Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT06055790RecruitingPhase 2
PET scan to find brain tumors from other cancers
This study tests a special PET/CT scan that uses a tracer called 18F-fluciclovine to find brain tumors that have spread from other cancers. It may help doctors see if this scan can better identify these tumors before treatment.
Tucson, ArizonaAges 18–99 - NCT06058351Recruiting
Brain injury aftercare at home
This trial tests a home-based aftercare program for people with acquired brain injury (ABI). It aims to improve recovery by offering multidisciplinary support in your own home.
RotterdamAges 18 years+ - NCT06058988RecruitingPhase 2
T-DXd for people with brain cancer
This trial tests a drug called Trastuzumab Deruxtecan (T-DXd) for people with brain tumors that are either glioblastoma or have spread from other cancers. Doctors will see if T-DXd can shrink tumors or slow their growth, and they will collect tumor tissue during surgery or biopsy to study how the drug works.
New York, New YorkAges 18 years+ - NCT06062628RecruitingEarly Phase 1
Ketamine for severe traumatic brain injury
This study tests whether a low dose of ketamine can help people with severe traumatic brain injury by reducing brain pressure and improving oxygen levels. If you have a brain monitor in place and meet safety criteria, you may be able to join.
Dallas, TexasAges 18 years+ - NCT06076928Recruiting
Brain-computer interface glove for hand recovery after stroke
This trial tests a robotic glove controlled by your brain signals to help improve hand function after a stroke. It is for people who had a stroke at least 16 weeks ago and have some movement in their shoulder and elbow but limited hand control.
Singapore, SingaporeAges 21–85 - NCT06081036Recruiting
Normal brain volumes from fetal MRI scans
This study looks at past fetal MRI scans to create a map of normal brain growth in babies before birth. It may help doctors better understand what healthy brain development looks like.
MarseilleAges 5 months–9 months - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT06099743Recruiting
ASCENT Support Program for Brain Tumor Patients
This trial tests a support program called ASCENT for people recently diagnosed with a malignant brain tumor. It aims to help patients and their families adjust and manage challenges soon after diagnosis.
Boston, MassachusettsAges 18 years+ - NCT06103201RecruitingPhase 1
Special MRI for Traumatic Brain Injury Recovery
This trial uses a special MRI scan to look at how your brain uses energy after a traumatic brain injury. The goal is to better understand brain healing and find new ways to help people recover.
Baltimore, MarylandAges 18–80 - NCT06109909Recruiting
Brain training for light sensitivity after mild head injury
This study tests if a type of brain training called neurofeedback can help reduce sensitivity to light in people who have had a mild traumatic brain injury, also known as a concussion, at least 6 months ago.
Boston, MassachusettsAges 18–65 - NCT06112093RecruitingPhase 1
Magnetic brain stimulation for headaches after a concussion
This study tests whether a non-invasive magnetic pulse treatment (repetitive transcranial magnetic stimulation) can help people with long-lasting headaches following a mild concussion. If you are 18 to 55 years old and have had daily headaches for at least 3 months after your head injury, this study may help find a new way to relieve your pain.
Syracuse, New YorkAges 18–55 - NCT06116942Recruiting
Brain stimulation and computer training for arm recovery after stroke
This trial combines magnetic brain stimulation with computer-based motor training to help improve arm and hand function in people who had a stroke at least 6 months ago. It may be a good fit if you have moderate to severe weakness on one side and can take part in brain-computer interface training.
Leipzig, SaxonyAges 20–80 - NCT06117930Recruiting
Brain tumor and gut bacteria study
This study looks at how the bacteria in your gut might be linked to brain tumors. Researchers want to collect samples (like stool and tissue) during brain surgery to better understand this connection.
Jacksonville, FloridaAges 18 years+ - NCT06127459Recruiting
Virtual reality to help kids with brain injury improve thinking skills
This trial tests if virtual reality exercises can help children aged 8-12 with mild or moderate traumatic brain injury improve their attention and thinking skills. It is designed for children whose challenges were confirmed by a psychologist and who speak Finnish.
OuluAges 8–12 - NCT06136884RecruitingPhase 1
Study of AO-252 for advanced solid tumors with or without brain metastases
This trial tests an experimental oral pill (AO-252) that targets a protein called TACC3 in advanced solid tumors, including those that have spread to the brain. It is for people whose cancer has a specific genetic change (TP53 mutation) or who have prostate cancer, and who have already tried other treatments.
Detroit, MichiganAges 18 years+ - NCT06138340Recruiting
How anesthesia affects brain networks in people with glioma
This study looks at how different anesthetics change brain connections during surgery for a type of brain tumor called glioma. It may help doctors choose the best anesthesia for your surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06146062RecruitingPhase 2
Stem cell therapy for severe traumatic brain injury
This trial tests whether a single infusion of stem cells from donated umbilical cord tissue can help calm inflammation in the brain after severe traumatic brain injury. It is for patients aged 18–50 who need brain pressure monitoring and are not responding to verbal commands 5 days after sedation is stopped.
ClamartAges 18–50 - NCT06159335RecruitingPhase 3
PET/MR scan for brain metastasis imaging
This trial uses a special PET/MR scan with a radioactive tracer to help tell the difference between tumor regrowth and changes from radiation treatment in people with brain metastases. It may help doctors make better treatment decisions.
Madison, WisconsinAges 18 years+ - NCT06162091Recruiting
Understanding recovery after severe brain injury
This study is for adults who recently had a severe brain injury (within the last 3 months) and are in the early stages of recovery. Researchers want to learn more about what affects recovery and how to improve outcomes.
MessinaAges 18 years+ - NCT06165653Recruiting
Guided meditation during radiation for brain tumors
This trial tests whether guided meditation can help people with brain tumors feel better during radiation therapy. You'll be randomly assigned to either meditation sessions or standard care, and researchers will see how it affects your well-being.
Salt Lake City, UtahAges 18 years+ - NCT06184295Recruiting
Robotic balance training for better balance after brain injury
This study tests whether training on a robotic device can help improve balance and posture for people who had a traumatic brain injury (TBI) within the last 6 months to 5 years. It may help if you have some balance issues and can stand without support for 5 minutes.
West Orange, New JerseyAges 18–65 - NCT06188364RecruitingEarly Phase 1
Helping caregivers of traumatic brain injury patients
This trial tests if mobile health support (texts and calls) helps caregivers of people with traumatic brain injury after rehab. You may join as the main caregiver if you supervise daily care and have a smartphone or can get one.
Richmond, VirginiaAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.