Clinical trials · Minnesota
Cancer clinical trials in Minnesota
We’re tracking 552 recruiting cancer studies with a site in Minnesota — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT04294927Recruiting
Tube removal first, then ovaries later for high-risk women
This study looks at whether removing the fallopian tubes first, and the ovaries later, is safe for women with certain inherited gene mutations that raise ovarian cancer risk. It may help you understand a prevention approach when you’re considered high risk and have finished having children.
Rochester, MinnesotaAges 25–50 - NCT04118660Recruiting
Thoracic specimen registry for adults with chest conditions
This study is a “specimen registry,” meaning it collects and stores samples from adults with chest (thoracic) diseases. It may help researchers better understand lung and chest conditions and improve future testing or treatments.
Rochester, MinnesotaAges 18 years+ - NCT04239573Recruiting
Compare pancreatic cyst checkup programs and test markers
This study compares different ways to monitor pancreatic cysts and also measures blood or other test markers to see which approach is more helpful. It may help patients by finding the safest, most effective way to track certain cysts that could otherwise be hard to manage.
Worthington, MinnesotaAges 50–75 - NCT04166409RecruitingPhase 3
Selumetinib versus chemo for low-grade brain tumor in children
This trial studies whether the targeted drug selumetinib works better than standard chemotherapy (carboplatin and vincristine) for children and young adults with a specific type of low-grade glioma (grade 1 or 2). It may help shrink tumors and slow growth while comparing side effects between the two treatment approaches.
Minneapolis, MinnesotaAges 2–21 - NCT04251052Recruiting
Compare two surgeries to lower ovarian cancer risk in BRCA1 carriers
This study compares two risk-reducing surgery plans for people with a BRCA1 genetic change to see which approach helps lower ovarian cancer risk. You may be asked to have the study procedure sooner or later depending on your chosen plan.
Coon Rapids, MinnesotaAges 35–50 - NCT04031677RecruitingPhase 3
Surgery with or without chemotherapy for high-risk retroperitoneal sarcoma
This trial studies whether adding chemotherapy before surgery helps people with high-risk retroperitoneal (abdominal-area) leiomyosarcoma or liposarcoma. The goal is to improve outcomes while comparing surgery alone versus surgery plus neoadjuvant chemotherapy.
Bemidji, MinnesotaAges 18 years+ - NCT03937635RecruitingPhase 3
Lenalidomide and dexamethasone, with or without daratumumab
This phase 3 trial studies whether lenalidomide plus dexamethasone can prevent or delay progression of “high-risk smoldering” multiple myeloma, and whether adding daratumumab improves outcomes. It’s meant for people who are not yet showing symptoms, but whose lab and scan results suggest higher risk.
Fergus Falls, MinnesotaAges 18 years+ - NCT03899155RecruitingPhase 2
Study for continuing or restarting cancer treatment that worked before
This trial lets people who were already in a related “parent” study either keep taking treatment or restart it after it had stopped working for a while. It’s meant for people who previously had a meaningful response and may still benefit from continued treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT03942328RecruitingPhase 1/Phase 2
Immune cell vaccine plus checkpoint treatment after liver radiation
This trial tests a combination of a personalized immune cell treatment (made from your own cells) and a pneumococcal vaccine along with an “immune checkpoint” drug after high-dose radiation for certain unresectable liver cancers. The goal is to help your immune system better attack the cancer and to see how safe and effective this approach is.
Rochester, MinnesotaAges 18 years+ - NCT03739814RecruitingPhase 2
Test inotuzumab, blinatumomab, and possibly ponatinib for CD22 ALL
This Phase 2 study tests a combination of medicines (inotuzumab ozogamicin and blinatumomab), with or without ponatinib, for people with CD22-positive B-cell acute lymphoblastic leukemia (ALL). It aims to improve remission and control leukemia cells, including in the bone marrow.
Rochester, MinnesotaAges 18 years+ - NCT03789721Recruiting
ALD registry study for patients and families in the U.S.
This study builds a national registry to better understand adrenoleukodystrophy (ALD) in patients and families. You may help researchers learn how ALD affects people over time and improve future care.
Minneapolis, MinnesotaAges Any age - NCT03550391RecruitingPhase 3
Surgery-like brain radiation vs avoiding the memory center
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
Rochester, MinnesotaAges 18 years+ - NCT03579875RecruitingPhase 2
Testing an inherited bone marrow transplant approach for rare blood disorders
This Phase 2 study tests a special “T-cell depleted” transplant plan for people with inherited bone marrow failure disorders (Fanconi anemia or T-Beta-thalassemia—or “TBD”). It may help restore healthy blood production while lowering the chance of certain transplant complications.
Minneapolis, MinnesotaAges Up to 65 years - NCT03445585Recruiting
Biobank study for primary sclerosing and primary biliary cholangitis
This study collects and stores samples from people with PSC (primary sclerosing cholangitis), PBC (primary biliary cholangitis), and some related liver conditions. Researchers use these samples to better understand these diseases and support future research.
Rochester, MinnesotaAges 18–85 - NCT03314974RecruitingPhase 2
Stem cell transplant study for blood cancers
This Phase 2 study tests a strong (myeloablative) stem cell transplant using donor stem cells (allogeneic transplant) for certain blood and bone marrow cancers. The goal is to see how well this approach works and whether it can improve outcomes for people who need transplant-level treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT03432936Enrolling by invitation
Uses Philips iSuite during MRI-guided procedures
This study tests a software tool (Philips iSuite) to help doctors during MRI-guided, minimally invasive procedures. You may be able to participate if you’re already scheduled for this type of procedure, unless you are pregnant.
Rochester, MinnesotaAges 18–90 - NCT02984761Recruiting
Surgery vs focused radiation for early lung cancer
This trial compares two ways to treat early-stage lung cancer: surgery or a precise type of radiation called stereotactic radiotherapy. It aims to find out which approach works best for people whose cancer is small and has not spread.
Minneapolis, MinnesotaAges 18 years+ - NCT02958462Recruiting
Clinic study for early blood or bone marrow warning signs
This study follows people who may have early, unclear blood count problems or certain genetic/immune patterns that can later lead to bone marrow failure or blood cancers. It may help doctors better understand risks over time and guide earlier care.
Rochester, MinnesotaAges 18 years+ - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Minneapolis, MinnesotaAges Up to 25 years - NCT02579967RecruitingPhase 2
Stem cell transplant for primary immune system disorders
This study tests whether an allogeneic stem cell (bone marrow) transplant can correct an inherited immune problem in people with severe primary immunodeficiencies. It may help reduce life-threatening infections and improve quality of life, depending on your overall health and donor match.
Minneapolis, MinnesotaAges 4–75 - NCT02560883Recruiting
Hairy cell leukemia patient data registry
This registry collects information about people with classic and variant hairy cell leukemia. It helps doctors learn from real-world patient data and may improve future care.
Rochester, MinnesotaAges 18 years+ - NCT01451502Recruiting
Study uses donor cord blood to restore blood cell production
This study tests giving you donated umbilical cord blood through an IV to help your body rebuild blood-forming cells after chemotherapy. It may help people who need a stem-cell “reset” using a specific type of cord blood unit that meets strict matching and safety rules.
Minneapolis, MinnesotaAges Any age - NCT02081755Enrolling by invitationPhase 4
Everolimus after liver transplant to lower liver cancer return
This trial studies whether everolimus, a transplant medicine, can safely reduce the chance that liver cancer comes back after liver transplant. It compares how well the treatment works while carefully monitoring side effects and safety.
Rochester, MinnesotaAges 18 years+ - NCT01666080Recruiting
Second bone marrow transplant with gentler chemotherapy
This trial studies a “reduced intensity” second transplant using donated blood-forming cells, for people whose first transplant did not fully and reliably restart blood production. It aims to improve donor blood cell growth while using a less harsh conditioning approach.
Minneapolis, MinnesotaAges Up to 55 years
Cancer trials by city in Minnesota
Where these studies are running in Minnesota
Institutions with a site for the recruiting cancer studies listed above.
- Mayo Clinic · 16 studies
- Masonic Cancer Center · 5 studies
- Regions Hospital · 3 studies
- University of Minnesota/Masonic Cancer Center · 3 studies
- Abbott-Northwestern Hospital · 2 studies
- Cambridge Medical Center · 2 studies
- Children's Hospitals and Clinics of Minnesota - Minneapolis · 2 studies
- Fairview Clinics and Surgery Center Maple Grove · 2 studies
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cancer trials in other states
Common questions
- Are there cancer clinical trials in Minnesota?
- Yes. We're currently tracking 552 recruiting cancer studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.