Clinical trials
Bone Defects clinical trials
Below are recruiting bone defects clinical trials, each written for real people, not researchers. We’re tracking 42 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06156904Recruiting
Study of b.Bone bone graft for defects in arms, legs, pelvis
This trial is following patients who receive a bone graft using a product called b.Bone to treat bone defects in the arms, legs, or pelvis. Researchers will collect information during your regular follow-up visits to see how well the bone heals.
BerlinAges 18 years+ - NCT06736457Recruiting
Safety and performance of AdvanCore bone void filler
This study tests a new bone filler called AdvanCore for people with a single bone fracture or defect that needs a graft. It aims to see if the filler is safe and works well to help the bone heal.
Guimarães, Braga DistrictAges 18 years+ - NCT07066228Recruiting
Rebuilding bone using a patient's own stem cells
This trial tests whether using a patient's own bone marrow stem cells can help repair large gaps in the shin or arm bones that haven't healed on their own. The stem cells are grown in a lab to create new bone tissue, which may avoid the need for metal implants or donated bone.
Xinxiang, HenanAges 18–55 - NCT04112992Recruiting
Registry for post-injury long bone bone defects
This study is a registry that collects real-world information about adults with bone gaps in the long bones caused by injury. It may help researchers understand what treatments work best and improve care for these defects over time.
Los Angeles, CaliforniaAges 18 years+ - NCT07254494Recruiting
Bone Regrowth Guide for Lower Jaw Implants
This study tests two types of membranes used to grow bone in the lower jaw before placing dental implants. Participation lasts about one year and involves a bone-regrowth procedure to prepare for implants.
BeirutAges 18–80 - NCT04449211RecruitingEarly Phase 1
3D-printed implant for large bone defects
This trial studies whether a custom 3D-printed implant helps heal a large bone defect after injury or tumor removal. If you have a bone gap bigger than 5 centimeters and can safely have surgery, this may be a treatment option being tested.
Ho Chi Minh CityAges 18 years+ - NCT07209033Recruiting
Testing FlexiOss for bone repair in leg and foot fractures
This trial tests a new material called FlexiOss to help heal broken bones in the leg or foot. It aims to see if the material is safe and effective for bone regeneration.
KrakowAges 18–75 - NCT06269354Recruiting
3D-printed implant for large lower-limb bone defects
This trial is testing a new way to treat large bone defects in the lower leg or thigh using a custom 3D-printed titanium implant. It may help people whose bone didn't heal after injury, infection, or tumor removal.
Beijing, HaidianAges 18–90 - NCT05668182Recruiting
TRUMATCH graft cage for broken thigh/leg/arm bone gaps
This study looks at how well a specific metal implant (the TRUMATCH graft cage) works when there is a missing segment of a long bone in the arm, thigh, or shin. It may help stabilize the bone while doctors rebuild the defect with standard surgical care.
San Diego, CaliforniaAges 18 years+ - NCT06249906Recruiting
Bioceramic material for bone defect repair
This trial tests a new bioceramic material to repair bone defects. It is for adults aged 18 to 65 who are generally healthy and can follow the study plan.
Nanjing, JiangsuAges 18–65 - NCT07546279Recruiting
Bone substitutes with gum graft for deep gum pockets
This trial tests two different bone-filling materials combined with a gum graft to repair deep pockets in your gums caused by gum disease. The goal is to help your gums heal and regain support around your teeth.
MilanAges Any age - NCT06374342Recruiting
Bone substitutes study after surgery follow-up
This study follows patients who receive a Teknimed bone substitute during surgery for bone defects. It collects data on how well these bone fillers work in real-world use.
Mainvilliers, Eure et LoirAges 18 years+ - NCT03608280Recruiting
3D-printed implant vs own bone for rebuilding eye socket
This study compares two ways to rebuild part of the eye socket bone: a 3D-printed implant versus using the patient’s own bone. It may help show which approach works better to restore eye position and symptoms like double vision after an injury or surgery.
Pierre-BéniteAges 18–90 - NCT06975306Recruiting
Bone Graft for Kneecap Defect in ACL Surgery
This study looks at how a bone graft used to fill a gap in the kneecap affects healing and recovery after ACL reconstruction. Researchers want to see if the graft helps the bone heal better and improves your knee function.
Phoenix, ArizonaAges 18–40 - NCT06003101RecruitingPhase 3
Blood treatments for hip labrum tear surgery
This study tests whether adding platelet-rich plasma (a blood concentrate), platelet-poor plasma, or bone marrow concentrate during hip surgery helps people with a torn labrum recover better. If you need hip arthroscopy and haven't had prior hip surgery, you may be able to join.
Boston, MassachusettsAges 18 years+ - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65 - NCT06349629Recruiting
Testing a new dissolving metal implant for joint fractures
This trial tests a new 3D-printed metal implant made of a special magnesium alloy that dissolves over time. It is designed to help mend broken bones near joints, such as wrist, shoulder, or knee fractures, where there is a missing piece of bone.
Beijing, HaidianAges 18–80 - NCT06048042RecruitingPhase 4
Comparing tooth graft vs bone graft for gum disease bone loss
This trial tests if using a tooth that is removed (like a wisdom tooth) to fill deep gum pockets works as well as using a piece of your own bone. It may help rebuild the bone around a damaged tooth.
CairoAges 18–50 - NCT07779278Enrolling by invitation
Custom implants for complex limb bone reconstruction
This trial tests custom-made metal implants to fix severe bone problems in the arms or legs, such as crooked bones, shortened bones, or missing pieces. The implant is designed just for you using a 3D computer model, and the goal is to help your bones heal in a better shape and work properly.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07254117Recruiting
Study on gum tissue healing for severe gum disease
This trial tests whether special granulation tissue can help regenerate bone and gum support in people with severe gum disease who still have deep bone pockets after initial treatment. It may offer a better way to heal these defects.
RigaAges Any age - NCT07389681Recruiting
Bone loss repair: Masquelet technique vs transport nails
This study compares two surgical techniques for rebuilding bone in the lower leg or thigh after significant bone loss. If you need this type of surgery, you may be able to join and help doctors learn which method works best.
BordeauxAges 18 years+ - NCT06973239Recruiting
Safety and performance of a new bone filler injection
This trial tests Neocement® Inject P, a paste that hardens to fill bone gaps. It might help if you have a bone defect from surgery or injury that does not need structural support.
BarcelosAges 18 years+ - NCT06973226Recruiting
Testing the safety of Neocement bone cement
This trial tests a new bone cement (Neocement®) for treating bone defects caused by surgery or injury. It aims to see if the cement is safe and works well to fill the gap.
BarcelosAges 18 years+ - NCT03909139Recruiting
Stem-cell injection during hip arthroscopy for labral tears
This trial looks at whether using BMAC (a substance made from a person’s own bone marrow) during hip arthroscopy helps people with labral tears caused by hip impingement. It aims to improve hip pain and function by combining the injection with the standard surgical repair.
Boston, MassachusettsAges 18 years+
Hear when a new Bone Defects trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for bone defects?
- Yes. Clin2 currently lists 42 recruiting bone defects studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone defects trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone defects trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.