Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 311 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06817005Recruiting
Pain monitoring during heart surgery
This trial tests a device to measure pain during heart surgery using a heart-lung machine. It may help doctors better manage your pain during the procedure.
StrasbourgAges 18 years+ - NCT06396767Recruiting
Breathing test before heart surgery to predict lung problems
This study uses a simple breathing test before scheduled heart surgery to see if it can help predict breathing or lung complications after the operation. The results may help doctors identify patients who need extra support during recovery.
London, OntarioAges 19–99 - NCT07699016Recruiting
Hemostatic agent use in heart and blood vessel surgery
This trial surveys surgeons about how they use hemostatic agents (medications that stop bleeding during surgery). It aims to understand current practices and improve patient safety.
Milan, MIAges 18 years+ - NCT06251713Recruiting
Fluid removal guided by VeXUS score after heart surgery
This trial tests if using a special ultrasound score (VeXUS) to guide fluid removal can improve recovery in patients with acute kidney injury after heart surgery. It compares this approach to standard care to see if it leads to better outcomes.
Bron, BronAges 18–85 - NCT04241328Recruiting
Cardiac surgery registry for patients who used a Medtronic device
This study tracks patients who had cardiac surgery using a specific Medtronic heart-surgery device. It mainly collects real-world data to help understand outcomes, and you may be included if you give consent and are not in another device/drug study that could affect the results.
ViennaAges Any age - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT05879432RecruitingPhase 2
Peptide treatment to prevent or lessen kidney injury after heart surgery
This Phase 2 trial tests an LSALT peptide given around the time of “on-pump” heart surgery to help prevent or reduce acute kidney injury (a sudden drop in kidney function). It may help people who are at higher risk for kidney injury during or after surgery.
Calgary, AlbertaAges 18 years+ - NCT06625892Recruiting
Fear of movement after heart surgery
This study looks at why some people fear moving after heart surgery and tests a program to help them overcome that fear. It aims to improve recovery and quality of life.
ChanghuaAges 18–100 - NCT06934798RecruitingPhase 4
Vasopressin vs. Noradrenaline for low blood pressure after heart surgery
This trial compares two medications, vasopressin and noradrenaline, to see which one works better at raising blood pressure in patients who develop dangerously low blood pressure (vasoplegic syndrome) within the first day after heart surgery. The goal is to find the safest and most effective treatment to stabilize blood pressure and help recovery.
São PauloAges 18 years+ - NCT07221617RecruitingPhase 4
Methadone for pain after heart surgery
This trial tests whether a single dose of methadone given during heart surgery can improve pain control and recovery. It may be an option for people having planned (not emergency) heart surgery.
Rochester, MinnesotaAges 18 years+ - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT06626035RecruitingPhase 3
Pain Medicine Study for Children Having Heart Surgery
This study tests a pain medicine for children having heart surgery. It aims to see if the medicine works well and is safe for managing pain after the operation.
Pittsburgh, PennsylvaniaAges 3–18 - NCT06287619RecruitingPhase 2
IV iron after heart surgery for iron deficiency
This trial tests whether giving iron through a vein after heart surgery can help fix low iron levels and improve recovery. It is for people who have iron deficiency (with or without anemia) before their planned heart surgery.
Kingston, OntarioAges 18 years+ - NCT07541222Recruiting
Blood pressure medications and surgery recovery outcomes
This study looks at how blood pressure medications affect low blood pressure episodes that happen during and after heart surgery. Researchers want to understand if the number of blood pressure drugs you take before surgery changes how your body handles blood pressure during the operation.
KonyaAges 40 years+ - NCT07024420Recruiting
Sigh breathing during heart surgery with heart-lung machine
This study tests if adding occasional deep breaths (sighs) during heart surgery helps patients recover better after using the heart-lung machine. It is for people having planned (not emergency) heart surgery.
Nanjing, JiangsuAges 18 years+ - NCT06371976Recruiting
Stress hormone system study after heart surgery
This study looks at how your body's stress hormone system (the HPA axis) works after heart surgery if you develop vasoplegic syndrome (a serious drop in blood pressure). The goal is to understand if giving extra steroids might help. If you are scheduled for heart surgery with a heart-lung machine, you may be able to join.
Paris, Île-de-France RegionAges 18 years+ - NCT06710353Recruiting
Albumin before heart surgery for kids with low albumin
This study tests whether giving albumin (a protein in the blood) before heart surgery helps protect the kidneys of young children with low albumin levels. It may help reduce the risk of kidney injury after surgery.
Seoul, SeoulAges Up to 7 years - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06840327Recruiting
Oxygen levels during heart bypass surgery and recovery
This study looks at how different oxygen levels during heart bypass surgery might affect recovery. It aims to see if keeping oxygen at a certain level can improve outcomes for people having surgery where a vein from the leg is used to bypass a blocked heart artery.
ToulouseAges 18 years+ - NCT06425614Recruiting
Blood Cell Recycling During Heart Surgery Trial
This trial tests whether giving back a patient's own platelets and red blood cells during heart surgery can reduce bleeding and the need for donor blood transfusions. It is for people having certain types of high-risk heart surgery with a heart-lung machine.
Bordeaux, FranceAges 18 years+ - NCT06487585RecruitingPhase 4
Angiotensin II as first pressor after heart surgery
This trial tests if starting Angiotensin II early, instead of other blood pressure medications, can help heart surgery patients maintain safe blood pressure. It may be an option if you have low blood pressure after surgery despite receiving fluids.
Towson, MarylandAges 18 years+ - NCT06958029Recruiting
Heart rhythm after heart surgery study
This study looks at how often a fast, irregular heartbeat (atrial fibrillation) happens after heart valve or bypass surgery. Knowing this could help doctors take better care of patients after these procedures.
Khon KaenAges 18 years+ - NCT07285187Recruiting
Vein congestion and confusion after heart surgery trial
This trial looks at how blood backing up in veins after heart surgery might relate to delirium (sudden confusion). It uses a special ultrasound to check vein blood flow and then watches for confusion afterward.
Yangzhou, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 311 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.