Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06722196RecruitingPhase 3
Amiodarone patch to prevent afib after heart surgery
This trial tests a biodegradable patch that slowly releases amiodarone directly onto the heart during surgery. It aims to prevent atrial fibrillation, a common irregular heartbeat after heart surgery.
Changchun, JinlinAges Any age - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06668831Recruiting
FGF23 and heart rhythm in dialysis patients
This study looks at whether a blood protein called FGF23 is linked to irregular heartbeats in people on long-term hemodialysis (kidney dialysis). It may help doctors better predict heart risks.
LuganoAges 18 years+ - NCT05564793Recruiting
Noninvasive heart mapping to improve CRT outcomes
This trial tests whether a special noninvasive heart “mapping” test done on the body can help improve outcomes for people who need a CRT device. It studies whether mapping before implantation can better guide or predict how well the CRT will work.
AmsterdamAges 18–85 - NCT06705751Recruiting
Faster diagnosis of abnormal coronary artery origin
This study tests a new, faster way to diagnose an uncommon heart condition where one of the main arteries (the coronary artery) starts from the wrong place on the aorta. The goal is to help doctors find and treat it sooner.
San Donato Milanese, ItaliaAges 6 years+ - NCT06711016Recruiting
Managing brain oxygen after emergency life support
This trial tests a targeted approach to manage oxygen levels in the brain for patients who received ECMO (a machine that does the heart and lung work) after a cardiac arrest that did not respond to standard CPR. The goal is to improve brain recovery and outcomes.
Jinan, ShandongAges 18–75 - NCT06699056Recruiting
AI heart monitor study for ejection fraction
This study uses an AI-powered wearable monitor to check how well your heart pumps blood (ejection fraction) from a simple EKG recording. It may help doctors quickly assess heart function without extra tests.
Orange, CaliforniaAges 18 years+ - NCT06703489Recruiting
New catheter for ventricular tachycardia
This trial tests a new catheter system (Sphere-9 and Affera) to treat a fast, dangerous heartbeat called ventricular tachycardia (VT) in people with heart scarring. It aims to see if this system is safe and effective at stopping VT, especially if past treatments haven't worked.
Boston, MassachusettsAges 18–85 - NCT06693674RecruitingPhase 3
Sacubitril-valsartan for heart health in congenital heart disease
This trial tests if a drug called sacubitril-valsartan can improve heart structure and function in adults with congenital heart disease. You will take the drug and have heart imaging to see changes.
Rochester, MinnesotaAges 18 years+ - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT06689111Recruiting
Heart resynchronization method study for patients with LBBB and heart failure
This study compares two ways to resynchronize the heart's pumping in people with heart failure and a specific heart block (LBBB). It uses special ultrasound imaging to see which method works better for improving heart function.
Pátrai, GreeceAges 18–90 - NCT06679543Recruiting
How partial sleep loss affects heart function during cycling
This study looks at how a night of poor sleep affects your heart's ability to pump blood while you ride a bike. It may help find out why sleep loss can be hard on the heart.
Guelph, OntarioAges 18–50 - NCT05989139Recruiting
Oxygen mask vs. breathing machine for sudden fluid in the lungs
This trial compares two ways to help people who have a sudden buildup of fluid in the lungs (acute pulmonary edema) breathe easier. One uses a simple oxygen mask, the other uses a machine that pushes air into your lungs. The results may help doctors choose the best treatment for you.
RomaAges 18 years+ - NCT06661876Recruiting
Heart radiation therapy for heart failure
This trial tests if a low dose of radiation to the heart can help people with advanced heart failure feel better and improve heart function. It is for patients whose heart failure is stable but severe, and who are already on the best medications.
LeuvenAges 18 years+ - NCT06651970RecruitingPhase 4
Acalabrutinib for chronic lymphocytic leukemia with heart problems
This trial tests a targeted therapy called acalabrutinib (a pill) against other standard treatments for chronic lymphocytic leukemia (CLL) in people who also have heart conditions. The goal is to see if acalabrutinib is a safer or more effective option for this group.
Charlotte, North CarolinaAges 18–130 - NCT06650579RecruitingPhase 3
Heart safety study of relugolix vs leuprolide for prostate cancer
This trial compares two hormone therapy combinations for men with prostate cancer that hasn't spread. The goal is to see if a newer oral medication (Relugolix) plus abiraterone works better than the standard injectable therapy (Lupron) plus abiraterone, while also checking heart safety.
Atlanta, GeorgiaAges 18 years+ - NCT06627543Enrolling by invitation
Enzyme replacement therapy for heart health in Gaucher type 3
This study looks at how enzyme replacement therapy affects heart function in children with Gaucher disease type 3. It aims to see if the therapy helps keep the heart healthy.
AsyutAges Any age - NCT06628973Recruiting
Social activities for women with heart failure
This trial tests a social program to help women with heart failure better stick with their medications and feel healthier. You'll be connected to community activities and support tailored to your needs.
Montreal, QuebecAges 18 years+ - NCT06620523RecruitingPhase 2
Preventing kidney injury after heart bypass surgery
This trial tests whether combining two natural supplements (CoQ10 and glutathione) can protect your kidneys during heart bypass surgery. It may help prevent acute kidney injury, a common complication after these procedures.
Washington D.C., District of ColumbiaAges 18–70 - NCT06602609Recruiting
Remote heart monitoring after TAVI valve procedure
This trial tests whether patients can go home the same day after TAVI and use a smart device for remote monitoring. It aims to see if this approach is safe and effective for recovery.
LondonAges 18 years+ - NCT06595615Enrolling by invitation
Heart health app data collection study
This trial gathers health data from a smartphone app to learn more about heart failure in people with a specific type of implanted heart device. The information will help doctors better understand how to treat and manage heart failure.
Huntsville, AlabamaAges 18 years+ - NCT06597331Recruiting
Heart function study for COPD flare-ups
This study looks at how a COPD flare-up might affect the heart in people who haven't had a heart attack or known heart muscle damage before. It uses a simple heart ultrasound to check for stress-related changes.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT06578104Recruiting
Pulsed AF Study: PulseSelect Catheter for Afib
This study tests a new way to treat atrial fibrillation (Afib) using a special catheter system called PulseSelect that delivers short bursts of energy to create scar tissue in the heart. It is for people whose Afib comes and goes or stays for a while but not more than a year, and who have not had a prior ablation procedure or have a pacemaker or defibrillator.
Tampa, FloridaAges 18 years+ - NCT06579807Recruiting
Cardiac rehab for coronary artery disease
This study tests if a cardiac rehabilitation program helps people with coronary artery disease. You can join if you are between 40 and 70, have heart disease (or are a healthy volunteer), and do not have other health issues like heart failure or smoking.
Rio de Janeiro, Rio de JaneiroAges 40–70
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Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,291 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.