Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,066 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06418594RecruitingPhase 2
Drug combo for HER2-negative breast cancer brain metastasis
This trial tests a combination of two drugs (adebrelimab and apatinib) plus chemotherapy for women with HER2-negative breast cancer that has spread to the brain. It aims to see if this treatment can help shrink or control brain tumors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03458676Recruiting
MRI results to help guide brain tumor biopsy
This study checks whether advanced brain MRI images can help doctors choose the best spot to biopsy suspected or proven primary brain tumors. It may help make biopsies safer and more accurate before tissue diagnosis.
Houston, TexasAges 18 years+ - NCT06221722Recruiting
Brain scan study for treating constipation
This trial uses brain scans to see if doctors can predict how well constipation treatments will work. It is for adults with functional constipation, but only if they have no other digestive problems or medical implants.
Yinchuan, NingxiaAges 18–45 - NCT06747728Recruiting
Bevacizumab before surgery for new high-grade brain tumors
This trial tests whether giving bevacizumab (a drug that blocks blood vessel growth) before surgery helps treat newly diagnosed high-grade gliomas. It may be an option for adults who have not had prior anti-angiogenic therapy.
Zhengzhou, HenanAges 18 years+ - NCT06401057Recruiting
Long-term brain function tracking for brain lesions
This study creates a registry to track brain function over time in people with brain lesions. It aims to better understand how the brain works and may help improve future care.
HeidelbergAges 18 years+ - NCT06263660RecruitingPhase 2
Keto supplement for depression with inflammation
This study tests a keto-like supplement to see if it helps change how the brain responds to emotional situations in people with depression and higher inflammation. It involves MRI brain scans and blood tests.
Tulsa, OklahomaAges 18–65 - NCT05872347RecruitingPhase 2
Brain metastasis breast cancer trial with hormone therapy plus SPH4336
This trial tests whether SPH4336, added to standard hormone (endocrine) therapy, can improve outcomes for people with breast cancer that has spread to the brain. It also looks closely at safety and side effects.
Hefei, AnhuiAges 18–75 - NCT06018363RecruitingPhase 1/Phase 2
Cell therapy for recurrent high-grade glioma
This trial tests a new cell therapy (QH104) for people with an aggressive brain tumor called high-grade glioma that has come back or worsened after standard treatment. The therapy targets a specific protein (B7-H3) on tumor cells to try to fight the cancer.
Suzhou, JiangsuAges 18–70 - NCT06163820RecruitingPhase 1/Phase 2
Bevacizumab and immunotherapy with radiation for melanoma brain metastases
This trial tests a combination of a drug that stops blood vessel growth (bevacizumab), immunotherapy, and focused radiation to treat melanoma that has spread to the brain and is causing symptoms. The goal is to see if this approach shrinks tumors and improves outcomes.
Melbourne, VictoriaAges 18 years+ - NCT06715995Recruiting
Light stimulation's effect on brain waves in healthy older adults
This trial tests if a special light (gamma light) can change brain wave patterns in healthy adults over 55. It aims to understand how light might help keep the brain sharp.
Taoyuan, GuishanAges 55 years+ - NCT06913725RecruitingPhase 2
Testing FCN-159 for Brain AVM
This trial tests an oral medication called FCN-159 for people with a high-grade brain AVM that has never bled. The goal is to see if it can shrink the AVM or prevent future problems.
Beijing, Beijing MunicipalityAges 18–60 - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07711990Recruiting
Studying ketone supplements and brain health
This trial tests how a ketone drink affects the brain in healthy middle-aged adults. It may help researchers understand if ketones can support brain function.
Columbus, OhioAges 45–65 - NCT04107285Recruiting
Study brain changes in people with lymphoma after CAR T
This study looks at how thinking and brain function change over time in people with lymphoma who receive CAR T therapy. It may help doctors understand side effects and better support patients during and after treatment.
New York, New YorkAges 18 years+ - NCT05416905Recruiting
Deep brain stimulation for facial dystonia using GPi or STN
This trial studies deep brain stimulation (a surgically placed device that sends targeted electrical signals) to treat idiopathic craniofacial dystonia when medicines or botulinum toxin haven’t helped enough. It compares stimulating two brain targets (GPi versus STN) to see which approach may improve symptoms.
BeijingAges 18–75 - NCT07423936Recruiting
Monitoring brain and organ activity in organ donors
This trial tests special monitors on organ donors after life support is withdrawn, to see how the organs and brain behave. It may help improve organ transplant outcomes.
Vancouver, British ColumbiaAges 19 years+ - NCT07435610Recruiting
Acupuncture for children with stomach pain and related issues
This study tests whether acupuncture can help children with stomach pain or other gut-brain interaction disorders. It may be a good option if your child's current treatments aren't working well enough.
Irvine, CaliforniaAges 8–17 - NCT07318714RecruitingPhase 1/Phase 2
Study of ASP2246 for movement problems after a stroke
This study tests an experimental treatment called ASP2246 for people who have movement problems after a stroke. It aims to see if it can help improve arm and leg function when combined with rehabilitation therapy.
Sendai, MiyagiAges 18–80 - NCT07417072Recruiting
Brain tumor drug testing using 3D models in children
This study creates 3D models from brain tumor tissue of children aged 3-18 to test how different drugs might work against their specific tumor. The goal is to find more personalized treatments.
Florence, FirenzeAges 3–18 - NCT06577402Recruiting
Study on energy and protein in severe brain injury patients
This study measures how your body uses energy and protein if you are in the ICU with a severe brain injury while on a breathing machine. It can help doctors better understand your recovery needs.
Nanjing, JiangsuAges 18–85 - NCT07572240Recruiting
Collagen Peptides for Memory and Focus in Stressed Adults
This study tests whether a collagen supplement (a protein derived from cows) can help improve attention, focus, and memory in adults aged 35–70 who feel stressed but are otherwise healthy. Researchers want to see if this supplement can help with mild cognitive complaints like trouble concentrating.
Nashik, MaharashtraAges 35–70 - NCT07239115RecruitingPhase 3
Levetiracetam to prevent seizures after brain tumor surgery
This trial tests whether the drug levetiracetam can prevent seizures in people who have brain tumor surgery. If you are having surgery to remove a brain tumor and have never had a seizure, this study may help keep you from having one after the operation.
BeijingAges 18–75 - NCT07208279Recruiting
Cognitive Vitality Study: Can Axolt help memory?
This clinical trial is testing whether a special dietary supplement called Axolt can help keep your memory and thinking sharp as you get older. It is for healthy adults 55 and older who live independently and have no major memory problems.
West Palm Beach, FloridaAges 55 years+ - NCT06839547Recruiting
Testing a new drug with radiation for advanced breast cancer brain tumors
This study looks at how well a new anti-tumor drug works when given along with radiation therapy for people whose advanced breast cancer has spread to the brain. It may help the radiation work better and control the cancer longer.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,066 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.