Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05360290Recruiting
Study checks cancer cells in breast tissue after surgery
This trial looks for circulating tumor cells—cancer cells that may travel in the blood—after standard breast cancer treatment, including chemotherapy before surgery and surgery itself. It may help doctors understand who might be at higher risk and tailor follow-up care.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06738654Recruiting
Robotic breast-conserving surgery through the armpit for early-stage breast cancer
This trial tests a new robotic technique for removing early-stage breast cancer through the armpit, leaving no scar on the chest. It may be an option for women who want to keep their breast shape and avoid visible scarring.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06726148RecruitingPhase 1/Phase 2
Study of ECI830 for advanced breast cancer and solid tumors
This trial is testing a new drug called ECI830, either alone or with another drug, for people with advanced breast cancer or other solid tumors that have not responded to standard treatments. It may be an option if you have HR+/HER2- breast cancer, small cell lung cancer, or a tumor with a specific gene change (CCNE1 amplification).
Los Angeles, CaliforniaAges 18–100 - NCT07623369RecruitingPhase 1
First-in-Human Study of HH160 for Advanced Solid Tumors
This is an early-stage trial testing a new drug called HH160 in patients with advanced cancer (solid tumors). Researchers want to find the right dose and learn how well it works and what side effects it causes.
Waratah, New South WalesAges 18–75 - NCT04503265RecruitingPhase 1/Phase 2
AMXI-5001 study for advanced cancers that won’t respond
This Phase 1/2 trial tests AMXI-5001 in people with advanced cancers that have progressed or stopped responding to standard treatments. It’s mainly designed to find the safest dose and see early signs the treatment might work.
Los Angeles, CaliforniaAges 18 years+ - NCT06533332RecruitingPhase 1
Testing ERX-315 for advanced solid tumors
This trial tests a new drug called ERX-315 for people with advanced solid tumors (like breast, ovarian, pancreatic, endometrial, or liver cancer) that have not responded to standard treatments. The goal is to see if the drug is safe and how well it works.
Ryde, New South WalesAges 18 years+ - NCT05835739Recruiting
Study of breast cancer prevention in BRCA1/2 mutation carriers
This is an observational study that looks at how different cancer prevention approaches affect women with harmful (deleterious) BRCA1 or BRCA2 mutations. It may help improve future prevention and follow-up plans for women at higher inherited risk.
Aviano, PordenoneAges 18 years+ - NCT06538896RecruitingPhase 2
Tislelizumab and nab-paclitaxel for advanced triple-negative breast cancer with bone spread
This trial tests a combination of two drugs, tislelizumab (an immunotherapy) and nab-paclitaxel (a chemotherapy), as the first treatment for advanced triple-negative breast cancer that has spread to the bones. It aims to see if this combination can help shrink or control the cancer.
Hangzhou, ZhejiangAges 18–70 - NCT07409298Enrolling by invitation
AI support for breast cancer patients on CDK4/6 inhibitors
This trial tests whether an AI-powered management program can improve mental health and daily habits for people with HR+/HER2- breast cancer who are taking CDK4/6 inhibitor pills at home. It is designed to help you feel supported and stay on track with your rehabilitation plan.
TianjinAges 18–80 - NCT06305962RecruitingEarly Phase 1
Radioactive drug for advanced PD-L1 positive solid tumors
This trial tests a radioactive medicine (177Lu-anti-PD-L1 sdAb) that delivers radiation to cancer cells with PD-L1 protein, which is found on some solid tumors. It is for people whose cancer has spread or come back after standard treatments.
Kingswood, New South WalesAges 18 years+ - NCT05296564RecruitingPhase 1/Phase 2
TCR cell therapy for NY-ESO-1 positive metastatic cancers
This study tests a customized immune-cell treatment made from your own T cells to attack cancers that have NY-ESO-1. It may help shrink tumors in people with metastatic or hard-to-treat cancer when other treatments have not worked.
JerusalemAges 18–70 - NCT06415266Recruiting
Sexual quality of life in breast cancer with onco-sexology support
This trial tests whether offering onco-sexology support proactively (right away) or on-request helps improve sexual quality of life for people finishing breast cancer treatment. If you've recently completed surgery, radiation, or chemotherapy (or started targeted therapies within the last 3 months), you may be able to join.
Saint-Herblain, Saint HerblainAges 18 years+ - NCT05190094RecruitingPhase 2
Test blood-based laser scan to guide first-line breast cancer treatment
This Phase 2 study uses a specialized laser test on a blood sample to predict how well palbociclib plus letrozole or anastrozole will work. It’s for certain postmenopausal women with HER2-negative, hormone-receptor positive, advanced (stage IIIb/IV) breast cancer.
BlidaAges 18 years+ - NCT06884852Recruiting
Preventing pain after mastectomy: nerve block vs. epidural
This study compares two methods to prevent long-term pain after breast cancer surgery: a nerve block using ultrasound guidance or an epidural. The goal is to see which helps women feel less pain months after their mastectomy.
CairoAges 18–65 - NCT07743190RecruitingPhase 2
Lighter chemo for early-stage triple-negative breast cancer with high immune cells
This trial tests a less intense chemotherapy regimen (without one of the standard drugs) combined with immunotherapy for people with early-stage triple-negative breast cancer whose tumors have a high level of immune cells (TILs). The goal is to see if this approach is effective while reducing side effects.
Syracuse, New YorkAges 18 years+ - NCT04019678Recruiting
Breast cancer study after chemotherapy with small underarm node spread
This study looks at whether it’s safe and effective to avoid removing many underarm lymph nodes in some people who, after chemotherapy, still seem to have only tiny (“micro”) cancer deposits in the sentinel lymph node. It may help reduce treatment side effects while keeping cancer control.
Rozzano, MIAges 18–75 - NCT04137653RecruitingPhase 3
New pre-surgery drug choice for triple-negative breast cancer
This trial tests which chemotherapy drug works better before surgery (neoadjuvant therapy) for triple-negative breast cancer that has spread to underarm lymph nodes. It compares two forms of paclitaxel given by random assignment to see which option may shrink the tumor more effectively and improve outcomes.
Shenyang, LiaoningAges 18–70 - NCT04817540RecruitingPhase 2
Testing anti-HER2 treatment for HER2-enriched early breast cancer
This trial tests an anti-HER2 medicine in people whose breast cancer is classified as “HER2-enriched” using a special lab test (PAM50). It aims to see whether this treatment can help prevent or control cancer that cannot be fully removed by surgery.
SeoulAges 19 years+ - NCT07629206Recruiting
Freezing therapy for small, early-stage breast cancer
This study tests whether freezing a small breast tumor (cryoablation) is a safe and effective treatment option for older adults with early-stage, hormone-receptor-positive breast cancer. Instead of surgery, the goal is to destroy the tumor by freezing it in place.
Glendale, CaliforniaAges 70 years+ - NCT06193525RecruitingPhase 2
Talazoparib for advanced breast cancer with a DNA repair defect
This trial tests a drug called talazoparib (a PARP inhibitor) for advanced breast cancer that has a specific DNA repair defect (HRD) or a BRCA mutation. The goal is to see if the drug works better when the patient's tumor is tested for this defect just before treatment.
Leiden, South HollandAges 18 years+ - NCT05838066RecruitingPhase 3
KN026 plus HB1801 for HER2-positive advanced breast cancer
This Phase 3 study tests whether taking KN026 with HB1801 as first treatment works better and is safe for people with HER2-positive breast cancer that has come back or spread. It may help by improving tumor response and delaying progression compared with the study’s treatment plan.
Beijing, chaoyangAges 18 years+ - NCT06595147Recruiting
Exercise for heart health in breast cancer survivors
This study tests if a 12-week exercise program improves heart health in women over 60 who have finished treatment for early-stage breast cancer. You will be placed in either an aerobic exercise group or a stretching group to see which helps your heart more.
Edmonton, AlbertaAges 60 years+ - NCT05879926RecruitingPhase 3
Testing chemo after hormone therapy in premenopausal early breast cancer
This Phase 3 trial checks whether adding chemotherapy after standard hormone-blocking treatment works better for some premenopausal women with early-stage, ER-positive, HER2-negative breast cancer. It targets patients with limited lymph node spread and a lower-to-intermediate tumor “recurrence” risk score.
Birmingham, AlabamaAges 18–60 - NCT05621837Recruiting
Biomarker study to guide treatment for several advanced cancers
This study measures how strongly your immune system is being suppressed and uses that information to help personalize cancer treatment. It mainly looks at people with certain advanced cancers and needs tumor tissue and follow-up to check possible immune-related markers.
MilanAges 18–90
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,417 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.