Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06592833RecruitingPhase 2
Psilocybin with or without pimavanserin for depression
This study tests whether combining psilocybin (a psychedelic substance) with pimavanserin (a medication that may help reduce side effects) works better than psilocybin alone for treating major depressive disorder. It may help people who have not responded well to other treatments.
New York, New YorkAges 21–80 - NCT06599099Recruiting
Deep brain stimulation for depression that hasn't responded to other treatments
This trial tests if deep brain stimulation (a surgical implant that sends gentle electrical pulses to a specific area of the brain) can help people with bipolar I disorder who are currently in a severe depressive episode and have not found relief from multiple treatments.
Boston, MassachusettsAges 22–64 - NCT06602518Recruiting
Airway changes after braces for deep overbite
This study looks at how fixing a deep overbite (where top teeth cover most of your bottom teeth) with braces may affect the size of your airway (the space in the back of your throat for breathing). It helps doctors understand if treatment can also help with breathing.
AlexandriaAges 12–16 - NCT06611592RecruitingPhase 2
Pramipexole for hard-to-treat OCD
This study tests if pramipexole can help people whose OCD hasn't improved with standard treatments like SSRIs or certain antipsychotics. You might qualify if standard therapies haven't worked for you.
BragaAges 18–64 - NCT06615102RecruitingPhase 3
Testing if angiotensin II prevents kidney injury after heart surgery
This trial tests whether giving a medicine called angiotensin II during heart surgery can help prevent acute kidney injury (a sudden drop in kidney function). It is for adults having certain types of heart surgery who have a higher risk of kidney problems.
BerlinAges 18 years+ - NCT06621394Recruiting
Mediterranean diet and mindful eating for depression and obesity
This study tests if a Mediterranean diet combined with mindful eating can help reduce depression severity in people who have both obesity and major depressive disorder. You would follow a special eating plan and learn mindfulness techniques to see if they improve your mood.
StuttgartAges 18 years+ - NCT06630065Recruiting
Ketamine study for depression using brain scans
This trial uses brain scans to understand how ketamine affects negative emotions in people with depression. It may help explain why ketamine works and who benefits most.
Paris, ParisAges 18 years+ - NCT06633016RecruitingPhase 2
ABX-002 for major depression (add-on treatment)
This trial tests a new medication called ABX-002 as an add-on to your current antidepressant. It's for people with moderate to severe depression who haven't gotten enough help from their current antidepressant alone.
Birmingham, AlabamaAges 18–65 - NCT06636227RecruitingPhase 1
Diclofenac dose study for alcohol use disorder
This study tests whether different doses of diclofenac, an anti-inflammatory drug, can help people reduce heavy drinking. It looks at how the drug affects drinking patterns and overall health.
Catonsville, MarylandAges 21–65 - NCT06644352Recruiting
Comparing right vs. left chest surgery for junction cancer
This study compares two surgical approaches (right side of the chest vs. left side of the chest) for removing a certain type of cancer at the gastroesophageal junction. It aims to find which approach leads to better outcomes.
BeijingAges 18–80 - NCT06645587Recruiting
Studying brain stimulation to reduce repetitive behaviors in autism
This trial tests if a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can help children with autism who have repetitive behaviors. It is for children aged 8 to 13 with an IQ of 70 or higher.
Rome, ItalyAges 8–13 - NCT06648642Recruiting
MRI-guided brain stimulation for alcohol use disorder
This study tests whether a new type of brain stimulation, guided by MRI and a robot, can help reduce heavy drinking in people with alcohol use disorder. The treatment is non-invasive and aims to improve brain function related to cravings.
San Antonio, TexasAges 18–65 - NCT06655610Recruiting
Nerve stimulation for ADHD in children and teens
This trial tests if a device that gently stimulates a nerve on the forehead can help children and teens with ADHD. You may be able to join if you are 7 to 17 years old and have an ADHD diagnosis.
Slagelse, Region SjællandAges 7–17 - NCT06660381RecruitingPhase 1
Psilocybin therapy for cannabis use disorder
This study tests if psilocybin (a substance that can change how you think and feel) can help people reduce or stop using cannabis. You will receive support and be monitored closely throughout the trial.
Baltimore, MarylandAges 18 years+ - NCT06667674Recruiting
Online therapy for prolonged grief in Sweden
This study tests an internet-based cognitive behavioral therapy program for people with prolonged grief disorder. It aims to help those who have lost a loved one at least six months ago and are still struggling with intense grief.
UppsalaAges 18 years+ - NCT06670079Recruiting
Prolonged exposure therapy for PTSD in pregnant patients
This trial tests if prolonged exposure therapy, a type of talk therapy for PTSD, is safe and helpful for pregnant people. If you have PTSD and are early in your pregnancy, this treatment may help you process trauma and feel better.
Burlington, VermontAges 18 years+ - NCT06675240Recruiting
Meditative neurofeedback for depression
This trial tests whether a technique that combines meditation with real-time brain activity feedback can help treat depression. It may help if you have moderate depression and are not currently struggling with substance abuse, psychosis, bipolar disorder, or suicidal behavior.
La Jolla, CaliforniaAges 18 years+ - NCT06677866Recruiting
Group therapy for teens with Fragile X or autism
This trial tests if group cognitive behavioral therapy (CBT) can help teens with Fragile X syndrome or autism spectrum disorder improve social and emotional skills. It looks at how teens with these conditions respond to a structured group program.
RomeAges 13–19 - NCT06683014RecruitingPhase 2
MDMA study for borderline personality disorder
This trial tests if a single dose of MDMA, given under supervision, can help people with borderline personality disorder (BPD). You will stay overnight after the session and be followed up for two weeks.
New Haven, ConnecticutAges 18–60 - NCT06685601Recruiting
Light therapy for kids with ADHD
This study tests if transcranial photobiomodulation (light therapy) can help children aged 6 to 18 with ADHD. It is for children who are not on other ADHD treatments.
Jinan, ShandongAges 6–18 - NCT06693726RecruitingPhase 4
Early blood pressure medication in the ER
This trial tests a drug called angiotensin II for people in the emergency room who need a specific dose of norepinephrine (a medicine to raise blood pressure) and are also getting antibiotics. The goal is to see if giving angiotensin II early can help stabilize blood pressure.
Iowa City, IowaAges 18–99 - NCT06698666RecruitingPhase 3
Can statins help treat depression?
This trial tests if adding a statin (a cholesterol-lowering medicine) to your current depression treatment improves symptoms. It is for adults aged 20 to 45 with mild to moderate depression who are not already taking a statin.
Cairo, Al AbbasiaAges 20–45 - NCT06372964RecruitingPhase 3
Lumateperone for pediatric bipolar depression
This study tests a new medication called lumateperone for treating depression in children and teens with bipolar disorder. It aims to see if this drug can help improve mood and daily functioning.
Dothan, AlabamaAges 10–17 - NCT07587112Recruiting
TMS treatment for OCD: brain imaging study
This study tests whether repetitive transcranial magnetic stimulation (rTMS) can help people with OCD. You will get rTMS while having brain scans (PET and MRI) to see how it affects your symptoms. It's a chance to learn more about your OCD and possibly find relief.
TaipeiAges 18–65
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,386 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.