Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04235764Recruiting
Testing a new bladder-tumor surgery tool for removed tissue
This trial studies a redesigned surgical instrument used during bladder tumor removal, to see if it can improve how the removed tissue samples are collected. It may help future patients by supporting better study of bladder tissue during cancer care.
Bethesda, MarylandAges 18–120 - NCT04243720Recruiting
Study of immune resistance after immunotherapy
This trial studies why some solid cancers stop responding to immune-based drugs (like anti–PD-1/PD-L1) and what can be done next. You may be eligible if your cancer has progressed after immunotherapy and you can safely undergo a tumor needle biopsy.
Toronto, OntarioAges 18 years+ - NCT04245683Recruiting
Testing non-surgical treatment for newly diagnosed rectal cancer
This study looks at whether it’s practical and safe to treat certain rectal cancers without surgery. You may be offered non-surgical (“neoadjuvant”) treatment and close follow-up to see how well it works in a rural setting.
Cooperstown, New YorkAges 18 years+ - NCT04249154RecruitingPhase 2
After prostate surgery, test radiation plus hormone shots
This trial studies whether giving a shorter-course radiation plan after prostate surgery, along with hormone shots (LHRH), can improve outcomes for people with higher-risk prostate cancer. You may be eligible if your PSA (a blood marker) is either still low but high-risk by pathology, or it has started to rise again after surgery.
Montreal, QuebecAges 18 years+ - NCT04261244RecruitingPhase 3
Neoadjuvant radiation study for one-sided breast cancer
This Phase 3 study tests a specific plan that combines chemotherapy (and sometimes targeted medicines) with radiation before surgery for one breast. It may help shrink breast cancer and improve treatment timing, based on how well tumors respond.
AhausAges 18 years+ - NCT04263298RecruitingPhase 3
Fulvestrant or capecitabine after chemo for metastatic breast cancer
This Phase 3 trial compares two medicines—fulvestrant versus capecitabine—as “maintenance” treatment after your first chemo helps control metastatic breast cancer. It aims to see which one helps people live longer with better disease control.
Guangzhou, GuangdongAges 18–75 - NCT04265937Recruiting
Genetic screening for breast cancer risk in Chinese communities
This study checks certain genes using blood or mouth (oral) samples in people who already have breast cancer. The goal is to better understand genetic risk in Chinese communities and help guide future care.
Shanghai, Shanghai MunicipalityAges Any age - NCT04271579Recruiting
Surgery for early prostate cancer spread seen on PSMA PET
This trial studies whether operating on a small, one-sided (unilateral) area of prostate cancer spread in the pelvic lymph nodes—found on a PSMA PET scan—can help control recurrence. It’s meant for people whose PSA is still low and whose spread appears limited on the scan.
HamburgAges 18–75 - NCT04275557Recruiting
Using scan and blood data to judge pancreatic cyst risk
This study looks at how medical images and lab samples can predict which pancreatic cysts or tumors are more likely to be dangerous. If you are being evaluated for a pancreatic problem and haven’t started pancreas treatment, your scans and samples may help researchers improve risk prediction.
Lakewood Rch, FloridaAges 18 years+ - NCT04278222RecruitingPhase 2
Anlotinib plus immunotherapy for advanced stomach cancer
This Phase 2 study tests whether combining two medicines—anlotinib and toripalimab—can work well as first treatment for advanced (stage IV) stomach cancer. It’s meant for people who have an adequate overall health status and certain blood/organ function levels.
ShanghaiAges 18 years+ - NCT04280822RecruitingPhase 3
Immunotherapy plus chemo versus chemo alone before surgery
This Phase 3 trial tests whether adding immunotherapy to chemotherapy before surgery works better than chemotherapy alone for resectable esophageal cancer. The goal is to improve outcomes after tumor shrinkage before the operation.
Zhengzhou, HenanAges 18–75 - NCT04282122Recruiting
Personalized radiation plan for older women with early breast cancer
This trial uses individual measures of how sensitive your body’s tissues are to radiation to guide after-surgery breast radiation treatment. It aims to keep treatment safe and effective while tailoring the plan to each person.
Montpellier, OccAges 65 years+ - NCT04284189Recruiting
Aftercare study for survivors of childhood cancer in Switzerland
This study looks at follow-up care needs for people who survived childhood cancer, especially those in the later teen/adult years. You may be invited to complete questionnaires so the study team can understand and improve long-term aftercare.
AarauAges 16 years+ - NCT04287088Recruiting
MRI plus shared decisions to help diagnose prostate cancer
This study looks at using a special prostate MRI (bpMRI) along with a risk-based shared decision process to guide diagnosis. It may help patients and clinicians decide on next steps using MRI results and individual risk.
JyväskyläAges 18 years+ - NCT04289935Recruiting
Vacuum biopsy before surgery to check treatment response
This trial studies a special vacuum-assisted biopsy taken just before breast surgery to see how well pre-surgery (neoadjuvant) chemotherapy worked. It may help doctors understand whether patients truly had a complete or near-complete response on scans, which can guide next steps.
SalzburgAges 18 years+ - NCT04295863RecruitingPhase 1
Test different dosing schedules for two immunotherapy drugs
This early trial compares how often two immune system medicines—nivolumab and pembrolizumab—are given for advanced or metastatic cancers. It aims to see which dosing interval is workable and safe for people needing treatment.
Chicago, IllinoisAges 18 years+ - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT04297605RecruitingPhase 1
Pembrolizumab plus chemotherapy for advanced lung cancer
This Phase 1 study tests pembrolizumab (an immunotherapy) given together with a chemotherapy drug to treat non-small cell lung cancer that is locally advanced or has spread. It’s aimed at people who can handle treatment with an ECOG performance status of 2, including some with certain types of brain metastases.
Rochester, New YorkAges 18 years+ - NCT04300062Recruiting
Rebiopsy of lung cancer after treatment no longer works
This trial studies patients with lung cancer whose disease has continued to grow despite immunotherapy. It involves taking a new tissue sample (a rebiopsy) to help doctors understand what changed during treatment and guide next steps.
Boulogne-BillancourtAges 18 years+ - NCT04302025RecruitingPhase 2
Testing targeted and immunotherapy before lung cancer surgery
This trial studies whether giving different cancer medicines before (and sometimes after) surgery improves outcomes for people with early-stage, operable lung cancer that has certain tumor markers. It may help by trying to shrink or control the cancer early and lower the chance it comes back.
Duarte, CaliforniaAges 18 years+ - NCT04303988RecruitingPhase 2
Trial for brain metastases from triple-negative breast cancer
This Phase 2 study tests a treatment for people with triple-negative breast cancer that has spread to the brain. It’s designed for situations where the cancer can’t be safely cured with surgery or focused radiation.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT04322617RecruitingPhase 2/Phase 3
Anlotinib plus immunotherapy for lung cancer after first treatment
This trial studies an oral targeted medicine (anlotinib) combined with an immunotherapy (checkpoint inhibitor) for lung cancer that did not respond to first-line chemo-immunotherapy. It may help shrink tumors and improve disease control after standard treatment has failed.
Changsha, HunanAges 18 years+ - NCT04322890RecruitingPhase 2
Study for advanced lung cancer with gene mutations
This Phase 2 trial studies treatment strategies for people with stage IV non-small cell lung cancer (NSCLC) who have certain cancer gene mutations (like EGFR, ALK, or ROS1). It aims to see how different treatments affect survival and tumor response.
Changsha, HunanAges 18 years+ - NCT04330521Recruiting
Cancer patients share experiences during the COVID-19 outbreak
This study asks adult cancer patients to complete a survey and talk in an interview about how COVID-19 affected their care and daily life. Your answers may help researchers understand what challenges cancer patients faced during the pandemic.
Stanford, CaliforniaAges 18–99
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.