Brain Disorder clinical trials

Brain stimulation study for alcohol use with mild brain injury

This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.

A new noninvasive test for small bowel sensation

This study is developing a new, noninvasive test to measure how the small intestine senses stimulation. It aims to create a 'small intestine stress test' that may help better understand and someday diagnose gut sensitivity issues.

Advanced Space-time Resolved Techniques for Functional Neuroimaging at 7 Tesla MRI

Brain training for opioid use disorder

This trial tests a brain-training program for people with opioid use disorder. It uses an EEG headset to measure brain activity while you do computer exercises, and aims to see if this training can help recovery.

Ketone drink for alcohol withdrawal

This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.

Deep brain stimulation for severe OCD using targeted electrodes

This study tests a deep brain stimulation (DBS) treatment device for adults with severe, long-lasting obsessive-compulsive disorder (OCD) that has not improved with standard treatments. It may help reduce OCD symptoms and improve daily functioning when medications and therapy have not worked.

Brain stimulation for young adults with depressive symptoms

This study uses a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) to see if it can improve how the brain and heart work together in people aged 18 to 30 who have mild depressive symptoms. The goal is to understand if this treatment could help with mood regulation.

Deep brain stimulation outcomes in Parkinson's disease

This study looks at factors that predict how well deep brain stimulation (DBS) works for people with Parkinson's disease. If you are considering DBS, joining this research could help doctors better understand who benefits most from the procedure.

Online brain testing for people with neurological conditions

This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.

Brain and eye tests of facial emotion recognition in autism

This study uses brain and eye measurements to understand how people recognize facial expressions, including in autism and related conditions. It may help researchers find markers that better explain autism-related symptoms and differences in processing emotions.

Study of congenital muscle disease patients and their families

This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.

tMS for impulsivity in borderline personality disorder

This trial studies whether magnetic brain stimulation (tMS) can reduce impulsive symptoms in people with borderline personality disorder. It may help by changing how brain networks involved in impulse control work.

Testing brain stimulation for depression and related symptoms

This trial studies a non-invasive brain stimulation treatment for people with depression or related symptoms that haven't improved with standard treatments. The goal is to see how well it works in real-world settings.

Improving cognitive rehab for veterans with concussion and PTSD

This trial tests a program to help veterans with memory, attention, or thinking problems after a mild concussion (mTBI) and with PTSD. It also looks at depression and sleep issues. The goal is to improve thinking and daily life.

Online treatment for kids with stomach pain

This study tests an internet-based program to help children and teens with certain long-term stomach conditions, like irritable bowel syndrome (IBS) or ongoing stomach pain. It aims to see if online tools can reduce symptoms and improve daily life.

Validating eye tests for mild brain injury

This study looks at eye tests for people who had a mild brain injury (mTBI) in the last 1 to 6 months. It aims to better understand and measure eye movement problems that can happen after such an injury.

Sleep study testing breathing and blood flow in healthy adults

This study looks at how your brain blood flow and breathing change during sleep under normal oxygen and reduced oxygen. It will only include healthy adults so researchers can learn what “intermittent hypoxia” does to the body in people without medical problems.

Using brain stimulation to help restore consciousness

This trial tests whether electrical stimulation of a deep brain area can improve awareness in people who have been in a coma-like state for at least 3 months after a brain injury. It aims to help those who have limited or no ability to communicate or use objects.

TBI screening in substance use treatment

This study tests a new way to screen for traumatic brain injury (TBI) among people receiving substance use treatment. If you are in outpatient therapy for substance use, you may be able to join.

Brain stimulation surgery for OCD using a guided DBS system

This trial studies whether deep brain stimulation surgery—guided using special scans—can reduce severe obsessive-compulsive disorder (OCD) symptoms. It may help people whose OCD has not improved enough with standard medicines and therapy.

Deep brain stimulation for movement problems in children with cerebral palsy

This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.

Bone marrow cell transplant for cerebral palsy from brain hypoxia

This trial tests whether transplanting bone marrow cells can help children with spastic cerebral palsy caused by a lack of oxygen to the brain. It may improve movement and daily function.

Brain activity study for severe OCD before DBS surgery

This study looks at how the brain processes approach and avoidance in people with severe OCD that hasn't improved with standard treatments. It aims to understand brain patterns that could help guide a future treatment called deep brain stimulation (DBS).

Virtual reality exercises for new attention problems after brain injury

This study tests whether virtual reality (computer-generated) exercises can improve attention after a recent brain injury, most often stroke. You may be eligible if your brain injury happened within the last month and testing shows measurable attention difficulties.