Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05771844Recruiting
Home sleep treatment for older adults with memory changes
This study tests whether a home sleep therapy program can improve symptoms in older adults who have amnestic mild cognitive impairment (MCI) or help compare to people without MCI. It may be useful if your main issue is memory or thinking changes and you also have sleep problems.
Winston-Salem, North CarolinaAges 40–85 - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT07396896Recruiting
A study on brain tumors and weight gain after treatment
This trial tests a diet therapy for young people who have gained a lot of weight after treatment for a certain type of brain tumor. The goal is to see if the diet can help manage obesity related to the tumor or its treatment.
Florence, FlorenceAges 7–30 - NCT07390136Recruiting
Brain development study for babies with and without early brain injury
This study looks at how babies' brains develop, comparing infants who had a brain injury around birth with healthy babies. It could help understand early thinking and learning abilities.
Madison, WisconsinAges 3 months–2 years - NCT07396103Recruiting
New approach to reduce breathing pauses in preemies
This study tests a new way to reduce the number of times a preemie baby stops breathing (apnea). It's for babies born early who have apnea but are not on a breathing machine.
Santiago, Santiago MetropolitanAges Up to 4 weeks - NCT07391215RecruitingPhase 1/Phase 2
Paxalisib for newly diagnosed glioblastoma after standard treatment
This trial tests a drug called paxalisib in people with a newly diagnosed aggressive brain tumor (glioblastoma) who have just finished standard radiation and chemotherapy. The goal is to see if adding paxalisib can help prevent the tumor from coming back by targeting a specific pathway in the cancer cells.
SuttonAges 16 years+ - NCT07396454RecruitingPhase 2
Radiation plus anlotinib for HER2-negative breast cancer brain metastases
This trial tests whether adding anlotinib (a targeted therapy) to standard radiation can better control breast cancer that has spread to the brain. It is for people with HER2-negative breast cancer and at least one brain tumor seen on MRI.
NanjingAges 18–70 - NCT07380412Recruiting
Supplement study for ADHD med side effects
This trial tests if a dietary supplement can help reduce common side effects of stimulant medications for ADHD, like trouble sleeping or feeling irritable. If you take a stable dose of ADHD medication and are dealing with these issues, you may be able to join.
Las Vegas, NevadaAges 18–55 - NCT06835426Recruiting
Imaging removed tissue during cancer surgery
This study tests a high-resolution PET-CT scanner that takes pictures of tissue removed during surgery to help doctors see if all the cancer has been removed. You might qualify if you are having surgery for a range of cancers including breast, prostate, thyroid, skin, gastrointestinal, or brain tumors.
Ghent, Oost VlaanderenAges 18 years+ - NCT07384884Recruiting
Surgery and laser for glioblastoma on both sides
This study tests a treatment for glioblastoma that affects both sides of the brain. It combines surgery to remove as much tumor as possible with a laser treatment (LITT) to destroy the smaller tumor on the other side.
LondonAges 18–80 - NCT07380477Recruiting
Infection risk study for external ventricular drains
This trial looks at whether the fluid from your brain drain (called CSF) can help predict infections. It compares samples taken from different spots on the drain to find better ways to catch infections early.
CopenhagenAges 18 years+ - NCT07387107Recruiting
Reducing stress with virtual reality and special sounds
This study tests if a short session of virtual reality and specially designed sounds (binaural beats) can help healthy adults feel less stressed. Volunteers attend a single 60-minute session.
Bad NauheimAges 18 years+ - NCT07380204Recruiting
Measuring Hsp90 in the brain with a PET scan
This study uses a special PET scan to measure a protein called Hsp90 in the brain. It aims to understand how Hsp90 levels differ in healthy people and those with Parkinson's, Alzheimer's, or ALS, which may lead to new treatments.
Leuven, Vlaam-BrabantAges 18–70 - NCT07386769Recruiting
Brain activity during social interaction in opioid use
This study looks at how the brain works during social interactions in people who use opioids regularly. It may help researchers understand how opioid use affects the way you connect with others.
La Jolla, CaliforniaAges 18 years+ - NCT07383649RecruitingPhase 2
Anti-CMV therapy for breast cancer with brain metastases
This trial tests a treatment targeting a common virus (CMV) in breast cancer that has spread to the brain. The goal is to see if anti-CMV therapy can shrink or slow these brain tumors.
Houston, TexasAges 18 years+ - NCT06691490Recruiting
Brain activity and daily physical activity study
This study looks at how your brain's perception of effort is linked to how much physical activity you do. It uses EEG (a cap that records brain waves) and fMRI (an MRI that shows brain activity) to understand this connection.
La TroncheAges Any age - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT05004610RecruitingPhase 2
Hypertonic lactate treatment after cardiac arrest
This trial studies whether giving a specific IV fluid (hypertonic lactate) soon after resuscitation from cardiac arrest can improve recovery. It is for adults who remain in a deep unresponsive state after return of spontaneous circulation.
Brussels, BelgiumAges 18 years+ - NCT05818410Recruiting
Brain and tech training after below-knee leg loss
This study looks at how your brain works with assistive technology after losing a leg below the knee. It may help researchers improve how prosthetic devices feel and function by measuring brain and movement signals during training.
BrusselsAges 18–65 - NCT07378332Enrolling by invitation
Memory study using brain stimulation
This trial uses brain stimulation to study how memory works. It may help people undergoing epilepsy monitoring learn more about their memory.
Chicago, IllinoisAges 18 years+ - NCT07374913Recruiting
Study of COL4A1 and COL4A2 gene mutations
This study looks at people with a mutation in the COL4A1 or COL4A2 genes, which can cause problems in small blood vessels throughout the body. It aims to learn more about the condition and may also include family members who carry the mutation or who can serve as healthy controls.
Florence, FIAges Any age - NCT07375485Enrolling by invitation
Occupational therapy for brain injury recovery at home
This trial explores how occupational therapy can help people with brain injuries stay engaged in daily life. Researchers want to learn from therapists working in home or community settings to improve care.
Denver, ColoradoAges 18 years+ - NCT07365696Recruiting
Fatigue and brain fog after stem cell transplant
This trial looks at the causes of fatigue and cognitive problems (like memory or concentration issues) after a stem cell transplant. It uses old PET scans to study possible damage in the brain.
StockholmAges 20–75 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.