Clinical trials
Brachytherapy clinical trials
Below are recruiting brachytherapy clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07141732RecruitingPhase 1
Brain radiation therapy during surgery for new glioblastoma
This trial tests giving a precise dose of radiation directly to the tumor area during surgery for newly diagnosed glioblastoma. The goal is to destroy remaining tumor cells immediately after removal, which may improve outcomes.
Moscow, MoscowAges 40–75 - NCT03422198RecruitingPhase 3
Short course vaginal radiation after hysterectomy
This trial tests a short course of targeted vaginal radiation (brachytherapy) after surgery for certain early endometrial cancer. It may help prevent the cancer from coming back in the vaginal area after the uterus has been removed.
Palo Alto, CaliforniaAges Any age - NCT05242861Recruiting
Reviewing outcomes after brachytherapy for women’s cancers
This study looks back at medical records to understand results after brachytherapy (a form of cancer radiation delivered from inside or close to the tumor) in women with gynecologic cancer. It may help doctors improve future treatment decisions, but you would not have to receive an experimental treatment.
Hangzhou, ZhejiangAges 18–80 - NCT06982469Recruiting
High-dose radiation for prostate cancer return after surgery
This trial tests a high-dose radiation treatment (brachytherapy) that places tiny radioactive seeds directly into the area where your prostate was. It is for men whose prostate cancer has returned only in that area after having their prostate removed.
Pamplona, Foral Community of NavarreAges 18–80 - NCT07426055RecruitingPhase 2/Phase 3
Prostate cancer radiation boost comparison study
This trial compares two types of radiation treatments for prostate cancer that has not spread to lymph nodes or other parts of the body. It tests whether adding a higher dose of radiation to the main tumor helps control the cancer better than standard radiation alone.
Zamość, Lublin VoivodeshipAges 18 years+ - NCT05640999RecruitingPhase 2
Trial for early uterine cancer with POLE mutation after surgery
This Phase 2 trial studies an added (adjuvant) treatment for early-stage uterine cancer that has a specific genetic change called POLE mutation and does not have a p53 abnormal pattern. The goal is to lower the risk of the cancer coming back after surgery.
Anchorage, AlaskaAges 18 years+ - NCT06240559Recruiting
Brachytherapy treatment verification study
This study checks if doctors can better verify brachytherapy (a type of internal radiation) during treatment for gynecological or prostate cancer. It may help improve accuracy and outcomes for patients receiving this therapy.
Maastricht, LimburgAges Any age - NCT06402864RecruitingPhase 3
Internal radiation for rectal preservation in intermediate rectal cancer
This study is testing whether a special internal radiation treatment (contact X-ray brachytherapy) can help people with intermediate-stage rectal cancer avoid surgery and keep their rectum intact. It is for patients who are also receiving mFolfirinox chemotherapy.
Avignon, FranceAges 18–99 - NCT04705467Recruiting
3D scanning of needles during gynecologic radiation treatment
This study uses 3D imaging to help guide needle-based radiation treatment for certain gynecologic cancers. If you are already scheduled to receive this type of brachytherapy, the trial may help make the treatment planning more accurate.
London, OntarioAges 18 years+ - NCT04610372Recruiting
Targeted radiation plus hormone therapy for prostate cancer spread
This study compares different ways of giving radiation (SABR or brachytherapy) along with long-term hormone therapy for men whose prostate cancer has spread to a limited number of spots in the body. It aims to see which radiation approach controls the cancer as well as possible while keeping quality of life in mind.
Kelowna, British ColumbiaAges 18 years+ - NCT06543576RecruitingPhase 1/Phase 2
Radiation and drug therapy for stage IVB cervical cancer
This trial tests combining external and internal radiation with chemotherapy and immunotherapy for stage IVB cervical cancer that has not been treated before. The goal is to see if this approach can help shrink tumors and improve outcomes.
Los Angeles, CaliforniaAges 18 years+ - NCT06531551Enrolling by invitation
Acupressure for patients receiving brachytherapy
This study tests whether acupressure (gentle finger pressure on specific body points) can help patients who are receiving brachytherapy for gynecological cancer. It may help manage side effects and improve comfort.
Selçuklu, KonyaAges 18–65 - NCT02993900Recruiting
Brachytherapy guided by imaging for gynecologic cancers
This study tests image-guided internal radiation (brachytherapy) for certain gynecologic cancers. It may help deliver radiation more precisely by using scans done close to enrollment.
Baltimore, MarylandAges 18–100 - NCT03238378Recruiting
Radiation boost plus warming for recurrent head and neck tumors
This trial tests a “salvage” treatment that combines targeted radiation (brachytherapy) with controlled body warming (hyperthermia) for head and neck cancer that has come back. It may help by better shrinking tumors while fitting the treatment to the tumor’s exact location.
ErlangenAges 18 years+ - NCT03249519Recruiting
Radiation plus heat for advanced cervical cancer
This trial studies whether adding controlled heat (“hyperthermia”) to radiation therapy (or radiation with chemotherapy) can improve outcomes in advanced cervical cancer. It focuses on people who can safely receive intensive pelvic radiation and heat treatment.
ErlangenAges 18 years+ - NCT03424850RecruitingPhase 1/Phase 2
Tested different radiation doses for early prostate cancer
This trial studies how safe and effective different high-dose radiation levels are for prostate cancer placed directly in the prostate (HDR brachytherapy). It may help by finding a dose that controls the cancer while keeping side effects acceptable.
St Louis, MissouriAges 18 years+ - NCT03785288RecruitingPhase 3
Testing different schedules of vaginal radiation after hysterectomy
This trial compares different “fractionation” schedules (how often and how many treatments) of vaginal brachytherapy radiation given after surgery for certain early-stage endometrial cancer. It may help find a plan that works well while aiming to control side effects.
Baltimore, MarylandAges 18 years+ - NCT03830788Recruiting
Radiation options for early prostate cancer-related erections
This study compares two radiation treatments—seed brachytherapy and stereotactic body radiotherapy—to see which better preserves erections in men with early- to mid-risk prostate cancer. It’s designed to help patients understand how different curative radiation choices can affect sexual function.
AlbiAges 18 years+ - NCT03861507Recruiting
Power ultrasound helps locate prostate treatment needles
This trial studies whether a special ultrasound method (power Doppler ultrasound) can better guide where needles go during high-dose-rate radiation treatment for prostate cancer. The goal is to improve targeting during the procedure while you receive standard treatment.
London, OntarioAges 18 years+ - NCT03861676RecruitingEarly Phase 1
PET-guided targeted radiation for early prostate cancer
This early-phase study tests a precise, targeted radiation treatment for prostate cancer, using a special PET scan to help plan exactly where to treat. It may help reduce the amount of radiation to surrounding tissues while treating the cancer.
Baltimore, MarylandAges 18–100 - NCT04100174RecruitingPhase 2
HDR radiation boost for prostate cancer during standard treatment
This study tests adding a targeted “boost” of HDR (high-dose-rate) internal radiation to the prostate along with standard external beam radiation. It may help improve cancer control while keeping the treatment focused on the area seen on scans and biopsy.
Montreal, QuebecAges Any age - NCT04583254RecruitingPhase 2
Shorter radiation plan for certain early cervical cancers
This trial tests a feasibility (“can it be done safely?”) approach that delivers radiation in a shorter schedule for some cervical cancer patients. It also uses weekly cisplatin chemotherapy and includes a radiation procedure called brachytherapy to improve treatment effectiveness.
Kelowna, British ColumbiaAges 18 years+ - NCT05053555Recruiting
High-dose radiation treatment for hard-to-remove liver tumors
This study uses a form of targeted radiation placed inside/near the liver to treat liver tumors that can’t be surgically removed. It’s meant to shrink or control tumors, especially when they sit near blood vessels or other sensitive organs.
Houston, TexasAges 19 years+ - NCT05608213RecruitingPhase 3
Lenvatinib plus radiation seeds vs lenvatinib alone for liver cancer
This Phase 3 trial compares lenvatinib plus implanted radiation seeds versus lenvatinib alone in people with liver cancer that no longer responds to TACE. It aims to improve how long patients can control the cancer inside the liver.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for brachytherapy?
- Yes. Clin2 currently lists 97 recruiting brachytherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brachytherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brachytherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.