Clinical trials
Cardiovascular Disease Risk Factor clinical trials
Below are recruiting cardiovascular disease risk factor clinical trials, each written for real people, not researchers. We’re tracking 159 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03083405Enrolling by invitation
Study of tooth grinding during sleep
This study is for adults who have been diagnosed with sleep bruxism (tooth grinding during sleep). Researchers want to understand it better using sleep testing, and it may help refine how this condition is evaluated.
WroclawAges 18–70 - NCT00001853Recruiting
Heart disease risk study in Black adults
This study looks at how obesity and blood fat (triglyceride) levels affect heart disease risk differently in Black men and women. You may join if you're a healthy Black adult between 18 and 70, without diabetes.
Bethesda, MarylandAges 18–70 - NCT06600737Recruiting
Heart health in people with inflammatory diseases
This study looks at how inflammatory diseases (like rheumatoid arthritis or psoriasis) affect heart health. It aims to understand and improve heart disease risk in people with these conditions, whether they have had a heart event or not.
Manchester, Greater ManchesterAges 18 years+ - NCT07416344Enrolling by invitation
Heart CT screening for high-risk rural patients
This trial uses a heart CT scan to find people in rural China who are at high risk for heart disease but haven't had a heart attack or stroke yet. The goal is to see if this screening can help guide treatment and prevent future heart problems.
Daqing, HeilongjiangAges 40–75 - NCT06425120RecruitingPhase 4
Xuesaitong for heart disease risk factors
This trial tests whether Xuesaitong soft capsules can improve major risk factors in people with stable coronary heart disease who are already on cholesterol-lowering and antiplatelet medications. You may be able to join if you have chronic coronary artery disease and certain signs of inflammation.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04294771Recruiting
Heart problems linked to cancer immunotherapy drugs
This study looks at reports from large health databases to find out if certain cancer drugs (checkpoint inhibitors) cause heart problems. It aims to understand which patients have a higher risk, which may help doctors watch for heart issues in the future.
ParisAges Any age - NCT05334888Recruiting
Study how sex and gut bacteria relate to heart risk
This study follows people over time to understand how sex-related factors and gut bacteria may affect heart and blood-vessel risk. It may help researchers identify who could benefit from earlier prevention, based on personal risk patterns.
BerlinAges 18–50 - NCT07391293Recruiting
Genetic aortic diseases and heart risks observational study
This study looks at people with genetic aortic diseases to understand risk factors for heart complications. By joining, you help researchers learn more about these conditions and how to better manage them.
MilanAges 14–60 - NCT05466825Recruiting
Using health data to study cardiovascular risk
This study brings together existing health information to understand how common heart-risk factors relate to heart outcomes. It may help improve how future risk is predicted and prevented, especially in people who have not yet had heart disease.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT07370727Recruiting
Weight training for kidney transplant patients
This trial studies whether a personalized weight training program helps kidney transplant recipients improve their strength and health. It is for people who are at least one year post-transplant and have stable kidney function.
Bogotá, Bogota D.C.Ages 18–50 - NCT05708807Recruiting
Follow-up study of recovery after first-time stroke in Gothenburg
This study tracks how people recover after their first-ever stroke (either blocked artery stroke or bleeding in the brain). It may help doctors better understand recovery patterns and what support could work best over time.
GothenburgAges 18 years+ - NCT06627322Recruiting
Diabetes type 2 trial for people with heart risks
This study compares different diabetes medicines to see which works best for people with type 2 diabetes who also have heart or blood vessel risks. It aims to find better treatment to protect your heart and kidneys.
DaeguAges 19 years+ - NCT07113223Recruiting
AI heart test for heart failure detection in people over 65
This trial uses an artificial intelligence system to analyze electrocardiograms (ECGs, which are recordings of your heart's electrical activity) to detect heart failure early. It is for people over 65 who either have symptoms that might be heart failure or have risk factors for heart failure but no current symptoms.
MadridAges 65 years+ - NCT07030920RecruitingPhase 2
Reducing inflammation in people living with HIV
This trial tests if a drug can lower inflammation in people with HIV who are on effective treatment. It may help reduce the risk of heart disease and other problems related to chronic inflammation.
Montreal, QuebecAges 18 years+ - NCT06907862Recruiting
SWITCH trial: swapping processed soy foods in a heart-healthy diet
This study tests whether swapping highly processed soy foods for less processed soy foods, as part of a heart-healthy diet, can improve blood pressure, blood sugar, and weight in adults with obesity and high blood pressure. It may be a good option if you have type 2 diabetes and are already on stable medications.
Toronto, OntarioAges 18 years+ - NCT04101188Recruiting
Study how extra potassium affects blood vessels
This study looks at how eating more potassium may protect blood vessels in healthy people. You may be eligible if you have normal blood pressure and a normal heart rhythm test, and you do not have certain health conditions.
Newark, DelawareAges 18–45 - NCT03480633Recruiting
Heart failure precision medicine registry
This registry collects health and heart-related information to better understand heart failure (with preserved or reduced pumping strength) and guide more precise care. You may be asked to share tests and results, and help researchers learn which patterns match different types of heart failure.
Boston, MassachusettsAges 18 years+ - NCT03264352RecruitingPhase 4
Treatment for slightly high blood pressure in type 2 diabetes
This trial tests an intervention to help adults with type 2 diabetes who have “high-normal” blood pressure (not severely high). If you qualify, you may learn whether this approach improves blood pressure and related health outcomes over time.
Guangzhou, GuangdongAges 45–79 - NCT02016430Recruiting
Diet study to lower TMAO levels using gut microbes
This trial looks at whether a structured 12-week diet can lower a blood chemical called TMAO, which is linked to heart and kidney risk for some people. It may help you see if diet changes can shift gut microbes and reduce TMAO-related signals.
Cleveland, OhioAges 18 years+ - NCT07393412Recruiting
Heart and vessel disease study for Korean patients at Samsung Medical Center
This study looks at people who have visited Samsung Medical Center for heart or blood vessel problems. It aims to find what factors affect their health over time, which could help doctors predict and prevent future issues.
SeoulAges Any age - NCT04263038RecruitingPhase 4
Watchful waiting versus blood thinners for small lung clots
This trial compares close monitoring (“watch and wait”) versus taking the blood thinner rivaroxaban in people with a small type of lung blood clot. It aims to find out whether low-risk patients can safely avoid or reduce anticoagulation while still staying healthy.
Woluwe-Saint-Lambert, Brussels CapitalAges 18 years+ - NCT06324981Recruiting
AI text messages to help your heart health
This study tests if text messages from an AI program can help you improve your heart health habits, like taking medication on time and managing blood pressure, cholesterol, or diabetes.
Denver, ColoradoAges 18–89 - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
La Jolla, CaliforniaAges 45–80
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Common questions
- Are there clinical trials for cardiovascular disease risk factor?
- Yes. Clin2 currently lists 159 recruiting cardiovascular disease risk factor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk factor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk factor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.