Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06934798RecruitingPhase 4
Vasopressin vs. Noradrenaline for low blood pressure after heart surgery
This trial compares two medications, vasopressin and noradrenaline, to see which one works better at raising blood pressure in patients who develop dangerously low blood pressure (vasoplegic syndrome) within the first day after heart surgery. The goal is to find the safest and most effective treatment to stabilize blood pressure and help recovery.
São PauloAges 18 years+ - NCT06251713Recruiting
Fluid removal guided by VeXUS score after heart surgery
This trial tests if using a special ultrasound score (VeXUS) to guide fluid removal can improve recovery in patients with acute kidney injury after heart surgery. It compares this approach to standard care to see if it leads to better outcomes.
Bron, BronAges 18–85 - NCT05879432RecruitingPhase 2
Peptide treatment to prevent or lessen kidney injury after heart surgery
This Phase 2 trial tests an LSALT peptide given around the time of “on-pump” heart surgery to help prevent or reduce acute kidney injury (a sudden drop in kidney function). It may help people who are at higher risk for kidney injury during or after surgery.
Calgary, AlbertaAges 18 years+ - NCT04284839RecruitingPhase 3
Blood thinner pills vs warfarin after heart surgery
This trial compares two ways to prevent blood clots after open heart surgery: a “direct oral” blood thinner pill versus warfarin (a vitamin K antagonist). It may help find the safest and most effective option for people who develop atrial fibrillation after surgery.
Fitzroy, VictoriaAges 18 years+ - NCT04241328Recruiting
Cardiac surgery registry for patients who used a Medtronic device
This study tracks patients who had cardiac surgery using a specific Medtronic heart-surgery device. It mainly collects real-world data to help understand outcomes, and you may be included if you give consent and are not in another device/drug study that could affect the results.
ViennaAges Any age - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT06626035RecruitingPhase 3
Pain Medicine Study for Children Having Heart Surgery
This study tests a pain medicine for children having heart surgery. It aims to see if the medicine works well and is safe for managing pain after the operation.
Oakland, CaliforniaAges 3–18 - NCT07541222Recruiting
Blood pressure medications and surgery recovery outcomes
This study looks at how blood pressure medications affect low blood pressure episodes that happen during and after heart surgery. Researchers want to understand if the number of blood pressure drugs you take before surgery changes how your body handles blood pressure during the operation.
KonyaAges 40 years+ - NCT06710353Recruiting
Albumin before heart surgery for kids with low albumin
This study tests whether giving albumin (a protein in the blood) before heart surgery helps protect the kidneys of young children with low albumin levels. It may help reduce the risk of kidney injury after surgery.
Seoul, SeoulAges Up to 7 years - NCT07024420Recruiting
Sigh breathing during heart surgery with heart-lung machine
This study tests if adding occasional deep breaths (sighs) during heart surgery helps patients recover better after using the heart-lung machine. It is for people having planned (not emergency) heart surgery.
Nanjing, JiangsuAges 18 years+ - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06371976Recruiting
Stress hormone system study after heart surgery
This study looks at how your body's stress hormone system (the HPA axis) works after heart surgery if you develop vasoplegic syndrome (a serious drop in blood pressure). The goal is to understand if giving extra steroids might help. If you are scheduled for heart surgery with a heart-lung machine, you may be able to join.
Paris, Île-de-France RegionAges 18 years+ - NCT06287619RecruitingPhase 2
IV iron after heart surgery for iron deficiency
This trial tests whether giving iron through a vein after heart surgery can help fix low iron levels and improve recovery. It is for people who have iron deficiency (with or without anemia) before their planned heart surgery.
Kingston, OntarioAges 18 years+ - NCT06958029Recruiting
Heart rhythm after heart surgery study
This study looks at how often a fast, irregular heartbeat (atrial fibrillation) happens after heart valve or bypass surgery. Knowing this could help doctors take better care of patients after these procedures.
Khon KaenAges 18 years+ - NCT06840327Recruiting
Oxygen levels during heart bypass surgery and recovery
This study looks at how different oxygen levels during heart bypass surgery might affect recovery. It aims to see if keeping oxygen at a certain level can improve outcomes for people having surgery where a vein from the leg is used to bypass a blocked heart artery.
ToulouseAges 18 years+ - NCT06487585RecruitingPhase 4
Angiotensin II as first pressor after heart surgery
This trial tests if starting Angiotensin II early, instead of other blood pressure medications, can help heart surgery patients maintain safe blood pressure. It may be an option if you have low blood pressure after surgery despite receiving fluids.
Towson, MarylandAges 18 years+ - NCT06425614Recruiting
Blood Cell Recycling During Heart Surgery Trial
This trial tests whether giving back a patient's own platelets and red blood cells during heart surgery can reduce bleeding and the need for donor blood transfusions. It is for people having certain types of high-risk heart surgery with a heart-lung machine.
Bordeaux, FranceAges 18 years+ - NCT07285187Recruiting
Vein congestion and confusion after heart surgery trial
This trial looks at how blood backing up in veins after heart surgery might relate to delirium (sudden confusion). It uses a special ultrasound to check vein blood flow and then watches for confusion afterward.
Yangzhou, JiangsuAges 18 years+ - NCT07483151Recruiting
Heart Surgery and Thinking Changes Study
This study looks at how changes in blood flow (called venous congestion) after heart surgery might affect thinking and memory. It aims to find out if there is a link between how blood returns to the heart and brain function after surgery.
Yangzhou, JiangsuAges 18 years+ - NCT07683299Recruiting
New heart monitoring during bypass surgery
This study tests a new way to monitor your heart and blood flow during heart surgery that uses a heart-lung machine. The goal is to see if this integrated approach helps doctors make better decisions during the operation.
Medellín, AntioquiaAges 18 years+ - NCT07549243Recruiting
Ear Nerve Stimulation to Protect Kidneys During Heart Surgery
This trial tests whether gentle electrical stimulation applied to your ear can help protect your kidneys during heart surgery that uses a heart-lung machine. Kidney damage after this type of surgery is common, and researchers want to see if this non-invasive stimulation can prevent it.
Hangzhou, ZhejiangAges 18 years+ - NCT06534372Recruiting
Factors affecting chronic pain after open-heart surgery
This study looks at factors that may lead to long-term pain after open-heart surgery. It follows patients who have coronary bypass or valve surgery to understand what might cause ongoing pain.
Ankara, AnkaraAges 18–80 - NCT07081009Recruiting
Heart injury after planned back surgery study
This study is looking at whether patients having planned lower back surgery experience any heart stress afterward. It aims to understand how common this is and what might help protect the heart.
AnkaraAges 18 years+ - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55
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Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 295 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.