atrial fibrillation (AF) can prevent strokes in people with a high risk of stroke. The goal is to see if this treatment is safer and more effective than standard care for patients with other health conditions.
Multiple LocationsAges 18 years+ - NCT06486792RecruitingPhase 4
Stroke prevention in patients with hidden atrial fibrillation
This trial tests if starting blood thinners can prevent another stroke in people who had a stroke but were found to have a hidden heart rhythm problem called atrial fibrillation. It is for older adults who have had a recent stroke without a known cause.
Paris, ParisAges 65 years+ - NCT07684053Recruiting
Digital screening for irregular heartbeat to prevent stroke
This study tests if using a digital device (like a smartwatch or phone) can help find an irregular heartbeat called atrial fibrillation. Finding it early may help prevent stroke, especially in people over 65.
Innsbruck, TyrolAges 65 years+ - NCT06949319Recruiting
Stroke Risk and Blood Clots in New Atrial Fibrillation
This study looks at stroke risk and blood clotting in people who have just been diagnosed with atrial fibrillation (AFib) that is not caused by a heart valve problem, and who have not yet taken blood thinners. It aims to better understand how blood clots form in this condition.
Esbjerg, Region SyddanmarkAges 18 years+ - NCT07407790Recruiting
Smartphone heart check after stroke
This study tests whether using a smartphone app to check your heart rhythm after a stroke can find hidden atrial fibrillation (an irregular heartbeat). If you had a recent stroke or TIA and are not already on blood thinners, you may be able to help doctors detect and prevent future strokes.
KristiansandAges 18 years+ - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+
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Common questions
- Are there clinical trials for atrial fibrillation (prevention of stroke)?
- Yes. Clin2 currently lists 44 recruiting atrial fibrillation (prevention of stroke) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation (prevention of stroke) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation (prevention of stroke) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Stroke Prevention in Patients With Atrial Fibrillation
- Stroke (in Patients With Atrial Fibrillation)
- ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION
- Persistent Atrial Fibrillation
- Paroxysmal Atrial Fibrillation
- Non Valvular Atrial Fibrillation
- Postoperative Atrial Fibrillation
- Atrial Fibrillation New Onset
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.