Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,066 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07385027Recruiting
Brain wave study in romantic couples
This trial uses EEG to study brain activity in romantic couples. It tests how partners' brains connect in different settings and includes a brief pain stimulus on the leg.
Charlestown, MassachusettsAges 20–60 - NCT07103200Recruiting
Decision-making fatigue after traumatic brain injury
This study looks at how making decisions can feel more tiring after a mild or moderate traumatic brain injury compared to people without a brain injury. It uses computer tasks to measure fatigue.
Minneapolis, MinnesotaAges 18 years+ - NCT07655583Recruiting
Skipping radiation after brain surgery
This study is for people with melanoma or lung cancer that has spread to the brain and who have had surgery to remove the brain tumor. It looks at whether it is safe to skip the usual radiation treatment after surgery, while taking a targeted drug therapy that is known to be effective in the brain.
Houston, TexasAges 18 years+ - NCT07742878Recruiting
Vision testing in people with recent brain injury
This study tests a new device called the Traq™ that looks at how well the two eyes work together. It's for people with a recent mild-to-moderate brain injury and for people without one, to see if the device can spot vision changes after injury.
Waukee, IowaAges 12 years+ - NCT07402343RecruitingPhase 2
Tarlatamab for small cell lung cancer brain metastases
This trial tests a new drug, tarlatamab, for people with small cell lung cancer that has spread to the brain. It aims to see if the drug can shrink brain tumors and help you live longer, especially if you have not had brain radiation before.
AmsterdamAges 18 years+ - NCT06991101RecruitingPhase 2
Ruxolitinib with radiation and chemo for new glioblastoma
This trial tests adding ruxolitinib, a targeted drug, to the standard radiation and chemotherapy for newly diagnosed glioblastoma. It aims to see if this combination helps people live longer without their cancer growing.
Miami, FloridaAges 18 years+ - NCT07688746RecruitingPhase 1
Helping premature babies heal brain injury
This trial tests a treatment for brain injury in premature babies born before 32 weeks. It aims to protect and repair white matter, the part of the brain that helps nerve cells communicate.
San Francisco, CaliforniaAges 3 weeks–5 months - NCT07732868Enrolling by invitation
Virtual Reality Therapy for Spinal Cord Injury
This trial tests a virtual reality (VR) program that uses brain-machine interface (BMI) technology to help people with spinal cord injuries regain movement. The program may help your brain and body work together better, potentially improving your recovery.
AveiroAges 18–65 - NCT07731555Recruiting
Studying the brain barrier in glioblastoma
This study looks at how the brain's protective barrier works in people with glioblastoma. Researchers will study tumor tissue and use special scans to learn more, which might help improve future treatments.
BeaumontAges 18 years+ - NCT07416188RecruitingPhase 1/Phase 2
LMP744 drug for returning glioblastoma
This trial tests an experimental drug called LMP744 for people whose glioblastoma has come back. It aims to see if the drug can slow or stop tumor growth by targeting specific proteins in cancer cells.
Bethesda, MarylandAges 18–99 - NCT06999122Recruiting
Testing a new helmet-style brain scanner for stroke bleeding
This trial tests a new type of brain scanner (similar to a helmet) that looks for bleeding in the brain without radiation. It is for people who have had stroke-like symptoms in the last 24 hours and have not yet received treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT07215195Recruiting
Brain injury, sleep, and mental health study
This study looks at how brain injuries affect sleep and mental health in the months after injury. It is for people who have had a stroke, brain bleed, or traumatic brain injury within the past year and are willing to let the research team contact their doctor if needed.
OxfordAges 18 years+ - NCT07718321Recruiting
StimolIrpinia for brain injury rehab: a feasibility trial
This trial tests a new cognitive rehab tool called StimolIrpinia for people recovering from a serious brain injury. It aims to see if the tool is acceptable and helpful for improving thinking and memory.
Sant'Angelo dei Lombardi, AVAges 18–75 - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT04348747RecruitingPhase 2
Vaccine plus pembrolizumab for breast cancer in the brain
This trial studies whether a personalized immune-cell vaccine (dendritic cell vaccine) combined with pembrolizumab can help control brain metastases from certain types of breast cancer. It may help your immune system better recognize and attack cancer cells in the brain.
Tampa, FloridaAges 18 years+ - NCT06322602Recruiting
Brain tumor biopsy with Ommaya reservoir for fluid collection
This study places a small reservoir under your scalp during a brain tumor biopsy to collect fluid samples over time. It may help doctors learn more about your tumor and how it responds to treatment.
Rochester, MinnesotaAges 18 years+ - NCT06595914Enrolling by invitation
Improving education for mild traumatic brain injury
This trial is working to improve how doctors and nurses teach patients about mild traumatic brain injury (mTBI) in the emergency room and after they go home. It may help you get clearer information and support during recovery.
Milwaukee, WisconsinAges 18 years+ - NCT06047379RecruitingPhase 1/Phase 2
Testing NEO212 for brain tumors and metastases
This trial tests a new drug called NEO212 for people with certain brain tumors (like astrocytoma or glioblastoma) or cancer that has spread to the brain from other parts of the body. The goal is to see if it is safe and if it can help shrink or control the tumors.
Beverly Hills, CaliforniaAges 18 years+ - NCT07278440Recruiting
Exercise program for brain tumor patients and their partners
This study tests if a home exercise program can improve mental and physical health for people with brain tumors and their live-in partners. Both of you will be guided through exercise sessions together over video.
Portland, OregonAges 18 years+ - NCT05951777RecruitingPhase 2
Stem cells from your own fat for chronic brain injury
This trial tests whether stem cells taken from your own fat and given through an IV can help people with long-term brain damage from a head injury. It is for adults who have not gotten better with standard treatments.
Houston, TexasAges 18–55 - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03399929Recruiting
Tracking long-term recovery after brain injury or stroke
This study looks at how people do over the long term after a stroke or a traumatic brain injury (brain injury from an accident). It may help researchers understand recovery and improve future support and care.
Encino, CaliforniaAges 18 years+ - NCT03449238RecruitingPhase 1/Phase 2
Pembrolizumab with focused brain radiation for breast cancer brain spread
This trial studies whether pembrolizumab (an immune therapy medicine) plus stereotactic radiosurgery (focused radiation) can better control brain metastases from breast cancer. It may help shrink or slow growth of multiple brain spots with minimal treatment to surrounding tissue.
New York, New YorkAges 19–90
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,066 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.