Clinical trials
Brain Injuries clinical trials
Below are recruiting brain injuries clinical trials, each written for real people, not researchers. We’re tracking 460 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06453733Recruiting
Non-invasive brain pressure monitor for TBI
This trial tests a new, non-invasive way to monitor pressure inside the skull for people with traumatic brain injury. It compares the new device to the standard invasive method already being used in your care.
London, EnglandAges 16–99 - NCT04459806Recruiting
Study dose timing to improve care for brain injury
This trial studies how to time medication or treatment doses when a person has serious brain injury, using measurements from a pressure monitor in the skull. It may help doctors manage brain swelling and pressure more effectively.
Monza, MBAges 18–80 - NCT06429007Enrolling by invitationPhase 1
Metformin for infants after brain injury from HIE
This trial tests whether metformin, a common diabetes medicine, can help heal brain injury in infants who had HIE (lack of oxygen at birth) and were treated with cooling. It aims to see if the drug is safe and possible to give to babies between 3 and 6 months old.
Boston, MassachusettsAges 3 months–6 months - NCT06381674Recruiting
Wearable tech for balance rehab after concussion
This study tests whether a wearable device can help people with balance and vision problems after a mild concussion. You will use the device to guide your own exercises and help improve your recovery.
Portland, OregonAges 18–60 - NCT06368648Recruiting
Study of a new forehead sensor for brain pressure monitoring
This study tests a new sensor that measures brain pressure from outside the head. It is for people who are already in the hospital getting their brain pressure and blood pressure monitored continuously.
Phoenix, ArizonaAges 18 years+ - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT06245434Recruiting
Circadian rhythms during coma awakening
This study looks at how the body's internal clock (circadian rhythm) changes as people wake up from a coma. Researchers hope to learn more about recovery patterns to improve care for patients with brain injuries.
Bron, LyonAges 17 years+ - NCT06241209Recruiting
Vision rehab for hemianopsia after stroke or brain injury
This study tests a vision rehabilitation program for people who lost part of their vision on the same side in both eyes after a stroke or brain injury. The program uses flashing lights to help retrain your brain, so it is important that you do not have seizures triggered by lights.
Edmonton, AlbertaAges 18 years+ - NCT06222450Recruiting
Vestibular rehab app for dizziness after mild brain injury
This study tests a smartphone app with exercises to help improve balance and dizziness in people who have had a mild traumatic brain injury. You may be eligible if you are still experiencing dizziness or balance problems.
Tampa, FloridaAges 18 years+ - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06195345Recruiting
Brain oxygen study for children having an MRI
This study looks at oxygen levels in the brains of children and young adults (birth to 18 years) during a standard MRI. The goal is to learn more about how the brain works, and it only adds a few minutes to your child's regular MRI scan.
Los Angeles, CaliforniaAges 1 minute–18 years - NCT06142435Recruiting
Eye scan to detect and monitor mild brain injury
This study uses a retinal scanner to see if it can detect and track brain injury after a mild head trauma (concussion). If you are between 18 and 45 years old and had a head injury within the past two weeks, this test might help doctors learn more about your injury without invasive procedures.
Boston, MassachusettsAges 18–45 - NCT06148324Recruiting
Wellness program for traumatic brain injury recovery
This study tests a wellness program for people who had a moderate or severe traumatic brain injury (TBI) at least a year ago. The program is done online, so you can join from home, and it aims to help you with your recovery and well-being.
New York, New YorkAges 18–70 - NCT06098833RecruitingPhase 2
Sildenafil for newborn brain injury after birth asphyxia
This trial tests whether a liquid form of the medicine sildenafil can help repair brain damage in newborns who had a difficult birth and were treated with cooling. If your baby meets the cooling criteria and has brain injury on an MRI, this study may offer an additional treatment option.
Denver, ColoradoAges birth–2 days - NCT06065046RecruitingPhase 2
Baricitinib for traumatic brain bleeding
This trial tests if baricitinib, an anti-inflammatory drug, can help people with bleeding in the brain from a head injury. It is for adults with moderate to severe traumatic brain injury who are not immediately having surgery.
Xi'an, ShaanxiAges 18–80 - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT03578003Recruiting
Bright morning light to improve sleep in veterans
This study tests whether using bright morning light can improve sleep quality in veterans. You may be able to join if you’re not already using a light box and you don’t have certain eye or mood conditions.
Portand, OregonAges 18 years+ - NCT05933629Recruiting
Training mental health providers to deliver an online TBI group program
This study helps test whether community mental health clinicians can learn and successfully deliver an online emotion-regulation group program for people with traumatic brain injury (TBI). It may help improve access to structured support when in-person group care is hard to reach.
New York, New YorkAges 18 years+ - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05728840Recruiting
Virtual reality exercises for new attention problems after brain injury
This study tests whether virtual reality (computer-generated) exercises can improve attention after a recent brain injury, most often stroke. You may be eligible if your brain injury happened within the last month and testing shows measurable attention difficulties.
LausanneAges 18 years+ - NCT05741411Recruiting
Text-and-phone support after concussion for teens
This study tests whether a phone-based (mHealth) handoff and follow-up can help teens after a concussion, especially those at higher risk of long-lasting symptoms. It uses smartphone check-ins and coordination between emergency and specialty care.
Philadelphia, PennsylvaniaAges 13–18 - NCT05683145Recruiting
Better sleep for people with moderate or severe TBI
This trial studies an approach to improve insomnia (trouble falling or staying asleep) in people who had a moderate-to-severe traumatic brain injury at least one year ago. If you qualify, it may help you restore more regular, efficient sleep after TBI.
Aurora, ColoradoAges 18–60 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT05426967Recruiting
Brain stimulation for depression after mild traumatic brain injury
This trial studies a noninvasive brain treatment (rTMS) to reduce depression symptoms in people with past mild traumatic brain injury from military service. It may help by changing brain activity, while also requiring stable mental health care and regular follow-up.
Palo Alto, CaliforniaAges 18–55
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Common questions
- Are there clinical trials for brain injuries?
- Yes. Clin2 currently lists 460 recruiting brain injuries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain injuries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain injuries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.