Clinical trials
Chemoradiation clinical trials
Below are recruiting chemoradiation clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03712774Recruiting
Study of how chemoradiation affects quality of life
This observational study follows people with esophageal cancer to see how their quality of life changes after chemoradiation. It does not change your treatment, but it may help doctors better understand what to expect during and after therapy.
Munich, BavariaAges 18 years+ - NCT03792854Recruiting
Quality-of-life study after standard treatment for anal cancer
This observational study follows people with anal cancer to understand how their quality of life changes after they receive standard chemoradiation therapy. It may help doctors better support patients with symptoms, recovery, and daily functioning over time.
Munich, BavariaAges 18 years+ - NCT03731130Recruiting
Study on quality of life after rectal cancer treatment and surgery
This observational study follows people with rectal cancer who get radiation (with or without chemotherapy) before surgery. It aims to understand how these treatments affect quality of life after surgery.
Munich, BavariaAges 18 years+ - NCT04135664RecruitingPhase 3
Compare surgery vs chemoradiation for early throat cancer
This study compares two ways to treat a type of esophagus cancer: surgical removal (esophagectomy) versus chemoradiation (chemo plus radiation). It is for people with early-stage findings where scans suggest no lymph node spread.
Nanchang, JiangxiAges 18–75 - NCT04974346RecruitingPhase 3
Radiation to prevent spread in cervical cancer lymph nodes
This Phase 3 trial tests whether adding a preventive radiation treatment to lymph node areas near the abdomen helps stop cervical cancer from spreading. It aims to improve outcomes for people with certain cervical cancer stages and lymph node results on PET-CT.
Hangzhou, ZhejiangAges 18–75 - NCT05367206RecruitingPhase 3
Tested chemotherapy before chemoradiation for advanced cervical cancer
This trial compares two treatment plans for stage IIIC cervical cancer: giving chemotherapy first, then chemoradiation, versus going straight to chemoradiation. It may help doctors see which approach works better for shrinking the cancer before and during radiation.
Guangzhou, GuangdoneAges 18–70 - NCT05378087Recruiting
Compare two ways to plan treatment for cervical cancer
This study compares two staging methods—using surgery results versus imaging tests—to help doctors plan treatment for locally advanced cervical cancer. It may improve how accurately the cancer is mapped, which could affect treatment choices and outcomes.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05492123RecruitingPhase 2
Nivolumab plus ipilimumab with chemoradiation for cervical cancer
This Phase 2 study tests whether adding immunotherapy (nivolumab and ipilimumab) to standard chemoradiation can improve treatment for cervical cancer. It may help by training the immune system to better target cancer cells while radiation and chemotherapy work in the body.
Fortaleza, CearáAges 18–95 - NCT05245474RecruitingPhase 2
Before-surgery chemoradiation plus PD-1 for locally advanced rectal cancer
This trial studies giving long-course radiation and chemotherapy before surgery, plus an immunotherapy medicine (PD-1) to help the tumor shrink more. It’s for people with stage II or III rectal cancer that has not spread to distant organs.
Beijing, Beijing MunicipalityAges 18–75 - NCT05905315RecruitingPhase 2
Vulvar cancer treatment: chemoradiation vs chemotherapy then surgery
This Phase 2 trial compares two treatment approaches for some women with vulvar squamous cell cancer: chemoradiation first, or chemotherapy first followed by surgery. The goal is to see which strategy works better or is safer for tumors that are hard to remove without major pelvic surgery.
AmsterdamAges 18 years+ - NCT03465982Recruiting
Timing surgery after chemotherapy and radiation for rectal cancer
This trial studies the best time to do surgery after you finish chemotherapy and radiation for rectal cancer. It may help improve how well minimally invasive surgery works and how safely it can be done.
Alessandria, ALAges 18 years+ - NCT07625943Recruiting
Faster Radiation Treatment for Cervical Cancer
This trial tests a new way of giving radiation therapy for cervical cancer that uses higher doses in fewer treatments. Researchers want to see if this faster approach works as well as standard radiation while reducing side effects and treatment time.
New Delhi, New DelhiAges 18–65 - NCT07061977RecruitingPhase 3
New cancer drug combo for advanced cervical cancer
This trial tests if giving the immunotherapy drug pembrolizumab before and after standard chemoradiation works better than the standard approach for people with high-risk cervical cancer that has spread locally.
Birmingham, AlabamaAges 18 years+ - NCT06997913Enrolling by invitation
Immunotherapy and chemoradiation after bile duct cancer surgery
This trial tests whether combining immunotherapy with chemotherapy and radiation after surgery can help prevent bile duct cancer from coming back in people who have a high risk of recurrence.
XiAn, ShanxiAges 18–70 - NCT06592599RecruitingPhase 2
Drug combo for EBV-related nasopharyngeal cancer
This trial tests a combination of three drugs (gemcitabine, docetaxel, and toripalimab) as a first treatment for a type of nasopharyngeal cancer linked to the Epstein-Barr virus. The goal is to see if this combination helps shrink tumors before other treatments like radiation.
Palo Alto, CaliforniaAges 18 years+ - NCT04555226Recruiting
Lymph node surgery for advanced cervical cancer
This trial studies whether removing lymph nodes during surgery helps people with stage IIICr cervical cancer. It looks at outcomes and may help guide better treatment for lymph node spread.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06181656Recruiting
Pneumonia Vaccine Study for Esophageal and Liver Cancer Patients
This trial studies how well the pneumonia vaccine works in people with esophageal or liver cancer who have low white blood cell counts after chemoradiation. It aims to see if the vaccine can still protect them from infection.
Houston, TexasAges 18 years+ - NCT04178174RecruitingPhase 3
Boost radiation for HPV throat cancer with shorter treatment
This trial studies whether adding a precise “extra boost” to radiation can work as well as (or better than) standard radiation for HPV-related oropharynx cancer, while keeping the overall treatment shorter. It may help improve tumor control while aiming for manageable side effects.
London, OntarioAges 18 years+ - NCT03051464RecruitingPhase 2/Phase 3
Testing two ways to boost radiation to prevent rectal surgery
This study looks at whether two different added “boosts” of radiation can work as well for rectal cancer patients, aiming to avoid or reduce the need for rectal cancer surgery. You would receive a specific combination of radiation (including brachytherapy) and chemotherapy, and your tumor’s location and size will determine if you can take part.
Dallas, TexasAges 18–80 - NCT03249519Recruiting
Radiation plus heat for advanced cervical cancer
This trial studies whether adding controlled heat (“hyperthermia”) to radiation therapy (or radiation with chemotherapy) can improve outcomes in advanced cervical cancer. It focuses on people who can safely receive intensive pelvic radiation and heat treatment.
ErlangenAges 18 years+ - NCT03731442RecruitingPhase 3
Radiation plus chemotherapy for esophageal cancer that came back
This Phase 3 trial studies giving combined chemotherapy and radiation to treat esophageal cancer that has returned after earlier surgery and/or prior treatments. It may help control the cancer in the area where it comes back, especially when the surgical margins were not fully clear or the cancer is outside the original radiation field.
Beijing, Beijing MunicipalityAges 16–70 - NCT04951635RecruitingPhase 3
Almonertinib after chemoradiation for stage III lung cancer
This Phase 3 trial tests whether almonertinib given after standard chemoradiation can help people with stage III, non-surgical lung cancer live longer and/or control the cancer. It is for tumors with specific EGFR mutations linked to sensitivity to EGFR-targeted medicines.
Ji'nan, ShandongAges 18 years+ - NCT04138212RecruitingPhase 3
Chemo alone vs chemo with radiation before esophagus surgery
This study compares chemotherapy alone versus chemotherapy plus radiation given before surgery for locally advanced esophagus squamous cell cancer. The goal is to see which treatment helps more people have a successful operation and better cancer control.
Zhengzhou, HenanAges 18–70 - NCT05628922RecruitingPhase 2
Blood EBV DNA–guided therapy for advanced nasopharyngeal cancer
This trial tests a treatment approach for people with locally advanced nasopharyngeal cancer using their blood EBV DNA level (a cancer-related virus marker). It may help doctors choose and adjust therapy based on how much of this marker is in your blood after standard treatment.
Shanghai, Shanghai MunicipalityAges 18–70
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Common questions
- Are there clinical trials for chemoradiation?
- Yes. Clin2 currently lists 95 recruiting chemoradiation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemoradiation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemoradiation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.