Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05401929Recruiting
TMS to reduce cannabis use in heavy users
This study tests whether transcranial magnetic stimulation (TMS) can help heavy cannabis users cut down or stop. TMS uses a magnetic coil on the scalp to gently stimulate parts of the brain involved in cravings and habits.
Durham, North CarolinaAges 18–65 - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Birmingham, AlabamaAges 2 days–17 years - NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT07457567Recruiting
Social brain study in healthy adults
This study looks at how the brain works when we interact with others. It uses brain imaging to understand the 'social brain' in healthy adults.
New Haven, ConnecticutAges 18 years+ - NCT04943913RecruitingEarly Phase 1
TIL cell therapy for brain glioma after standard treatment fails
This early-stage study tests a treatment made from your tumor’s immune cells (TILs) to help shrink brain glioma. You may be considered if your glioma is back or has spread and standard options are no longer working (or don’t exist).
Suzhou, JiangsuAges 18–75 - NCT04958096Recruiting
Brain stimulation study for severe OCD symptoms
This trial studies a form of brain stimulation to help reduce severe obsessive-compulsive disorder (OCD) symptoms. It may be an option if your OCD has not improved despite several standard treatments and therapy.
San Francisco, CaliforniaAges 22–75 - NCT04965064RecruitingPhase 2
Neratinib plus capecitabine for HER2-negative breast cancer brain mets
This study tests whether neratinib plus capecitabine can slow or shrink breast cancer that has spread to the brain. It is for people whose cancer shows an “overactive HER2 signal” on a specific tumor test, even though their cancer is labeled HER2-negative.
Rochester, New YorkAges 18 years+ - NCT04981184Recruiting
Testing muscle signals to predict walking recovery after stroke
This study looks at surface muscle electrical signals (from electrodes on the skin) to understand and predict how well your balance and walking may improve after a first stroke. You might benefit by learning more about your recovery and by helping researchers find better ways to track progress.
KaunasAges 18–89 - NCT04982562Recruiting
7-tesla MRI for symptoms after a mild concussion
This study checks whether a stronger MRI scan (7-tesla) can help diagnose and better understand ongoing symptoms after a mild concussion. You would be scanned about 7 days after your injury to compare results with typical care.
PoitiersAges 20–72 - NCT04982965RecruitingEarly Phase 1
Study brain changes behind cannabis pain relief
This early study looks at how the brain may respond to cannabis to reduce long-lasting lower back pain. You may be asked to follow strict rules about cannabis, opioids, and safety checks (including MRI) to help researchers understand the brain mechanisms.
La Jolla, CaliforniaAges 21–65 - NCT04986683Recruiting
MRI study to reduce brain deficits after pediatric epilepsy surgery
This study uses special MRI pictures to better plan epilepsy surgery and help lower the chance of new brain problems after surgery. It includes children and teens with drug-resistant focal epilepsy who are having a two-stage surgery with brain surface electrodes.
Detroit, MichiganAges 3–19 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Birmingham, AlabamaAges 1–120 - NCT05004610RecruitingPhase 2
Hypertonic lactate treatment after cardiac arrest
This trial studies whether giving a specific IV fluid (hypertonic lactate) soon after resuscitation from cardiac arrest can improve recovery. It is for adults who remain in a deep unresponsive state after return of spontaneous circulation.
Brussels, BelgiumAges 18 years+ - NCT05011045Recruiting
Brain radiation study tracking thinking and memory changes
This study looks at how whole-brain radiation affects thinking, memory, and other brain function in people with blood cancers that involve the brain. It may help doctors understand what to expect and which supportive treatments or monitoring could be useful.
Houston, TexasAges 18 years+ - NCT05013736Recruiting
Study to test recovery in babies with brain injury
This study looks at how well babies recover after certain types of brain injuries that happen around birth, such as stroke, bleeding, or lack of oxygen. You might join if your baby fits the specific age range and has a confirmed injury on brain imaging.
Madison, WisconsinAges birth–2 years - NCT05014399Recruiting
Study memory changes during chemotherapy for colorectal cancer
This study looks at cognitive (thinking and memory) changes in people with colorectal cancer who start certain chemotherapy drugs. It aims to understand how treatment affects the brain and may guide better monitoring or support during care.
Fort Wayne, IndianaAges 18 years+ - NCT05017142Recruiting
Pediatric brain inflammation registry for Swiss patients
This study is a registry that collects health information from children and teens in Switzerland diagnosed with certain inflammatory brain and spinal cord conditions. It helps researchers understand these illnesses better over time and may guide future treatments.
Aarau, Canton of AargauAges Up to 36 years - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT05044208Recruiting
Test heart ultrasound and monitoring clues for atrial fibrillation
This study looks at heart ultrasound pictures and heart-rhythm recordings to predict who may develop atrial fibrillation (AF) after a stroke or TIA. If you qualify, your results may help doctors better spot people at higher risk earlier.
TullnAges 18 years+ - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80 - NCT05049057RecruitingPhase 2
Testing a nerve-blocking shot for recent mild TBI
This Phase 2 study tests a medication that blocks a pain signal (a CGRP receptor antibody) in people who recently had a mild traumatic brain injury (mTBI) and are also dealing with post-traumatic headache (PTH). The goal is to see if it can reduce symptoms and improve recovery after the injury.
Fort Bragg, North CarolinaAges 18–50 - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+ - NCT05066308RecruitingPhase 2
Cannabidiol to reduce inflammation in chronic low back pain
This Phase 2 study tests cannabidiol (CBD) to calm inflammation in the brain that may be linked to chronic low back pain. If you qualify, you’ll take study CBD and undergo brain imaging to see whether inflammation changes.
Boston, MassachusettsAges 18–75
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.