Clinical trials · Texas
Cancer clinical trials in Texas
We’re tracking 1,495 recruiting cancer studies with a site in Texas — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Texas
- NCT05039632RecruitingPhase 1/Phase 2
NBTXR3 plus radiation with anti-PD-1 for advanced lung or liver cancers
This study tests whether adding NBTXR3 (given into a tumor) and targeted radiation to anti–PD-1/PD-L1 immunotherapy can improve cancer control in advanced cancers that have spread to the lung and/or liver. Participants may be assigned to different radiation approaches to try to trigger tumor shrinkage in both treated and nearby or distant tumor areas.
Houston, TexasAges 18 years+ - NCT05040360RecruitingPhase 2
Chemotherapy after surgery for high-risk pancreatic NET tumors
This Phase 2 trial studies whether giving chemotherapy after surgery can lower cancer recurrence risk in people with high-risk pancreatic neuroendocrine tumors (NETs). It may help you by testing an added treatment after the tumor has been removed.
Bryan, TexasAges 18 years+ - NCT05048212RecruitingPhase 2
Nivolumab, ipilimumab, and cabozantinib for kidney cancer brain spread
This Phase 2 study tests how well nivolumab plus ipilimumab, along with cabozantinib, treats untreated or worsening kidney cancer that has spread to the brain. It may help shrink brain tumors and slow the disease when standard local brain treatments aren’t the right option.
Houston, TexasAges 18 years+ - NCT05055063RecruitingPhase 1
Belantamab for high-risk smoldering myeloma safety and early benefit
This Phase 1 trial tests belantamab mafodotin, a cancer medicine, in people with high-risk smoldering multiple myeloma to see how safe it is and whether it may shrink or control the disease. Because it’s an early-stage study, you would be closely monitored and treated with one main study drug.
Houston, TexasAges 18 years+ - NCT05056818Recruiting
Compare two types of breast X-ray images for reading accuracy
This study compares a computer-generated (“synthetic”) mammogram to the standard full-field digital mammogram to see which gives better image-reading results. It may help improve how breast images are interpreted in everyday practice.
Houston, TexasAges 18 years+ - NCT05059678Recruiting
Parenting support for families coping with advanced cancer
This study tests a parenting support program for adults who are living with an advanced solid cancer diagnosis and are actively treating it. It may help you and your child’s other parent/caregiver with coping and parenting during this stressful time.
Houston, TexasAges 18 years+ - NCT05064280RecruitingPhase 2
Pembrolizumab plus lenvatinib for brain metastases from solid tumors
This Phase 2 trial studies whether combining pembrolizumab with lenvatinib can shrink or control brain metastases in people with triple-negative breast cancer, lung cancer, or other solid tumors. It focuses on patients who have measurable brain lesions that can be followed on MRI.
Houston, TexasAges 18 years+ - NCT05091372RecruitingPhase 2
Maintenance treatment after transplant for newly diagnosed myeloma
This trial tests whether using belantamab mafodotin plus lenalidomide as long-term maintenance after an autologous stem cell transplant can keep multiple myeloma under control, guided by minimal residual disease (MRD). MRD is a very small amount of disease that may remain after transplant, and the study helps see if treating those patients better improves outcomes.
Houston, TexasAges 18 years+ - NCT05100095RecruitingPhase 2
Radiation schedule study for Merkel cell skin cancer
This Phase 2 trial tests a specific radiation timing/dose schedule for Merkel cell carcinoma (MCC), a rare and aggressive skin cancer. It may help by improving control of the cancer after surgery, especially in higher-risk cases (like lymph nodes).
Houston, TexasAges 18 years+ - NCT05126810Recruiting
Standard versus personalized counseling for TP53 test results
This trial compares standard genetic counseling with a more personalized approach for people considering or receiving TP53 genetic testing. It may help by seeing which counseling style better supports you before and after testing for a TP53 inherited change.
Houston, TexasAges Any age - NCT05132504RecruitingPhase 2
Pre-surgery chemotherapy and immunotherapy for operable pancreatic cancer
This Phase 2 trial tests giving chemotherapy plus pembrolizumab (an immunotherapy) before surgery, to shrink or control potentially removable pancreatic cancer. The goal is to improve outcomes while making sure the cancer can still be safely removed by surgery.
Houston, TexasAges 18 years+ - NCT05136807Recruiting
Quality of life study for people with MGUS or smoldering myeloma
This study looks at how patients feel day to day (quality of life) while they are monitored or treated for MGUS or smoldering multiple myeloma. It is designed for people who do NOT yet have “myeloma defining events” or amyloidosis, because the goal is to understand well-being in earlier disease stages.
Houston, TexasAges 18 years+ - NCT05143619Recruiting
Teaching liver cancer diagnosis to radiologists worldwide
This study looks at whether a “teaching the teachers” approach improves how radiologists understand and apply liver cancer (HCC) diagnosis guidelines. It may help by standardizing how liver imaging results are interpreted across different countries and practice settings.
Houston, TexasAges Any age - NCT05176665RecruitingPhase 1/Phase 2
EMB-01 for advanced stomach, bile, liver, and colon cancers
This early-phase trial studies EMB-01 in people with advanced or metastatic gastrointestinal cancers to see how well it works and how safe it is. To join, your tumor’s DNA or protein pattern (especially EGFR or cMET) must match specific lab results, and you must have tried standard treatments.
Houston, TexasAges 18 years+ - NCT05185505RecruitingPhase 4
Atezolizumab and bevacizumab before liver transplant for liver cancer
This trial tests giving atezolizumab plus bevacizumab before liver transplant in people with hepatocellular carcinoma (HCC) that is too advanced to be listed within the “Milan criteria,” but still transplant-eligible. The goal is to control the cancer outside the transplant period and improve transplant outcomes.
Houston, TexasAges 18 years+ - NCT05195710RecruitingPhase 1
Pre-surgery Y-90 treatment to grow future liver volume
This trial tests a radiation treatment called Y-90 given before liver surgery for colorectal cancer that has spread to the liver. The goal is to help the liver grow enough for safer, curative surgery, either right away or as part of a two-step operation.
Houston, TexasAges 18 years+ - NCT05208047RecruitingPhase 3
CGT9486 plus sunitinib for advanced gastrointestinal stromal tumors
This trial tests whether adding a new drug called CGT9486 to sunitinib (a standard cancer drug) works better than sunitinib alone for gastrointestinal stromal tumors (GISTs) that have grown or spread. You may qualify if your GIST stopped responding to or caused problems with imatinib, an earlier treatment.
Houston, TexasAges 18 years+ - NCT05211895RecruitingPhase 3
Durvalumab plus domvanalimab after chemoradiation for stage 3 lung cancer
This trial studies whether adding durvalumab and domvanalimab after standard chemoradiation can keep unresectable stage 3 lung cancer from coming back or getting worse. It targets tumors with specific lab test results (including PD-L1 and gene markers).
Fort Sam Houston, TexasAges 18 years+ - NCT05245500RecruitingPhase 1
Study drug for solid tumors with MTAP gene deletion
This Phase 1 trial studies MRTX1719, a new medicine, in solid tumors that have a missing MTAP gene (MTAP deletion). It aims to find the safest dose and check how the drug affects the tumor.
Houston, TexasAges 18 years+ - NCT05254327RecruitingPhase 2
Radiation plus or minus BMX-001 for advanced rectal cancer
This Phase 2 study tests two different ways of giving radiation before surgery for locally advanced rectal cancer, with or without an added study drug called BMX-001. It aims to see whether the shorter/longer radiation plans and BMX-001 improve cancer control and are safe.
San Antonio, TexasAges 18 years+ - NCT05271292RecruitingPhase 1/Phase 2
Chiauranib for advanced cancers that returned or won’t respond
This Phase 1/2 study tests chiauranib in people with advanced solid cancers (including small cell lung cancer) that have come back or no longer respond to standard treatments. It aims to find a safe dose and see whether the treatment can help shrink tumors.
Huntsville, TexasAges 18 years+ - NCT05335811RecruitingPhase 1
PET scan test of a new radioactive drug for tumors and inflammation
This Phase 1 study tests whether a new PET imaging tracer (a small amount of radioactive medicine) is safe and how it moves through the body. It’s mainly for adults with cancer who have signs of inflammation or possible immune side effects, so doctors can see what’s happening in the body.
Houston, TexasAges 18 years+ - NCT05336383RecruitingPhase 2
Radiation after prior CAR T for relapsed multiple myeloma
This trial tests giving “salvage” radiation (radiation meant to control remaining cancer) after you’ve already had BCMA CAR-T therapy for multiple myeloma. It’s for people whose PET or other scan still shows active myeloma at least 30 days after CAR-T, and who have a spot that radiation can target.
Houston, TexasAges 18 years+ - NCT05342454Recruiting
Brain tumor surgery patients using brain scan and mapping software
This study checks a new computer software tool that helps doctors map important brain networks and how blood flow responds during brain scans. It may help improve planning and safety for people having brain tumor surgery.
Houston, TexasAges 18 years+
Cancer trials by city in Texas
Where these studies are running in Texas
Institutions with a site for the recruiting cancer studies listed above.
- The University of Texas MD Anderson Cancer Center · 18 studies
- Houston Methodist Hospital · 2 studies
- Baylor College of Medicine
- Baylor St. Luke's Medical Center
- North Houston Cancer Clinics
- Research Site
- St. Joseph Health Regional Hospital
- START San Antonio
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cancer trials in other states
Common questions
- Are there cancer clinical trials in Texas?
- Yes. We're currently tracking 1,495 recruiting cancer studies with a site in Texas, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study in Texas?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Texas to take part?
- Not necessarily. These studies have a site in Texas, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open in Texas regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.