Clinical trials
Breast Reconstruction clinical trials
Below are recruiting breast reconstruction clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05975372Recruiting
Smart breast expander device for two-stage breast reconstruction
This study tests a new “smart” expander device used during two-step breast reconstruction or breast augmentation. It may help doctors improve how tissue expanders are managed before a final implant is placed.
Palo Alto, CaliforniaAges 18–65 - NCT06556654Recruiting
Tissue reinforcement for breast reconstruction study (REDEFINE)
This study tests a new tissue reinforcement device (like a mesh) used during two-stage implant-based breast reconstruction after a mastectomy. It is designed for women having their first reconstruction and may help support the implant and improve healing.
Scottsdale, ArizonaAges 22 years+ - NCT06995118Recruiting
New technique for nipple-sparing mastectomy with immediate implant reconstruction
This trial tests a special tool (HUAXI Hole 1) for a type of breast cancer surgery that removes breast tissue while saving the nipple, followed by placing an implant right away. It may be an option for women with early-stage breast cancer or those who choose preventive mastectomy.
Fuzhou, FujianAges 18–70 - NCT06981481Recruiting
Breast expander safety study for reconstruction
This study is tracking how a silicone breast expander (a temporary balloon placed under the skin to stretch it) and a permanent silicone breast implant perform over time in women who need breast reconstruction. It aims to make sure the Silimed-brand expander and implant are safe and work well.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07037537Recruiting
Nipple-sparing mastectomy with immediate reconstruction (fat and implant)
This trial tests a breast cancer surgery that removes the breast but saves the nipple, followed by immediate reconstruction with an implant and some of your own fat. It's for women with early-stage cancer that hasn't spread to lymph nodes.
Zhengzhou, HenanAges 18–70 - NCT07264790RecruitingPhase 1
Minoxidil for Better Blood Flow in Breast Reconstruction
This trial tests whether applying minoxidil (a hair growth medication) to breast tissue during surgery can improve blood flow to the reconstructed breast. It is for women who are having both breasts removed to prevent cancer and have reconstruction on the same day.
Durham, North CarolinaAges 18 years+ - NCT05987475Recruiting
10-year study of breast implants for reconstruction or cosmetic surgery
This study follows women who receive Euromi Biosciences silicone gel breast implants during either breast reconstruction after mastectomy or cosmetic breast surgery. It aims to see how the implants perform over 10 years.
NancyAges 18–60 - NCT07602374Recruiting
Written vs. Video Education for Breast Reconstruction Surgery
This study compares two ways of learning about breast reconstruction options after mastectomy—reading written materials versus watching videos. Researchers want to see which method helps patients make better-informed decisions and feel more confident about their choice.
San Francisco, CaliforniaAges 18 years+ - NCT05190978Recruiting
Test mesh use for breast reconstruction above the muscle
This study tests whether using surgical mesh can be done safely and works well in breast reconstruction done right away, in front of the chest muscle (pre-pectoral) using tissue expanders. It may help improve how the reconstructed area holds up, but you’d need to meet specific surgical and health requirements.
Los Angeles, CaliforniaAges 22–75 - NCT05490433Recruiting
Robot-assisted versus open nipple-sparing mastectomy with reconstruction
This trial compares two surgical approaches to remove the breast using a nipple-sparing mastectomy and do immediate breast reconstruction—either robot-assisted or open surgery. It aims to see how well each method works and how patients do afterward.
ChangwonAges 19–70 - NCT06195865Recruiting
Comparing body-tissue vs. implant breast reconstruction
This trial compares two types of breast reconstruction after mastectomy: using your own tissue (DIEP flap) versus using an implant. It aims to see which gives better results.
GothenburgAges 18 years+ - NCT06523452Recruiting
Laser imaging during breast reconstruction surgery
This trial uses a special camera to monitor blood flow during breast reconstruction surgery. It may help doctors ensure the tissue stays healthy during the procedure.
Exeter, DevonAges 18 years+ - NCT07044583Recruiting
Safe Opioid Use Video Education for Breast Reconstruction
This trial tests a video education program to help women safely use opioids after breast reconstruction surgery. It is for patients who have had a mastectomy and are getting a breast rebuilt using their own tissue.
Salt Lake City, UtahAges 18 years+ - NCT07008339Recruiting
Nipple reconstruction using hyaluronic acid injections
This study tests if injecting a gel-like substance (hyaluronic acid) can improve nipple reconstruction in women who have had mastectomies. It aims to see if this method works better than or alongside tattoos for rebuilding the nipple-areola area.
Badalona, BarcelonaAges 18 years+ - NCT06258863Enrolling by invitation
Comparing incision types in breast reconstruction after mastectomy
This study compares different types of surgical cuts (incisions) used during breast reconstruction after mastectomy. It looks at which incision gives the best cosmetic result and causes the fewest problems. Researchers want to find out which technique is best for you.
Wuhan, Hongshan DistrictAges 18 years+ - NCT07140198Recruiting
Hyperbaric oxygen therapy for better fat graft survival after breast radiation
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help transplanted fat tissue survive better in women who have had radiation for breast cancer. It is for women planning a follow-up fat grafting procedure after breast reconstruction.
Geneva, Canton of GenevaAges 18 years+ - NCT07335354Recruiting
Decision tool for breast reconstruction after mastectomy
This study is testing a decision tool to help people who are thinking about breast reconstruction surgery after a mastectomy. The tool is designed to help you and your doctor make a more informed choice.
Basking Ridge, New JerseyAges 18 years+ - NCT07234461Recruiting
Sexual well-being after mastectomy and reconstruction
This study looks at how mastectomy and breast reconstruction affect a woman's sexual well-being. If you are having a mastectomy for breast cancer or a preventive mastectomy because you are at high risk, you may be able to join.
Bari, ItalyAges 18 years+ - NCT06919042Recruiting
Shockwave therapy for breast reconstruction scar tissue
This trial tests if a special shockwave treatment can soften firm scar tissue that sometimes forms after breast reconstruction surgery. If you've had plastic surgery and have firm, tight areas under your skin, this study might be able to help.
Chicago, IllinoisAges 18 years+ - NCT07718425Recruiting
Endoscopic mastectomy surgery study
This study tests a new, less invasive surgery called endoscopic mastectomy for women who need breast removal. It aims to see how well the surgery works, how the breast looks and feels afterward, and whether nipple sensation is preserved.
Ponderano, BIAges 18–75 - NCT06428682RecruitingPhase 4
TXA for Bleeding in Breast Reconstruction with Free Flaps
This trial tests whether a medicine called TXA (tranexamic acid) can help reduce bleeding during breast reconstruction using your own abdominal tissue. It's for women having this surgery at UVA Medical Center.
Charlottesville, VirginiaAges 18 years+ - NCT07178886Recruiting
Breast Reconstruction and Radiation Therapy Study
This study looks at how breast reconstruction (rebuilding the breast shape) affects women who have had a mastectomy and need radiation therapy. It aims to see if reconstruction can be done safely and with good results when followed by radiation.
RotterdamAges 18 years+ - NCT05216900Recruiting
Breast reconstruction with radiation given before surgery
This study looks at how breast reconstruction works when radiation is planned around the time of surgery, including in some people before surgery depending on lymph node results. It may help improve safety and outcomes for people needing mastectomy and chest/radiation therapy.
Bilthoven, UtrechtAges 18–75 - NCT05692674RecruitingPhase 2
Proton radiation after breast surgery with implant reconstruction
This trial studies a type of radiation made with proton beams given after mastectomy and implant reconstruction to lower breast cancer coming back. It’s for people who need additional (adjuvant) radiation and have not had prior radiation to the chest or breast.
Shanghai, Shanghai MunicipalityAges 18–80
Hear when a new Breast Reconstruction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for breast reconstruction?
- Yes. Clin2 currently lists 110 recruiting breast reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Breast Reconstruction After Mastectomy
- Implant Based Breast Reconstruction
- Mastectomy and Breast Reconstruction
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Breast Reconstruction Surgery
- DIEP Flap Breast Reconstruction
- Triple Negative Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.