Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04684368RecruitingPhase 2
New treatment study for children and young adults with NGGCT brain tumors
This Phase 2 study tests a new treatment approach for certain brain tumors called NGGCT in children and young adults. It may help improve outcomes by targeting tumors in specific brain locations and using tumor marker tests to guide care.
Birmingham, AlabamaAges 3–29 - NCT04692324Recruiting
Test spinal fluid tests to help identify brain tumor types
This study looks at spinal fluid (cerebrospinal fluid, or CSF) to find markers that may signal a brain or spinal tumor or related abnormal growth. If you have a suspected tumor near the CSF spaces, these results may help doctors better classify what’s going on.
Rochester, MinnesotaAges Any age - NCT04696523RecruitingPhase 2
Xenon gas for brain injury after a ruptured brain aneurysm
This Phase 2 study tests whether xenon gas can reduce brain injury after an aneurysmal subarachnoid hemorrhage (a bleeding caused by a brain aneurysm). It aims to help people who are very sick right after the bleeding by improving brain function outcomes.
Helsinki, HelsinkiAges 18 years+ - NCT04699773Recruiting
Laser treatment then focused radiation for new brain gliomas
This trial studies a two-step treatment for newly diagnosed high-grade glioma: first laser treatment (LITT) to target the tumor, followed by a shorter, more focused course of radiation. It may help shrink or control the tumor while limiting treatment time.
Baltimore, MarylandAges 18 years+ - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age - NCT04712591Recruiting
Testing a recovery approach for people with severe brain injury
This study is testing a recovery strategy for adults who are in intensive care after a severe brain injury and are not able to follow commands. It may help doctors learn better ways to support recovery in this critical situation.
Miami, FloridaAges 18 years+ - NCT04728022Recruiting
Brain research apprenticeship in New York at Columbia
This program is an apprenticeship where students and mentors work with brain research at Columbia. If you’re invited to join, this trial mainly matches you to the program rather than testing a specific medicine.
New York, New YorkAges 15 years+ - NCT04735458Recruiting
Brain network study for Parkinson’s or essential tremor
This study looks at how “inhibitory control” brain networks work in people with Parkinson’s disease or essential tremor. If you are eligible for surgery and can do the study tasks, your results may help researchers better understand movement disorders and guide future treatments.
Birmingham, AlabamaAges 18 years+ - NCT04740580RecruitingEarly Phase 1
Test glutathione for brain inflammation in Alzheimer’s
This early-stage study tests whether taking glutathione can affect brain “inflammation” and metabolism in people with Alzheimer’s disease. You might benefit from a new treatment approach, while helping researchers understand what works best for early Alzheimer’s-related brain changes.
Houston, TexasAges 55–85 - NCT04751331RecruitingPhase 1/Phase 2
Study brain response to inflammation in depression
This early-stage study tests how your brain responds to an “inflammatory challenge” in people with major depressive disorder and in healthy volunteers. It may help researchers understand the immune-to-brain link in depression and guide future treatments.
Tulsa, OklahomaAges 18–65 - NCT04759326Recruiting
Hippotherapy after stroke to improve movement and function
This trial studies whether therapy using a horse (hippotherapy) can help adults who still have stroke-related physical difficulties more than 3 months after their stroke. It aims to improve daily function and movement when standard recovery has not been enough.
La CanourgueAges 18 years+ - NCT04770025RecruitingPhase 2
Brain stimulation with therapy for risky alcohol use
This study tests whether a non-invasive brain stimulation device can make standard psychotherapy work better for people who drink in a risky way. It’s designed for community participants who are not already in alcohol-use treatment.
Albuquerque, New MexicoAges 21–60 - NCT04783103Recruiting
Brain scan study of stimulation for depression in older adults
This is a pilot study that uses brain imaging to see how a brain “neuromodulation” approach may affect depression in people age 65 and older. You would be screened for depression severity, medication history, and safety limits, and then be asked to keep your depression medicines stable during the study.
Jette, Brussels CapitalAges 65 years+ - NCT04796714RecruitingPhase 4
Aspirin and clopidogrel after left heart appendix closure
This trial studies a “double anti-platelet” medicine plan (aspirin plus clopidogrel) after closing the left atrial appendage, a procedure used to reduce stroke risk in some heart rhythm conditions. It aims to find a safer, better medicine strategy for people who cannot take standard blood thinners.
PessacAges 18 years+ - NCT04817566Recruiting
Brain stimulation and training for thinking problems after breast cancer
This study tests whether brain stimulation plus cognitive training can improve thinking and memory problems in women after chemotherapy for breast cancer. It may help if you still feel “foggy” or have trouble concentrating months after treatment.
GreifswaldAges 18–65 - NCT04828798Recruiting
Directional versus standard brain stimulation for essential tremor
This study compares two ways of delivering deep brain stimulation (DBS) to treat essential tremor that affects both arms. It may help find a DBS approach that better controls tremor while reducing side effects.
Portland, OregonAges 18–80 - NCT04842812RecruitingPhase 1
Personalized immune cell therapy for advanced solid tumors
This Phase 1 study tests engineered immune cells (TILs/CAR-TILs) made from your tumor to treat advanced solid cancers that have not responded to standard treatments. It may help your immune system better recognize and attack the cancer, but it is mainly focused on safety and early results.
GuangzhouAges 18–85 - NCT04846140Recruiting
Non-invasive brain stimulation to help side vision in glaucoma
This study tests a non-invasive brain stimulation treatment to see if it can improve peripheral (side) vision in people with open-angle or normal-tension glaucoma. It targets people whose central vision is still relatively preserved but whose side vision has a measurable “gap” on vision testing.
Hong KongAges 18–80 - NCT04852744Recruiting
Brain scan study in teens with borderline and/or PTSD
This study uses brain imaging (MRI) to compare brain patterns in teens with borderline personality disorder and those with PTSD, as well as teens without these mental health diagnoses. It may help researchers understand what brain differences go along with these conditions and how they relate to each other.
CaenAges 13–18 - NCT04856501Recruiting
Parenting support for preterm toddlers’ brain and self-control
This study tests whether a responsive parenting program helps toddlers born early think, learn, and manage behavior more easily. It also checks whether families can complete toddler brain and behavior assessments (including brain scans).
Houston, TexasAges 1.3 years–2.5 years - NCT04911738Recruiting
Virtual reality glasses to improve balance after stroke
This trial studies whether virtual reality glasses training can improve balance and body alignment after a recent stroke. It will also compare how stroke participants with balance problems respond versus people without stroke.
GrenobleAges 18–80 - NCT04911452Recruiting
Calmer NICU care for very preterm babies
This study tests a calmer approach in the NICU to help very preterm babies grow and develop their brains. It may be helpful if your baby needs breathing support and is in the early weeks of life.
Vancouver, British ColumbiaAges 6 months–7 months - NCT04927156Recruiting
Check safety and use of Balt medical devices after treatment
This post-marketing study follows people after they receive Balt medical devices to make sure the devices are safe, work well, and are easy to use in real life. You may be considered if you can consent and your procedure matches their device-use rules.
AngersAges 2 years+ - NCT07698899RecruitingPhase 1
Study of a new treatment for childhood brain and CNS cancers
This trial tests a radioactive drug (177Lu-DTPA-Omburtamab) given directly into the fluid around the brain for children and teens with certain brain cancers or cancers that have spread to the central nervous system. It aims to see if this treatment is safe and effective for tumors that have come back or not responded to other therapies.
Basking Ridge, New JerseyAges 3–22
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.