Clinical trials
Cardiomyopathies clinical trials
Below are recruiting cardiomyopathies clinical trials, each written for real people, not researchers. We’re tracking 322 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07218887RecruitingPhase 1/Phase 2
A study of ALXN2350 for BAG3-related heart muscle disease
This trial tests a new medicine, ALXN2350, for adults whose dilated cardiomyopathy (a weakened, enlarged heart) is caused by a mutation in the BAG3 gene. The goal is to see if it can help the heart pump better.
Birmingham, AlabamaAges 18–70 - NCT06412666RecruitingPhase 2/Phase 3
Aficamten for teens with obstructive hypertrophic cardiomyopathy
This trial tests a new medicine called aficamten for teenagers with a heart condition that makes the heart muscle too thick and blocks blood flow. The medicine may help make the heart pump more easily and improve symptoms like shortness of breath or chest pain.
Phoenix, ArizonaAges 12–17 - NCT07298044RecruitingPhase 4
Switching from tafamidis to acoramidis for heart condition
This study checks how levels of a protein called transthyretin change in your blood when you switch from tafamidis to acoramidis. It is for people with a specific type of heart disease caused by abnormal protein buildup.
Sankt Pölten, Lower AustriaAges 18–90 - NCT06898762Recruiting
National study on inflammatory heart disease for patients with symptoms
This study is creating a national registry to learn more about inflammatory myocardial disease (inflammation of the heart muscle). If you have symptoms like chest pain, shortness of breath, palpitations, or certain test results, you may be eligible to join and help advance research.
Murcia, MurciaAges 18 years+ - NCT05888662Recruiting
Compare two catheter approaches to treat ventricular tachycardia
This study compares an “outer heart” catheter approach (epicardial) versus an “inner heart” approach (endocardial-only) to treat a dangerous heart rhythm called ventricular tachycardia. It aims to see which approach works better and is safest for people with ischemic heart disease who are having their first ablation.
BordeauxAges 18 years+ - NCT06641830Enrolling by invitation
Study of cardiomyopathy in children
This trial studies children with cardiomyopathy to better understand the condition. It's for children who have been diagnosed with cardiomyopathy and who do not have other major heart problems or serious issues with other organs.
Chengdu, SichuanAges Up to 18 years - NCT06539208RecruitingPhase 1/Phase 2
Study of YOLT-201 for transthyretin amyloidosis with nerve or heart damage
This trial tests an experimental gene-editing medicine called YOLT-201 for people with a type of amyloidosis that damages nerves or the heart. It aims to see if one or two doses can safely stop the disease from getting worse.
Beijing, Beijing MunicipalityAges 18–80 - NCT06352307Recruiting
Prevention and treatment strategies for arrhythmogenic cardiomyopathy
This trial evaluates early prevention and treatment strategies for arrhythmogenic cardiomyopathy (ACM), a heart condition that can cause abnormal heart rhythms. It aims to improve care by using advanced tests like heart imaging and genetic sequencing to guide treatment.
Xi'an, ShaanxiAges 18 years+ - NCT05507879Recruiting
Breast cancer heart monitoring to predict heart damage risk
This trial studies how a blood test marker (TRPC6) may help predict and prevent heart muscle damage and heart failure related to some breast cancer medicines. You may join if you’re starting or have received treatment that can stress the heart, or if you already have signs of treatment-related heart problems.
Gainesville, FloridaAges 18 years+ - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
La Jolla, CaliforniaAges 18–75 - NCT07081711Recruiting
Testing new heart MRI technology in volunteers
This study is testing a new way to take pictures of the heart using MRI. It is looking for healthy volunteers to help make sure the technology works correctly.
Cleveland, OhioAges 18 years+ - NCT07695701RecruitingPhase 4
Heart imaging study for a new ATTR-CM treatment
This trial uses heart scans to see how the drug acoramidis affects heart structure and function in people with a specific type of heart disease called ATTR cardiomyopathy. It may help doctors understand if the treatment is working.
St Louis, MissouriAges 18–80 - NCT07398950Recruiting
AI screening for a heart condition called ATTR-CM
This study uses artificial intelligence (AI) to look at your heart tests (ECG and echo) and find people who might have a specific heart muscle disease called ATTR-CM. The goal is to catch it earlier so treatment can start sooner.
New Haven, ConnecticutAges 18 years+ - NCT07721025RecruitingPhase 2
Gene therapy trial for Friedreich ataxia heart disease
This trial tests a one-time gene therapy called LX2006 for heart problems caused by Friedreich ataxia. The goal is to see if it can improve heart function and structure.
Tampa, FloridaAges 6 years+ - NCT03299569Recruiting
Learn how often Tako-tsubo heart weakness happens in Scotland
This study aims to measure how many people in Scotland develop Tako-tsubo cardiomyopathy (a temporary heart condition often triggered by stress or illness). It may help doctors better understand who is affected and plan care in the future.
Aberdeen, ScotlandAges Any age - NCT03663348Recruiting
Patient registry for Takotsubo (stress) heart syndrome
This study is a patient registry that collects information from people diagnosed with Takotsubo syndrome, also known as a stress-related heart condition. It may help researchers learn more about who is affected and how the condition behaves over time.
New York, New YorkAges 18–110 - NCT03846297Recruiting
Decision support for defibrillator placement in hypertrophic cardiomyopathy
This trial looks at how to make better decisions about whether someone with hypertrophic cardiomyopathy (HCM) should get an implantable heart defibrillator. It may help by using structured decision support to guide defibrillator implantation.
Boulogne-Billancourt, Hauts-de-SeineAges 16 years+ - NCT06902896RecruitingPhase 1/Phase 2
FAP iCDC therapy for advanced heart failure from dilated cardiomyopathy
This trial tests a new treatment called FAP iCDC for people with end-stage dilated cardiomyopathy, a type of heart muscle disease. It aims to see if this therapy is safe and helps improve heart function when standard medicines are no longer enough.
Hangzhou, ZhejiangAges 18–75 - NCT04513054Recruiting
Genetic study for stress-related heart muscle weakness
This study looks for a possible inherited (genetic) reason some people develop Takotsubo cardiomyopathy after severe stress. If you’ve had this condition, the study may help explain why it happens and whether families could be at higher risk.
Aberdeen, AberdeenshireAges Any age - NCT04521790Recruiting
Biopsy-guided treatment for suspected inflammation of the heart
This study looks at people 18 and older with suspected myocarditis (inflammation of the heart). It uses an inner-heart biopsy and tailored treatment based on the likely cause to improve diagnosis and care, especially for people with different heart rhythm or non-rhythm symptoms.
Milan, MilanoAges 18 years+ - NCT04612296Recruiting
Heart Hive study for cardiomyopathy and family history
This observational study looks at people with cardiomyopathy or myocarditis, and people with a close family history of these conditions. It aims to better understand the condition and what factors may be involved.
LondonAges 18 years+ - NCT04654988RecruitingPhase 4
Immunosuppression study for active myocarditis or inflammatory cardiomyopathy
This Phase 4 study tests whether weakening the immune system (immunosuppression) works better for people with active myocarditis or inflammatory cardiomyopathy. It includes extra heart tests—two heart muscle biopsies and two heart MRI scans—to confirm the diagnosis and guide treatment.
WarsawAges 18–65 - NCT04990297Recruiting
MRI test to better predict risk in dilated heart muscle
This trial uses a heart MRI to measure details in people with dilated cardiomyopathy and reduced pumping strength. It aims to use these MRI findings to better predict your future heart risk and guide care.
Beijing, Beijing MunicipalityAges Any age - NCT05112237Recruiting
Study of children’s heart disease caused by MYBPC3 gene changes
This is an observational study that follows children under 18 with cardiomyopathy caused by certain MYBPC3 gene mutations. It aims to better understand how the disease changes over time, which may help future treatments be better targeted.
Little Rock, ArkansasAges birth–18 years
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Common questions
- Are there clinical trials for cardiomyopathies?
- Yes. Clin2 currently lists 322 recruiting cardiomyopathies studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiomyopathies trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiomyopathies trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.