Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07463027Enrolling by invitation
Veteran brain injury rehab with integrated care
This trial tests a 3-week rehabilitation program for veterans with traumatic brain injury and other conditions. It aims to improve recovery through team-based care.
Milwaukee, WisconsinAges 18–65 - NCT07373951Enrolling by invitation
Predicting cancer gene status from MRI scans in brain metastasis
This trial uses brain MRI scans and deep learning to predict whether non-small cell lung cancer that has spread to the brain has certain gene changes (EGFR or ALK). Knowing this may help guide treatment without needing additional tissue testing.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07296783Enrolling by invitation
Tracking recovery in older adults with traumatic brain injury
This study observes older adults (65+) who have had a recent head injury to understand how they recover over time. It may help improve care for seniors with brain trauma.
San Francisco, CaliforniaAges 65 years+ - NCT06981897Enrolling by invitation
Early cognitive rehab for moderate brain injury recovery
This trial tests whether starting cognitive rehabilitation early after a moderate traumatic brain injury helps improve thinking, memory, and daily function. If you're an adult with a moderate brain injury who is medically stable, this study may help you regain skills faster.
Cairo, ManialAges 18 years+ - NCT06923683Enrolling by invitation
Social skills treatment for brain injury
This trial tests a treatment called T-ScEmo for people with brain injury who have trouble with social skills and emotions. The treatment involves you and a support person (like a partner or close friend) working together to improve social understanding and behavior.
Boekel, North BrabantAges 18–70 - NCT06888219Enrolling by invitation
Acupuncture for Swallowing and Tube Removal After Brain Injury
This study tests if acupuncture on the ear and body can help people with severe brain injuries regain the ability to swallow safely and have their breathing tube removed. It's for patients who are at least 1 month but no more than 3 months after a stroke or brain bleed.
FlorenceAges 18 years+ - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+ - NCT06800040Enrolling by invitation
Group memory training for brain injury survivors
This trial tests a group memory training program for people who have had a brain injury at least 6 months ago and still have memory problems. The training is in Norwegian and aims to help improve memory skills.
TromsøAges 18–75 - NCT06699953Enrolling by invitation
EEG study of fentanyl and how it relates to drug liking
This study looks at how fentanyl affects brain waves (EEG) and whether those brain changes are linked to how much a person likes the drug. If you are having surgery with fentanyl, you may be able to join.
Palo Alto, CaliforniaAges 18 years+ - NCT06688162Enrolling by invitation
Minimally invasive surgery for small brain bleeds
This trial tests a less invasive surgery to remove small blood clots (20–30 ml) in the basal ganglia, a deep part of the brain. It may help people who are awake but have a reduced level of consciousness after a recent brain bleed.
BeijingAges 18–80 - NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT06115291Enrolling by invitation
Smell training study for adults with smell loss
This study tests whether a daily smell training routine can help improve your sense of smell. It is open to adults with any kind of smell loss or problem, including those with conditions like COVID-19 or head injury, but not certain brain diseases.
Kansas City, KansasAges 18–80 - NCT05917665Enrolling by invitation
Test biomarkers in special forces course instructors
This study looks for early body and brain “signals” (biomarkers) that may show how brain injury happens and how recovery works over time. It is only open to instructors of a specific Special Forces course.
Fort Bragg, North CarolinaAges 18 years+ - NCT05863897Enrolling by invitation
Online program to help long-term fatigue after brain injury
This trial tests an online, blended coaching program for severe fatigue that lasts at least 6 months after a stroke or traumatic brain injury. It may help reduce fatigue by supporting self-management using an internet-based approach.
Wijk aan Zee, North HollandAges 18–70 - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
San Francisco, CaliforniaAges 18–65 - NCT05786729Enrolling by invitationPhase 1/Phase 2
Aerobic exercise program after traumatic brain injury
This trial tests whether a supervised aerobic exercise plan is safe and helpful for people recovering from traumatic brain injury (TBI). It may help improve physical fitness and functioning through regular walking and aerobic training.
Bakersfield, CaliforniaAges 18–60 - NCT05616910Enrolling by invitationPhase 2
Inhaled nitric oxide for microvascular problems after brain injury
This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.
Philadelphia, PennsylvaniaAges 18–75 - NCT05116137Enrolling by invitation
Exercise therapy to build muscle after glioblastoma
This trial studies whether a resistance (strength-building) exercise program can help survivors of glioblastoma keep or increase their muscle mass. If you are able to safely exercise, it may support recovery and overall strength after treatment.
Halifax, Nova ScotiaAges 18 years+ - NCT04982731Enrolling by invitation
Testing reassurance support after a concussion in teens
This study looks at whether a specific reassurance program (“Positive Assurance”) helps teens recover better after a mild concussion. Teens are checked for concussion symptoms, then assigned to different support approaches to see which helps most.
Falls Church, VirginiaAges 13–21 - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT04002505Enrolling by invitation
Study for low-risk head injury after a bump to the head
This trial studies people with a recent, blunt head injury who are considered low risk and may be getting a head CT scan. It may help improve how doctors decide when CT scans are needed after a concussion or possible brain bleeding.
Rochester, MinnesotaAges 18–65 - NCT03502967Enrolling by invitationEarly Phase 1
Hyperpolarized carbon-13 brain scan for recent traumatic brain injury
This early study tests a special brain imaging scan that looks at brain metabolism after a recent concussion/traumatic brain injury (TBI). It may help researchers understand what’s happening in the brain soon after injury.
Dallas, TexasAges 18–60 - NCT03170141Enrolling by invitationPhase 1
T-cell therapy for recurrent brain tumor
This Phase 1 study tests modified immune T-cells to treat recurrent glioblastoma (a fast-growing brain tumor) that can be seen on scans. Because it’s early-stage, the goal is mainly safety, but you may be helping researchers understand if the treatment can shrink tumors.
Shenzhen, GuangdongAges 6–70 - NCT07752784Enrolling by invitationPhase 3
Tau brain imaging in people with mild thinking changes or Alzheimer's
This study uses a special PET scan to take pictures of abnormal tau protein in the brain. It aims to see if the scan results match what is found in brain tissue after death, which could help improve diagnosis of Alzheimer's and related conditions.
Beijing, Beijing MunicipalityAges 50 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.