Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 12,855 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04332874RecruitingPhase 2
Pembrolizumab with local limb chemotherapy for sarcoma in arms or legs
This trial tests whether giving pembrolizumab along with chemotherapy delivered directly into an arm or leg (isolated limb infusion) can shrink sarcoma tumors. It is for people with advanced or metastatic sarcoma in an arm or leg who can safely have this local treatment.
Basking Ridge, New JerseyAges 12 years+ - NCT04291651Recruiting
Pancreatic Cyst Registry for Adults With Pancreatic Cysts
This registry study collects information from adults who have a pancreatic cyst (a fluid-filled sac in the pancreas). It may help doctors understand these cysts and how they change over time, which can improve future care.
San Francisco, CaliforniaAges 18 years+ - NCT04294927Recruiting
Tube removal first, then ovaries later for high-risk women
This study looks at whether removing the fallopian tubes first, and the ovaries later, is safe for women with certain inherited gene mutations that raise ovarian cancer risk. It may help you understand a prevention approach when you’re considered high risk and have finished having children.
Chicago, IllinoisAges 25–50 - NCT04118660Recruiting
Thoracic specimen registry for adults with chest conditions
This study is a “specimen registry,” meaning it collects and stores samples from adults with chest (thoracic) diseases. It may help researchers better understand lung and chest conditions and improve future testing or treatments.
Rochester, MinnesotaAges 18 years+ - NCT04024917Recruiting
Cardiac coherence training to reduce anxiety before abdominal surgery
This trial tests whether “cardiac coherence” breathing/relaxation practice can lower anxiety in people with peritoneal cancer who are scheduled for a major surgery. It may help by calming stress before and around the operation.
Montpellier, HéraultAges 18 years+ - NCT04224974Recruiting
Engagement and symptom support for newly diagnosed acute leukemia
This trial tests an emotion- and symptom-focused way of engaging with care for people who are newly diagnosed with acute leukemia and starting intensive “induction” treatment aimed at cure. It may help you feel better supported and better able to manage distressing symptoms during a critical early phase of treatment.
Saint John, New BrunswickAges 18 years+ - NCT04239573Recruiting
Compare pancreatic cyst checkup programs and test markers
This study compares different ways to monitor pancreatic cysts and also measures blood or other test markers to see which approach is more helpful. It may help patients by finding the safest, most effective way to track certain cysts that could otherwise be hard to manage.
Birmingham, AlabamaAges 50–75 - NCT04166409RecruitingPhase 3
Selumetinib versus chemo for low-grade brain tumor in children
This trial studies whether the targeted drug selumetinib works better than standard chemotherapy (carboplatin and vincristine) for children and young adults with a specific type of low-grade glioma (grade 1 or 2). It may help shrink tumors and slow growth while comparing side effects between the two treatment approaches.
Birmingham, AlabamaAges 2–21 - NCT04216524RecruitingPhase 2
Venetoclax plus chemotherapy for blastic dendritic cell cancer
This Phase 2 trial tests venetoclax combined with chemotherapy to treat blastic plasmacytoid dendritic cell neoplasm (BPDCN). It may help shrink BPDCN and control the disease, whether you’re newly diagnosed or the cancer has come back.
Houston, TexasAges 18 years+ - NCT04174079Recruiting
Chemotherapy after esophagus surgery for lymph node spread
This trial studies whether adding chemotherapy after surgery for esophageal squamous cell cancer can reduce the chance the cancer returns. It focuses on people whose surgery removed cancerous lymph nodes and who are healthy enough to tolerate chemotherapy.
Guangzhou, GuangdongAges 18–75 - NCT04239157RecruitingPhase 2
Canakinumab shot for lower-risk MDS and related blood disorders
This trial tests canakinumab, a medication that blocks inflammation, given as a skin (subcutaneous) injection. It is for adults with lower-risk myelodysplastic syndromes (MDS) or a related condition (chronic myelomonocytic leukemia or CCUS) to see if it can improve blood counts and reduce problems like anemia or transfusion needs.
Houston, TexasAges 18 years+ - NCT04165772RecruitingPhase 2
Dostarlimab for locally advanced mismatch-repair deficient solid tumors
This Phase 2 trial studies dostarlimab (an immune therapy that targets PD-1) given before surgery or other initial treatment. It aims to shrink certain locally advanced cancers that have mismatch repair deficiency, potentially making treatment easier and improving outcomes.
Hartford, ConnecticutAges 18 years+ - NCT04223765RecruitingPhase 1
Testing a new CAR T-cell treatment for kappa cancers
This Phase 1 trial studies a lab-made immune therapy (CAR T cells) that targets “kappa” markers on certain lymphomas and CLL/SLL. It’s for people whose cancer has come back or didn’t respond to standard treatments, aiming to improve control of the disease.
Chapel Hill, North CarolinaAges 18 years+ - NCT04207437Recruiting
Daily handheld vibration therapy for chemotherapy nerve pain
This trial studies whether daily handheld vibration can lessen nerve damage symptoms in the hands after certain chemotherapy medicines. It may help reduce numbness, tingling, or pain from chemotherapy-related nerve problems.
Avon, IndianaAges 18 years+ - NCT04199026Recruiting
Tiny implanted device delivers drugs to sarcoma tumors
This trial tests an implantable device placed during planned surgery to deliver cancer medicines directly to sarcoma tumors and study how they affect the tumors. It may be an option if your sarcoma has come back or spread and surgery is part of standard care.
Houston, TexasAges 10 years+ - NCT04218617RecruitingPhase 2
One vs two radiation treatments for spine metastases
This trial tests whether giving radiation to a spine metastasis in one dose works as well as giving it in two smaller doses. It aims to control tumors while keeping side effects and risk to the spinal cord low.
Cleveland, OhioAges 18 years+ - NCT04175431RecruitingPhase 2
PSMA or FACBC PET scan guided treatment for prostate cancer recurrence
This Phase 2 study tests using a special PET/CT scan (PSMA or FACBC) to guide treatment for prostate cancer that has come back after surgery and radiation. The goal is to see whether this scan-based approach can better target cancer in the prostate area (and help plan the right treatment).
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04202094Enrolling by invitation
Fertility options for young men after childhood cancer treatment
This study looks at fertility outcomes in young men who had cancer or blood disorders as children and then received high-risk treatment that can affect future fertility. It also compares people who did or did not store testicular tissue through a biopsy when they were younger.
BrusselsAges 18 years+ - NCT04251052Recruiting
Compare two surgeries to lower ovarian cancer risk in BRCA1 carriers
This study compares two risk-reducing surgery plans for people with a BRCA1 genetic change to see which approach helps lower ovarian cancer risk. You may be asked to have the study procedure sooner or later depending on your chosen plan.
Birmingham, AlabamaAges 35–50 - NCT04195633RecruitingPhase 2
Haploidentical donor stem cell transplant to treat blood cancers
This Phase 2 trial tests whether a specific stem cell transplant method (from a related “half-matched” donor) plus conditioning chemo and radiation can improve outcomes for several blood cancers. It may help people whose cancer is in remission but still considered high risk, or those who have had limited response after prior treatment.
Seattle, WashingtonAges 6 months+ - NCT04185935Recruiting
Genetic study of cancer in patients and their families
This study looks at DNA patterns in families where cancer may run in families, to better understand inherited (passed-down) cancer risk. You may be able to help even if you’re not sure whether your cancer is genetic—your family history and, if needed, medical records or tumor samples can be used.
Phoenix, ArizonaAges Any age - NCT04169737RecruitingPhase 2
Acalabrutinib and venetoclax for high-risk CLL or SLL
This trial tests whether acalabrutinib and venetoclax (with or without early obinutuzumab) can control chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). It is mainly for people whose disease is high-risk, has come back, or did not respond to earlier treatment.
Houston, TexasAges 18 years+ - NCT04157127RecruitingPhase 1
Pancreatic cancer vaccine with chemotherapy before/around surgery
This early-stage trial tests a personalized immune “vaccine” made from dendritic cells, given alongside standard chemotherapy for pancreatic cancer that may be removable by surgery (resectable or borderline resectable). If it works, it may help your immune system better recognize and attack the cancer around the time of treatment.
Houston, TexasAges 18 years+ - NCT04165070RecruitingPhase 1/Phase 2
Stage IV lung cancer trial using pembrolizumab with or without chemotherapy
This Phase 1/2 study tests pembrolizumab (an immune-based cancer treatment) either alone or with chemotherapy in people newly diagnosed with stage IV non-small cell lung cancer (NSCLC). It looks at how well the treatments work and whether they are safe, especially in people who haven’t had treatment yet for metastatic disease.
Gilbert, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 12,855 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.