Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,373 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06718140Enrolling by invitationPhase 1
Ultrasound for memory in mild cognitive decline
This study tests if a non-invasive ultrasound treatment can help memory in people with mild cognitive impairment (mNCD) and healthy older adults. It involves MRI scans and focused ultrasound sessions.
Charleston, South CarolinaAges 50–85 - NCT06688513Enrolling by invitation
Social needs app for cancer patients having surgery
This study tests a mobile app called Carealth that helps cancer patients address social needs like housing, food, or transportation. It is for patients who are having surgery with an overnight hospital stay and want to see if the app can improve their care.
Baltimore, MarylandAges 18 years+ - NCT06671691Enrolling by invitationPhase 1
Single-dose radiation for low-risk breast cancer
This trial tests a single, high-precision dose of radiation to the tumor instead of standard surgery or multiple radiation sessions. It is for women with a small, low-risk breast cancer who cannot or choose not to have surgery.
Palma, Balearic IslandsAges Any age - NCT06633263Enrolling by invitation
Combined therapy for depression and insomnia
This trial tests a combination of two behavioral therapies to improve both depression symptoms and sleep problems. It may help you if you have moderate depression and insomnia and can participate in French-language sessions.
LiègeAges 18–67 - NCT06485349Enrolling by invitation
Olive leaf extract for anxiety and weight in women
This study tests whether an olive leaf extract can help with mild anxiety and weight management in women who are overweight or have moderate obesity. Participants take the extract or a placebo daily for a period, and their anxiety levels, inflammation, and weight are tracked.
Guadalajara, JaliscoAges 18–40 - NCT06412432Enrolling by invitation
Exercise and rehab for heart amyloidosis
This study tests whether a supervised exercise and rehabilitation program can help people with a specific type of heart amyloidosis (ATTRwt) feel better and improve their heart function. It may be a good fit if you have stable heart failure and can safely exercise.
NaplesAges 18 years+ - NCT06389175Enrolling by invitation
Non-invasive ear stimulation for depression
This study uses a gentle, non-invasive device that stimulates the vagus nerve in your ear to see if it can improve how your stomach and brain communicate, which may help with depression symptoms.
BonnAges 18–55 - NCT06306157Enrolling by invitationPhase 4
Low dose naltrexone for complex regional pain syndrome
This trial tests whether a low dose of naltrexone, a medication that may help calm overactive immune and pain signals, can reduce pain and improve daily life in people with complex regional pain syndrome (CRPS), a chronic condition that often causes severe pain and swelling.
New York, New YorkAges 18–85 - NCT06215547Enrolling by invitation
Nerve stimulator for nausea and vomiting
This trial tests a device that sends mild electrical pulses to the stomach to help control severe nausea and vomiting caused by gastroparesis (stomach that empties slowly). It is for people aged 18–70 whose symptoms have not improved with medication.
Richardson, TexasAges 18–70 - NCT06215313Enrolling by invitation
Comparing two therapies for trauma memories
This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.
Eindhoven, North BrabantAges 18–70 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06002100Enrolling by invitation
Predicting depression treatment response with brain imaging
This study uses a special headband (TD-fNIRS) that measures brain activity to see if it can predict how well different depression treatments work. You would be starting a new treatment for depression (like ketamine, SPRAVATO, TMS, or antidepressants) and wear the headband before and during treatment.
Costa Mesa, CaliforniaAges 18–75 - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Birmingham, AlabamaAges 18 years+ - NCT05601596Enrolling by invitation
Study of menstrual samples for endometriosis
This study collects menstrual blood and cheek-swab DNA to better understand endometriosis. It may help researchers find markers that could eventually lead to earlier diagnosis and improved treatment planning.
Manhasset, New YorkAges 18–40 - NCT05600868Enrolling by invitation
Testing dual attention during EMDR therapy for PTSD
This study tests whether adding “dual attention” to EMDR therapy helps people with high PTSD symptoms. If you have significant PTSD symptoms, this approach may improve how well the therapy works, but it depends on safety and recent treatment history.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05576116Enrolling by invitation
Bariatric surgery plus pancreas transplant after kidney transplant
This trial studies whether adding bariatric (weight-loss) surgery and a pancreas transplant can improve health in people with long-term type 2 diabetes who already received a kidney transplant. It may help with blood sugar control and related metabolic health, while also needing careful safety screening for kidney function and blood vessel health.
Toronto, OntarioAges 18–50 - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT05301361Enrolling by invitationPhase 1
Test of brain testing during stimulant treatment for ADHD
This trial checks whether a “NIH Toolbox” set of child-friendly tests can detect changes when stimulant medicine is used for ADHD. It may help doctors better measure how well stimulant treatment is working in people with intellectual disability.
Sacramento, CaliforniaAges 6–24 - NCT05165316Enrolling by invitation
Long-acting antipsychotic options for schizophrenia
This study looks at long-acting (extended-release) antipsychotic medicine options in people with schizophrenia, compared with regular tablets. You may be able to join if you were already part of a related earlier study or its real-world follow-up.
Ramat GanAges 18 years+ - NCT04762459Enrolling by invitationPhase 3
Almonertinib after lung tumor surgery, with or without chemo
This study tests whether almonertinib taken after complete surgery can improve outcomes for people with stage II–IIIA non-small cell lung cancer (NSCLC) that has certain EGFR gene changes. It also compares almonertinib plus chemotherapy versus almonertinib alone to see which approach is safer and works better.
Beijing, Beijing MunicipalityAges 18–130 - NCT04043442Enrolling by invitationPhase 2
Brain stimulation study for alcohol use with mild brain injury
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
Hines, IllinoisAges 22–65
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,373 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.