Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,627 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05587777Recruiting
Tracking chronic conditions during standard breast cancer treatment
This study monitors health problems that can happen over time in people with breast cancer while they receive usual treatments like hormone therapy, chemotherapy, and/or radiation. It may help researchers understand which extra symptoms or complications show up and when, to improve care and follow-up.
StavangerAges 19–80 - NCT04263298RecruitingPhase 3
Fulvestrant or capecitabine after chemo for metastatic breast cancer
This Phase 3 trial compares two medicines—fulvestrant versus capecitabine—as “maintenance” treatment after your first chemo helps control metastatic breast cancer. It aims to see which one helps people live longer with better disease control.
Guangzhou, GuangdongAges 18–75 - NCT04904757Recruiting
CESM contrast mammogram screening for dense breasts
This trial tests a newer kind of breast screening scan that uses a special dye (contrast) to better show breast tissue. It may help people with very dense breasts get clearer screening images.
Charlottesville, VirginiaAges 40–69 - NCT04472845Recruiting
Shorter or longer breast radiation after surgery for high-risk cancer
This trial compares two schedules of radiation after breast surgery in people with high-risk, node-positive breast cancer. The goal is to see whether giving radiation in 1 week or 2 weeks works well and is safe after standard treatments.
ChandigarhAges 18 years+ - NCT05627960RecruitingPhase 1
Testing an antibody drug for advanced solid cancers
This Phase 1 study tests AG01, an antibody that targets a cancer protein called GP88, in people with advanced solid tumors. The goal is to find safe doses and learn whether it can help certain cancers.
Baltimore, MarylandAges 18 years+ - NCT05692674RecruitingPhase 2
Proton radiation after breast surgery with implant reconstruction
This trial studies a type of radiation made with proton beams given after mastectomy and implant reconstruction to lower breast cancer coming back. It’s for people who need additional (adjuvant) radiation and have not had prior radiation to the chest or breast.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05731258Recruiting
Watch how liposomal doxorubicin is used after breast cancer
This is an observational study that follows people receiving add-on (adjuvant) chemotherapy after primary breast cancer. It aims to understand treatment patterns and outcomes for patients healthy enough to receive liposomal doxorubicin and who have no major complications.
Hangzhou, ZhejiangAges 18–75 - NCT05753657RecruitingEarly Phase 1
Testing insulin and blood sugar monitoring with pioglitazone
This early study tests whether adding pioglitazone, along with close blood-sugar (glucose/insulin) monitoring, can help control high insulin and high blood sugar in people starting alpelisib for metastatic breast cancer. It may help reduce blood-sugar side effects from alpelisib.
HaifaAges 18–85 - NCT05762900RecruitingPhase 2
Shorter breast radiation after surgery for low-risk breast cancer
This Phase 2 trial tests a shorter, focused radiation treatment after breast surgery, either alone or with an extra targeted boost. It’s for people with low-risk breast cancer and no spread to distant organs, aiming to keep results while reducing treatment time and side effects.
BeijingAges 35 years+ - NCT05761470RecruitingPhase 2
Test before-surgery cancer treatment for breast tumors with DNA repair gene changes
This trial tests a combination of medications given before surgery (neoadjuvant therapy) for early breast cancer. It is designed for tumors with certain “DNA repair” gene mutations and aims to improve treatment results while shrinking or controlling the cancer.
Guangzhou, GuangdongAges 18–75 - NCT04483804Recruiting
Using computer image features to study breast cancer
This study looks at breast cancer images to see whether computer-extracted patterns (“radiomics”) can help improve understanding of the disease. You may be included if your breast cancer diagnosis is confirmed and your medical records are complete.
Hanzhou, ZhejiangAges 18–80 - NCT05638594RecruitingPhase 2
Neoadjuvant drug study for hormone- and HER2-positive breast cancer
This trial compares two combination treatment plans given before breast surgery (neoadjuvant therapy) for ER-positive and HER2-positive stage II–III breast cancer. It aims to see which plan works better to shrink the tumor and improve outcomes.
Shenyang, LiaoningAges 18–75 - NCT05804916RecruitingPhase 2/Phase 3
Tracking-guided radiation for left breast after surgery
This trial tests a radiation planning and monitoring approach that uses surface tracking and breathing control to deliver large-area radiation more accurately for left breast cancer. It may help improve how consistently treatment is delivered while accounting for chest movement.
Beijing, Beijing MunicipalityAges 18–70 - NCT05212454RecruitingPhase 3
Capecitabine added after surgery for high-risk ER-positive breast cancer
This Phase 3 study tests whether adding capecitabine (a chemotherapy pill) after breast cancer surgery can lower the chance the cancer comes back. It targets people with hormone-receptor–positive and HER2-negative breast cancer who are considered “high risk.”
Hanzhou, ZhejiangAges 18–70 - NCT04800393Recruiting
Breast surgery anesthesia and its effects on immunity and survival
This study compares two ways of giving anesthesia during breast cancer surgery to see how they affect the immune system and outcomes after surgery. It may help identify which anesthesia approach is better for people like you having early-stage, operable breast cancer surgery.
MoscowAges 45–74 - NCT05835739Recruiting
Study of breast cancer prevention in BRCA1/2 mutation carriers
This is an observational study that looks at how different cancer prevention approaches affect women with harmful (deleterious) BRCA1 or BRCA2 mutations. It may help improve future prevention and follow-up plans for women at higher inherited risk.
Aviano, PordenoneAges 18 years+ - NCT05834764RecruitingPhase 2
Pyrotinib for high-risk HER2-positive early breast cancer
This Phase 2 trial tests pyrotinib, a HER2-targeted cancer medicine, in people with high-risk, HER2-positive breast cancer after surgery. It aims to lower the chance the cancer comes back, especially when standard treatment did not fully clear the tumor.
Nanjing, JiangsuAges 18–75 - NCT05851014RecruitingPhase 3
GB491 plus letrozole for HR+ HER2- advanced breast cancer
This Phase 3 study tests whether GB491 used together with letrozole works better for hormone receptor–positive and HER2-negative advanced breast cancer. You may be eligible if you have not had certain prior cancer treatments and your health tests are within safe limits.
Bengbu, AnhuiAges 18–75 - NCT05795335Recruiting
Testing CDK4/6 medicines for advanced hormone-positive breast cancer
This trial studies how CDK4/6 medicines fit into treatment for people with advanced hormone receptor–positive breast cancer that cannot be cured with surgery or radiation. It may help doctors understand the best way to use these medicines for disease that has returned or spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05447702RecruitingPhase 2
Testes pre-surgery treatment for triple-negative breast cancer
This trial studies giving camrelizumab plus apatinib and chemotherapy before surgery for triple-negative breast cancer. The goal is to shrink the tumor and improve outcomes by testing a combination of immune and targeted medicines along with chemotherapy.
Chengdu, SichuanAges 18–75 - NCT05890287Recruiting
Chidamide plus hormone therapy after chemotherapy for breast cancer
This trial studies chidamide added to standard hormone (endocrine) therapy to help prevent breast cancer from coming back after initial chemotherapy. It may help by keeping cancer under control for longer in people with HR-positive, HER2-negative breast cancer who respond to first-line treatment.
TianjinAges 18–75 - NCT04020575RecruitingPhase 1
CAR T cells made from your blood for advanced breast cancer
This Phase 1 trial tests CAR T cells made from your own immune cells to target advanced breast cancer. The cells are designed to recognize a specific cancer marker (called MUC1*), with the goal of shrinking tumors or keeping them under control.
Duarte, CaliforniaAges 18 years+ - NCT05058183Recruiting
Testing shorter chemotherapy for early HER2 or triple‑negative breast cancer
This study looks at whether some people with stage 1 HER2-positive or “triple-negative” breast cancer may safely need less (de-escalated) chemotherapy after surgery. The goal is to keep the cancer risk low while reducing treatment intensity, using special blood testing over time.
LondonAges 18 years+ - NCT05904964RecruitingPhase 3
Targeted drug for hormone-positive, HER2-low metastatic breast cancer
This Phase 3 trial tests disitamab vedotin (a targeted drug) in people with hormone receptor–positive, HER2-low metastatic breast cancer that can’t be cured with surgery or radiation. It aims to see whether the drug can control the cancer better than current standard care.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,627 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.