Clinical trials
Bipolar clinical trials
Below are recruiting bipolar clinical trials, each written for real people, not researchers. We’re tracking 241 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05025605RecruitingPhase 1
Study medicine for agitation in youth with bipolar or schizophrenia
This Phase 1 trial tests whether BXCL501 is safe and can help reduce agitation in children and teens who have bipolar disorder or schizophrenia. You may be considered if your agitation is significant during screening, but certain recent medication and health factors can make you ineligible.
Anaheim, CaliforniaAges 10–17 - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT06197048Recruiting
Nutrition counseling for schizophrenia or bipolar disorder
This study tests whether nutritional counseling can improve body measurements and health markers in people with schizophrenia, psychosis, or bipolar disorder. It may help you manage weight and overall health.
Drammen, AkershusAges 18 years+ - NCT07858565Recruiting
Quality of life with quetiapine for schizophrenia or bipolar disorder
This study looks at how well patients feel and how safe it is when taking quetiapine alone or with other medicines for schizophrenia or bipolar disorder. It aims to help doctors understand the best ways to use this treatment.
SarajevoAges 18–65 - NCT06384755Recruiting
Honest Open Proud for psychosis and bipolar disorder
This study tests a program called Honest, Open, Proud to help people with psychosis or bipolar disorder deal with stigma and decide whether to share their diagnosis. It aims to reduce shame and improve confidence.
OsloAges 18–65 - NCT06426810Recruiting
New vs. standard surgical tool for bleeding control after lymph node biopsy
This trial compares two tools used during surgery to stop bleeding after a sentinel lymph node biopsy for breast cancer. It aims to see if a newer bipolar system is better than the standard electrocautery device.
Seoul, Dongjak-guAges 20–80 - NCT07733167RecruitingPhase 3
Epinephrine injection during prostate surgery for large prostates
This study tests whether injecting a drug called epinephrine into the prostate during surgery can improve outcomes for men with large prostates. It aims to reduce bleeding and make the surgery safer and more effective.
Banhā, Qalyubia GovernorateAges 40 years+ - NCT07699445RecruitingPhase 4
Lumateperone for weight and mood in bipolar depression
This study tests if lumateperone, a medication for bipolar depression, can also help with weight and aging in people with obesity. You may qualify if you have bipolar I depression and a body mass index (BMI) over 30.
Boston, MassachusettsAges 18–65 - NCT07679204Recruiting
Personality and life satisfaction in bipolar and depression
This study looks at how personality traits and life satisfaction affect people with bipolar II disorder or major depression. You will fill out questionnaires about your feelings and daily life.
ElâzığAges 18 years+ - NCT07648888Recruiting
Water Vapor Therapy Versus Bipolar Surgery for Enlarged Prostate
This trial compares two minimally invasive surgical treatments for benign prostatic hyperplasia (an enlarged prostate that causes urinary problems). Both approaches aim to relieve urinary symptoms while preserving your ability to ejaculate normally.
Banī Suwayf, Beni Suweif GovernorateAges 50 years+ - NCT07627178Recruiting
Comparing laser treatments for enlarged prostate
This study compares three different surgical laser techniques to treat benign prostate enlargement (BPH) that causes severe urinary symptoms and hasn't improved with medication. The goal is to find which method is safest and works best for large prostates.
Tanta, Gharbia GovernorateAges Any age - NCT06706687Recruiting
Brain imaging and epigenetics in frontotemporal dementia and bipolar disorder
This study uses brain scans and genetic tests to understand the differences between behavioral variant frontotemporal dementia (bvFTD) and bipolar disorder. It may help improve diagnosis and find better treatments for both conditions.
Milan, MIAges 18 years+ - NCT07589647Recruiting
Brain Stimulation for Bipolar Disorder and Weight Management
This study tests whether a small electrical stimulation device targeting a specific brain region (the suprachiasmatic nucleus) can help improve metabolic health and weight in people with stable bipolar disorder who also have obesity. The goal is to see if this approach is safe and effective.
Hangzhou, ZhejiangAges 18–45 - NCT07573839Recruiting
Predicting bipolar disorder relapse using voice and video analysis
This study uses artificial intelligence to analyze speech patterns and facial expressions from people with bipolar disorder to predict who might have a relapse. If successful, it could help doctors identify warning signs earlier and prevent episodes before they happen.
ShanghaiAges 18–64 - NCT06134349Recruiting
Bipolar Lithium Imaging Scan Study
This study uses MRI scans to look at how lithium affects the brain in people with bipolar disorder. It may help researchers understand why lithium works and how to use it better.
Leiden, South HollandAges 18 years+ - NCT07562386Recruiting
Prostate Surgery Outcomes and Patient Satisfaction Study
This study compares two surgical techniques for enlarged prostate (benign prostatic hyperplasia, or BPH) to see which one works better and how satisfied patients are afterward. If you have moderate prostate enlargement and urinary symptoms, this trial might help improve your treatment.
HamarAges Up to 80 years - NCT07556692Recruiting
Home Brain Stimulation for Bipolar Depression
This study tests whether a device you use at home can help reduce depression symptoms in people with bipolar disorder. The device uses gentle electrical stimulation on the scalp to potentially improve mood.
LondonAges 18 years+ - NCT07540338RecruitingPhase 1/Phase 2
New Lithium Capsule Study for Bipolar I
This study compares a new lithium capsule (AL001) to a standard lithium capsule in people with Bipolar I Disorder. It aims to see how well your body absorbs each capsule and whether AL001 is safer or more tolerable.
Boston, MassachusettsAges 18–65 - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT07472075RecruitingPhase 2
Melatonin vs placebo for bipolar disorder
This trial tests whether taking melatonin (a natural sleep hormone) helps stabilize mood in people with bipolar disorder compared to a placebo (a pill with no active ingredient). It may help improve sleep and mood stability.
FrederiksbergAges 18–70 - NCT07437833Recruiting
Self-regulation exercises for women with ADHD and stable bipolar disorder
This study tests how six different self-regulation techniques affect your body and brain during one session. It's designed for women with both ADHD and stabilized bipolar disorder who have been off psychiatric medications for at least two years.
PoznanAges 18–35 - NCT07412132RecruitingPhase 3
Testing lacosamide for hard-to-treat bipolar depression
This study tests if a medication called lacosamide can help people with bipolar depression that has not improved with at least two other treatments. It's for those with moderate to severe depression in bipolar I or II.
São Paulo, São PauloAges 18–65 - NCT05977023RecruitingPhase 2
NMDA-targeted medicine to treat bipolar I depression
This Phase 2 study tests a medication that works on NMDA receptors to improve depression symptoms in people with bipolar I disorder. It may help if you’re currently in a bipolar depression episode and other mood treatments haven’t fully controlled it.
TaichungAges 18–65 - NCT07306468Recruiting
Exercise and lung health in schizophrenia and bipolar disorder
This study looks at how schizophrenia or bipolar disorder affects your ability to exercise, your lung function, and overall quality of life. It compares people with these conditions to healthy volunteers.
Çankırı, ÇankırıAges 18–65
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Common questions
- Are there clinical trials for bipolar?
- Yes. Clin2 currently lists 241 recruiting bipolar studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.