Clinical trials
Bone Defects clinical trials
Below are recruiting bone defects clinical trials, each written for real people, not researchers. We’re tracking 41 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03997578Recruiting
Gum surgery for deep periodontal bone defects
This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.
MurciaAges 18 years+ - NCT06270303Recruiting
Bone substitute for gum disease between tooth roots
This trial tests a bone substitute material to help repair gum defects between the roots of back teeth (molars) that have not healed with standard deep cleaning. If you have a single area of gum bone loss between the roots, this surgery might help regenerate the bone.
GothenburgAges 18 years+ - NCT01889381RecruitingPhase 2
Transplanting facial and jaw bone using donor tissue
This trial studies a special surgery to replace part of the skull, face, and jaw using donor tissue. It also tests medicines to help your body accept the transplant, aiming to restore function and appearance after serious injury.
Baltimore, MarylandAges 18–65 - NCT06676826Recruiting
Comparing two gum-graft materials for bone defects
This study tests two types of gum-graft materials to see which works better for rebuilding bone next to deep pockets caused by gum disease. Both materials are used during a minor surgical procedure to help your gums and bone heal stronger.
BernAges 18 years+ - NCT06919081RecruitingPhase 2
Stem cell eye drops for chronic cornea problems
This study tests whether a special substance from stem cells (called secretome) can help heal chronic surface problems on the eye that haven't gotten better with standard treatments. It's for people with a stubborn scratch or defect on the cornea that has lasted more than 14 days.
Chicago, IllinoisAges 18 years+ - NCT07671963Recruiting
Bone Graft Options for Gum Disease Surgery
This trial tests two bone-replacement materials (a synthetic bone substitute and a natural bone graft) placed during gum surgery to see which one better helps rebuild bone and gum support around teeth with deep pockets.
Cagliari, ItalyAges 18–80 - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT06915233RecruitingPhase 3
MACI for ankle cartilage defects in adults
This trial tests a treatment called MACI for people with damaged cartilage in their ankle. It uses your own cells to grow new cartilage, which may help reduce pain and improve how you can use your ankle.
Sacramento, CaliforniaAges 17–65 - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+ - NCT06893302Recruiting
Bone marrow injection during knee scope for cartilage or meniscus
This trial tests if adding a bone marrow injection to standard knee arthroscopy helps your knee heal better. It is for people with a torn meniscus or damaged cartilage who have healthy knee joints without arthritis.
New York, New YorkAges 18–64 - NCT06991998Enrolling by invitation
Comparing tooth graft vs. bone graft for gum disease bone defects
This trial tests whether a graft made from your own extracted tooth works as well as a traditional bone graft, both combined with a special enamel protein, to repair bone loss from gum disease.
Budapest, BudapestAges 18 years+ - NCT07522684Recruiting
Gel treatment for deep gum bone loss around teeth
This trial tests a special gel made with growth-promoting compounds and animal-derived material to help repair deep bone loss in the gums around teeth. It may help restore bone that periodontitis (advanced gum disease) has damaged.
Ribeirão Preto, São PauloAges 18 years+ - NCT06633640Enrolling by invitationEarly Phase 1
Algae bone graft for gum disease bone defects
This study tests a new bone graft material made from algae, used with a collagen membrane, to help repair bone damage caused by gum disease. It might be an option if you have a deep pocket in the bone around a tooth and are healthy enough for the procedure.
CairoAges 20–65 - NCT06347263Recruiting
Gum surgery technique for deep pockets between teeth
This trial tests a surgical technique to treat deep gum pockets between teeth. It compares using a special gum-saving method alone, with a bone graft, or with a platelet-rich fibrin injection to see which helps heal the bone best.
CairoAges 18–50 - NCT07424716Recruiting
Bone healing with platelet-rich fibrin after cyst removal
This trial tests whether a natural blood concentrate (PRF) helps jawbone heal better after removing a dental cyst. It may improve recovery and reduce the need for additional bone grafting.
Sanaa, Sanaa GovernorateAges 18–80 - NCT06653868Recruiting
Sticky bone grafts for front tooth implants
This trial tests two different types of sticky bone graft materials placed around a dental implant right after a tooth is removed. It aims to see which type helps the bone heal better around the implant in the front of your mouth.
CairoAges 20–50 - NCT01852370Enrolling by invitationPhase 1/Phase 2
Lung and bone marrow transplant plan for immune system disorders
This early-phase study tests a step-by-step transplant approach: first replacing the lungs, then doing a bone marrow (stem cell) transplant to treat certain immune deficiency diseases. It may help people whose immune problem has led to severe, end-stage lung disease.
Pittsburgh, PennsylvaniaAges 5–45
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Common questions
- Are there clinical trials for bone defects?
- Yes. Clin2 currently lists 41 recruiting bone defects studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone defects trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone defects trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.