Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07731555Recruiting
Studying the brain barrier in glioblastoma
This study looks at how the brain's protective barrier works in people with glioblastoma. Researchers will study tumor tissue and use special scans to learn more, which might help improve future treatments.
BeaumontAges 18 years+ - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT07718321Recruiting
StimolIrpinia for brain injury rehab: a feasibility trial
This trial tests a new cognitive rehab tool called StimolIrpinia for people recovering from a serious brain injury. It aims to see if the tool is acceptable and helpful for improving thinking and memory.
Sant'Angelo dei Lombardi, AVAges 18–75 - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT07711990Recruiting
Studying ketone supplements and brain health
This trial tests how a ketone drink affects the brain in healthy middle-aged adults. It may help researchers understand if ketones can support brain function.
Columbus, OhioAges 45–65 - NCT06146062RecruitingPhase 2
Stem cell therapy for severe traumatic brain injury
This trial tests whether a single infusion of stem cells from donated umbilical cord tissue can help calm inflammation in the brain after severe traumatic brain injury. It is for patients aged 18–50 who need brain pressure monitoring and are not responding to verbal commands 5 days after sedation is stopped.
ClamartAges 18–50 - NCT06628752Recruiting
Deep brain stimulation for severe OCD
This study tests a treatment called deep brain stimulation (DBS) for people with severe OCD that hasn't improved with standard therapies. DBS uses a device to send small electrical pulses to specific parts of the brain to help control symptoms.
Umeå, Västerbotten CountyAges 18–65 - NCT07698431Recruiting
Personalized brain health service for dementia prevention
This trial tests a personalized brain health program for people aged 55-85 who have minor memory or thinking worries but are still mentally sharp. It uses technology like smartphones and computers to help you stay healthy and prevent dementia.
Barcelona, CataloniaAges 55–85 - NCT07698665Recruiting
Ketamine vs dexmedetomidine in scalp block for brain tumor surgery
This trial compares two medicines, ketamine and dexmedetomidine, added to a scalp nerve block during brain tumor removal surgery. The goal is to see which provides better pain control and recovery after surgery.
Cairo, GovernorateAges 20–60 - NCT07688746RecruitingPhase 1
Helping premature babies heal brain injury
This trial tests a treatment for brain injury in premature babies born before 32 weeks. It aims to protect and repair white matter, the part of the brain that helps nerve cells communicate.
San Francisco, CaliforniaAges 3 weeks–5 months - NCT04266574Recruiting
Blood pressure–guided care for older or frail surgical patients
This study tests a goal-based blood pressure treatment approach during major surgery for people at higher risk (often older or frail with high blood pressure). The goal is to see if this BRAIN-targeted strategy can improve how patients do after surgery.
Rozzano, MilanAges 18 years+ - NCT07688356RecruitingPhase 2
Belvarafenib for BRAF-altered brain tumors
This trial tests a drug called Belvarafenib for people with brain tumors that have a BRAF gene change (mutation). The drug targets this specific change to try to shrink or control the tumor. It is for patients whose brain tumor has come back or hasn't responded to other treatments.
SeoulAges 19 years+ - NCT07673770Recruiting
Brain stimulation to improve memory in dementia
This study tests whether a safe, non-invasive brain stimulation technique called TMS (transcranial magnetic stimulation) can help improve memory and thinking in people with dementia. By measuring your brain waves first, researchers hope to tailor the stimulation to your specific needs.
Hamilton, OntarioAges 55 years+ - NCT07677046Enrolling by invitation
Combination therapy for complex dissociative disorder
This trial studies a therapy called Deep Brain Reorienting (DBR) combined with group sessions for people with complex dissociative disorder, such as dissociative identity disorder (DID) or other specified dissociative disorder (OSDD). The goal is to help process trauma in a safe and supportive setting.
Oslo, OsloAges 18 years+ - NCT07664176RecruitingPhase 1
Focused ultrasound plus nivolumab for children with brain tumors
This trial tests if combining focused ultrasound (which opens the blood-brain barrier) with the immunotherapy drug nivolumab can treat relapsed or progressive brainstem gliomas and other high-grade brain tumors in children and young adults.
Washington D.C., District of ColumbiaAges 3–25 - NCT07670195RecruitingPhase 2
BCAAs for concussion recovery in young people
This study tests if a supplement called BCAAs (branched-chain amino acids) can help young people recover from a concussion. It aims to see if BCAAs improve symptoms compared to a placebo.
Havertown, PennsylvaniaAges 11–23 - NCT07664358Recruiting
Predicting lung injury after traumatic brain injury
This study looks at whether a simple blood test measuring fibrinogen and albumin levels can help predict if someone with a traumatic brain injury will develop a serious lung condition called acute respiratory distress syndrome (ARDS). It may help doctors identify patients who need extra monitoring and care.
Tanta, Gharbia GovernorateAges 18 years+ - NCT07659964Recruiting
Rhythmic music and walking study for Alzheimer's
This study tests whether listening to a steady beat (rhythmic music) while walking can improve movement and brain function in people with mild Alzheimer's disease. Healthy volunteers are also needed for comparison.
Boston, MassachusettsAges 50–90 - NCT07657403Recruiting
Brain mapping guided tumor surgery trial
This trial uses a brain connectivity map to help surgeons remove brain tumors while protecting areas that control language, movement, and thinking. It may be an option for people whose tumors are near important brain networks.
BeijingAges Any age - NCT07655583RecruitingPhase 1
Skipping radiation after brain surgery
This study is for people with melanoma or lung cancer that has spread to the brain and who have had surgery to remove the brain tumor. It looks at whether it is safe to skip the usual radiation treatment after surgery, while taking a targeted drug therapy that is known to be effective in the brain.
Houston, TexasAges 18 years+ - NCT06604689Recruiting
AI-guided brain radiation for EGFR-mutant lung cancer with brain mets
This study uses AI to help doctors decide the best way to use brain radiation for people with EGFR-mutant lung cancer that has spread to the brain. It aims to improve treatment planning and outcomes for those already taking a third-generation targeted therapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07650188Recruiting
Brain Stimulation to Help Aging Memory and Thinking
This study tests whether brain and sensory stimulation can help people with early memory loss or mild cognitive changes. Researchers will use non-invasive stimulation techniques to see if they improve thinking and daily function.
Milwaukee, WisconsinAges 45 years+ - NCT06673589Recruiting
Study on brain synchrony during social interaction
This trial looks at how brain activity syncs between people, focusing on those with different levels of social interaction. It may help understand social connection better.
Fairfield, IowaAges 18–50
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.