Clinical trials
Brain Disorder clinical trials
Below are recruiting brain disorder clinical trials, each written for real people, not researchers. We’re tracking 304 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06810310RecruitingPhase 2
Psilocybin for motivation in opioid use disorder
This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid use disorder stay motivated in recovery. It uses brain scans to see how psilocybin affects brain areas linked to motivation.
Philadelphia, PennsylvaniaAges 18–60 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06391684Recruiting
Brain flexibility in autistic and non-autistic adults
This study looks at how the brain predicts and adapts in autistic and non-autistic people. Participants will have MRI scans and do simple tasks to help researchers understand flexibility in thinking.
GrenobleAges 18–50 - NCT06004115RecruitingPhase 4
Brain scanning study for depression and anxiety
This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.
Tulsa, OklahomaAges 18–65 - NCT05598034Recruiting
Brain stimulation with tDCS for moderate depression
This study tests whether a noninvasive brain stimulation called tDCS can improve depression symptoms. It also uses MRI scans, aiming to understand how brain changes may relate to symptom improvement.
Los Angeles, CaliforniaAges 20–55 - NCT06906276Recruiting
Brain activity during walking in atypical Parkinson's
This study looks at brain activity while walking in people with atypical Parkinsonian syndromes like PSP or MSA. It may help understand how these conditions affect walking and balance.
Solna, SolnaAges Any age - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT06823492Recruiting
Early life and brain study
This study looks at how your early life experiences may affect your brain and behavior. You would visit the University of Manchester for assessments and help researchers understand these connections.
ManchesterAges 18–25 - NCT06942559Recruiting
Brain stimulation for treatment-resistant OCD
This trial tests a new type of brain stimulation (TMS) that is timed to your brain's natural rhythms, targeting a part of the brain linked to OCD. It may help people whose OCD has not improved with standard treatments.
Toronto, OntarioAges 18–65 - NCT06951659Recruiting
Balance and vision study after brain tumor surgery
This study looks at how brain tumors and their surgery can affect your sense of balance and vision. You will be asked to do some simple tests to help researchers understand these changes.
Perth, Western AustraliaAges 18–80 - NCT07552909Recruiting
Home Digital Therapy for ADHD in Children
This study tests whether a digital therapy program done at home can help children with ADHD improve focus and attention. If it works, it could offer families a convenient treatment option without medication.
Shanghai, Shanghai MunicipalityAges 7–11 - NCT07517172Recruiting
Brain Stimulation Patch for Jaw Pain: Home Treatment Study
This study tests whether a small, stick-on electrical patch placed on your ear can reduce temporomandibular disorder (TMD) jaw pain when used at home. You would apply the patch yourself and complete surveys about your pain to help researchers learn if this non-invasive approach is safe and feasible.
Minneapolis, MinnesotaAges 18–65 - NCT07050862Recruiting
Personalized brain stimulation to help veterans quit smoking
This study tests a personalized brain stimulation treatment to help veterans quit smoking. It uses magnetic pulses to target brain areas involved in addiction, which may reduce cravings and make it easier to stop.
Charleston, South CarolinaAges 18–70 - NCT06892847Recruiting
Brain stimulation for anxiety and depression in youth
This study tests if a non-invasive brain stimulation technique called TMS can help reduce symptoms of anxiety or depression in children and teens. It involves sessions where a magnetic field is used to gently stimulate parts of the brain, and is designed for young people aged 6 to 18 who have been diagnosed with these conditions.
Calgary, AlbertaAges 6–18 - NCT06136247Recruiting
Brain & thinking tests in opioid use disorder
This study tests whether brain scans and thinking tests can help understand opioid use disorder. It is for people on stable buprenorphine or methadone treatment.
Philadelphia, PennsylvaniaAges 18–60 - NCT05770544RecruitingPhase 2/Phase 3
Entrectinib for ROS1 fusion cancers with matching gene test
This trial studies entrectinib, a targeted pill, in people whose cancer has a specific gene change called ROS1 fusion. It may help by shrinking tumors that depend on this ROS1 gene switch, and the study requires starting with a new tissue sample and treatment monitoring.
BelfastAges Any age - NCT05892744RecruitingPhase 4
Testing brain scans to help choose depression treatment
This trial studies how brain signals measured by MRI and EEG may help doctors choose the best treatment for depression. It focuses on people with early-onset, long-lasting or recurring major depression, and tests whether these “brain biomarkers” track with treatment choice and response.
Austin, TexasAges 18–65 - NCT07247344Recruiting
Depression in hospitalized teens: a brain study
This study looks at brain and behavior in teens aged 10–20 who are hospitalized for depression or bipolar disorder. It aims to better understand the condition and may help guide future treatments.
Nanjing, JiangsuAges 10–20 - NCT07127913Recruiting
Closed-loop brain stimulation for hard-to-treat bipolar depression
This trial tests a closed-loop deep brain stimulation system for people with bipolar II disorder whose depression has not responded to standard treatments. The device sends targeted electrical pulses to the brain based on real-time activity, aiming to reduce depression symptoms.
San Francisco, CaliforniaAges 22–70 - NCT05682248Enrolling by invitation
Testing a brain assessment and stimulation system for unconsciousness
This trial studies a device and plan to assess brain function and deliver an intervention in people who are in a coma, minimally conscious state, or unresponsive arousal state after brain injury, stroke, or lack of oxygen. If you qualify, it may help doctors understand and potentially improve brain function over time.
BeijingAges 14–80 - NCT04534777Recruiting
Tests ways to predict recovery after brain injury
This study looks at different ways to predict how people with severe disorders of consciousness might recover after a brain injury. It may help doctors better estimate prognosis and improve care planning.
ParisAges 18–80 - NCT06512324Enrolling by invitation
TMS with remote viewing for depression and anxiety
This trial tests whether adding 'remote viewing' (a technique where a person tries to perceive a distant target) to standard TMS brain stimulation can improve depression and anxiety symptoms. It is for people already getting TMS and who can attend weekly visits.
Encinitas, CaliforniaAges 12 years+ - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age
Hear when a new Brain Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for brain disorder?
- Yes. Clin2 currently lists 304 recruiting brain disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.