Clinical trials
Bone Diseases, Metabolic clinical trials
Below are recruiting bone diseases, metabolic clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07010432RecruitingPhase 1
Trial of Cagrilintide for bone health in postmenopausal women
This trial tests whether cagrilintide, a medicine similar to a natural hormone called amylin, can affect bone health. It is for postmenopausal women with obesity who do not have bone disease or other conditions affecting bone metabolism.
HerlevAges 50–70 - NCT06041789RecruitingPhase 2
Does a memory medication affect bone health?
This study looks at whether a common memory medication (called donepezil) can also help keep your bones strong. If you have memory problems and are willing to start this medication, you might be able to join.
Durham, North CarolinaAges 50 years+ - NCT02356653RecruitingEarly Phase 1
Stem cell transplant help for children lacking a matching sibling
This expanded-access study offers a specific type of stem cell transplant preparation that removes certain immune cells (CD3 and CD19) from donor stem cells. It is for children who need a transplant but do not have a fully matched sibling donor and whose team cannot use the hospital’s usual matching device protocol.
Philadelphia, PennsylvaniaAges Up to 30 years - NCT07368946Recruiting
Phosphate study for people with kidney disease
This study looks at how the body handles phosphate in people with chronic kidney disease. It may help researchers understand how to better manage phosphate levels to improve health.
Dallas, TexasAges 18 years+ - NCT06949280Recruiting
Peanuts, weight loss, and bone health study
This study tests whether eating peanuts daily during weight loss affects bone health in adults aged 50 to 75.
New Brunswick, New JerseyAges 50–75 - NCT03784651Recruiting
How breast cancer treatment changes metabolism and bone
This study looks at how standard breast cancer treatments affect your body’s metabolism and bones in postmenopausal people with early-stage breast cancer. It may help doctors better predict and prevent bone and metabolic side effects from treatment.
Copenhagen, DanmarkAges 50–70 - NCT07731438Recruiting
Calorie restriction and bone marrow fat in obesity and diabetes
This study tests whether a calorie-restricted diet can change the fat in your bone marrow and how it relates to bone health and energy use. It is for premenopausal women and men who are either obese or lean and do not have diabetes.
PragueAges 21–55 - NCT07059065Recruiting
New bone graft for spinal fusion surgery
This trial tests a new bone graft material called FIBERGRAFT Aeridyan for people needing spinal fusion to stabilize their lower back. It aims to see if it helps bones heal together safely and effectively.
Sacramento, CaliforniaAges 18 years+ - NCT07609277Recruiting
Blood test to track giant cell bone tumors
This study uses a simple blood test (TRACP-5b) to help diagnose and monitor giant cell tumors of the bone. Researchers want to see if this test can better track how the tumor responds to treatment or comes back over time.
BrnoAges 18 years+ - NCT07666126Recruiting
Uric acid and gum bone health study
This study looks at whether high uric acid levels affect the bone around your teeth. If you are between 18 and 65, have at least 20 natural teeth, and are either healthy or have high uric acid and gum disease, this trial may be for you.
RizeAges 18–65 - NCT05823376Recruiting
Avatrombopag to help platelets recover after bone marrow transplant
This trial studies whether avatrombopag can help your platelet count recover after a bone marrow transplant from an unrelated donor (UCBT) in certain bone marrow failure diseases. If platelets recover better, it may reduce risks related to low platelets after transplant.
Hefei, AnhuiAges 12 years+ - NCT04644016RecruitingPhase 2
Cord blood transplant for children and young adults with blood cancers
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
New York, New YorkAges Up to 21 years - NCT04049539RecruitingPhase 1/Phase 2
Vyxeos for AML that stays after initial chemotherapy
This trial tests whether Vyxeos (a type of chemotherapy) can treat acute myeloid leukemia (AML) that did not fully go away after standard induction (“7+3”) chemotherapy. It targets people whose leukemia is still present in the bone marrow and need a stronger “re-induction” treatment.
Sacramento, CaliforniaAges 18–75 - NCT05880914Recruiting
Personalized treatment study for bone disease in kidney failure
This trial looks at a personalized approach to diagnosing and treating bone problems caused by long-term kidney disease. It may help by matching treatment plans to the type of bone turnover found in your tests or biopsy.
St Louis, MissouriAges 18 years+ - NCT06226168Recruiting
Hypoxia exercise for bone health in premenopausal women
This study looks at how an exercise program done in low-oxygen (hypoxia) conditions affects bone health and metabolism in premenopausal women. It could help if you're interested in improving your bone density naturally.
KrakowAges 50–59 - NCT05971329Recruiting
Pilot study of bone graft for cervical disc wear and nerve symptoms
This trial tests a new bone graft product (ZetaFuse™) used during front-of-the-neck surgery to treat “wear and tear” in the cervical (neck) discs causing nerve problems. It may help relieve pain and nerve-related symptoms when other treatments haven’t worked.
Randwick, New South WalesAges 22–75 - NCT01962415RecruitingPhase 2
Reduced-intensity stem cell transplant for non-cancer disorders
This trial tests whether a gentler (reduced-intensity) conditioning treatment before a stem cell transplant works for non-cancer diseases. It uses specific donor stem cell matches and checks heart, lung, liver, and kidney function to help lower transplant stress while still aiming for benefit.
Pittsburgh, PennsylvaniaAges 2 months–55 years - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT06839456RecruitingPhase 1/Phase 2
Stem cell addback to prevent infections after transplant
This trial tests whether adding back certain immune cells after a stem cell transplant can help prevent serious viral or fungal infections. It's for children and young adults up to age 25 who need a transplant for a blood cancer or other curable disease.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT05623150Recruiting
Biopsy-based study for alcohol and metabolic liver disease
This trial studies people with liver disease linked to alcohol use or metabolic syndrome (a cluster of conditions like weight gain and insulin resistance). It uses recent standard-of-care liver biopsy results to better understand these chronic liver problems and how they relate to cancer risk.
NiceAges 18 years+ - NCT04508088Recruiting
Study of bones and bone marrow in new Crohn’s
This study looks at how Crohn’s disease affects bones and bone marrow soon after diagnosis. It may help researchers understand disease effects and improve future care, either by comparing you to healthy controls or by tracking changes over time.
Boston, MassachusettsAges 13–20 - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Irvine, CaliforniaAges 18 years+ - NCT06978296Recruiting
HIMARS: Stereotactic radiation for prostate cancer spread
This trial tests adding targeted radiation (SRT) to bone or lymph node metastases in men with prostate cancer that has continued to grow despite hormone therapy, chemo, or other treatments. The goal is to see if radiation can help control the disease and improve outcomes.
Saint-HerblainAges 18 years+ - NCT05932017Enrolling by invitation
Compare two ways to see during gum surgery
This trial compares two tools surgeons use to see during gum (periodontal) surgery: magnifying loupes versus a videoscope. It may help improve how the procedure is done for people with more severe gum disease.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for bone diseases, metabolic?
- Yes. Clin2 currently lists 53 recruiting bone diseases, metabolic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone diseases, metabolic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone diseases, metabolic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.