Clinical trials
Chronic Back Pain clinical trials
Below are recruiting chronic back pain clinical trials, each written for real people, not researchers. We’re tracking 329 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT06861920RecruitingPhase 4
NSAID use for painful periods to prevent chronic pelvic pain
This study tests whether using NSAIDs (like naproxen) for painful periods can help prevent chronic pelvic pain later on. It's for people with regular, painful periods who are otherwise healthy.
Evanston, IllinoisAges 18–35 - NCT06756516Recruiting
Feldenkrais Method for balance and back pain relief
This trial tests if the Feldenkrais Method, a gentle movement therapy, can improve balance and reduce pain in people with long-term mechanical back pain. It may be a good option if you've had back pain for at least 6 months and it doesn't shoot past your knee.
GizaAges 18–45 - NCT07334561Recruiting
Brain stimulation for depression and pain
This study tests a non-invasive brain stimulation treatment (transcranial electrical stimulation) for people who have both depression and chronic pain. It aims to see if this treatment can help improve mood and reduce pain.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT07195422Recruiting
Study of a new device for low back pain relief
This trial tests a wearable device called Japet.W+ to see if it can help reduce chronic low back pain. It might be an option for people who have had lower back pain for a long time and are looking for non-surgical relief.
Clermont-FerrandAges 18–80 - NCT07038434Recruiting
Using artificial intelligence to measure pain in chronic pain patients
This study uses artificial intelligence to better understand and measure pain in people with chronic pain. The goal is to develop smarter ways to assess pain automatically, which could lead to better treatment.
Salerno, ItalyAges 18 years+ - NCT07009158RecruitingPhase 1/Phase 2
Ketamine plus therapy for pain and PTSD
This trial tests if ketamine combined with talk therapy helps people with both chronic pain and PTSD. Participants receive ketamine through an IV in group therapy sessions over several weeks, with the goal of reducing pain and PTSD symptoms.
Kingston, OntarioAges 18–64 - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Chicago, IllinoisAges 18 years+ - NCT06983678Recruiting
Quitting smoking and pain sensitivity study
This study looks at how quitting smoking affects pain sensitivity in people who smoke, especially those with chronic low back pain. Researchers will use brain scans and daily surveys to understand these changes.
Durham, North CarolinaAges 21–65 - NCT06873386Recruiting
Electrical stimulation for glute weakness after back pain
This study tests a non-surgical treatment using a small needle to send gentle electrical pulses to the glute (buttock) muscles. It is for people who have had low back pain in the past and now have weak glute muscles.
Sabadell, BarcelonaAges 18 years+ - NCT06083597Enrolling by invitation
Developing a pelvic pain questionnaire for women
This study aims to develop a new questionnaire to better understand and measure chronic pelvic pain in women, especially when it's linked to enlarged pelvic veins. You will be asked to take part in interviews and fill out surveys to help create a tool that reflects your experience.
New York, New YorkAges 18–60 - NCT05422040Recruiting
Dry needling or tecartherapy for long-term low back pain
This study compares two physical therapies—dry needling versus tecartherapy—to see which helps people with long-lasting, non-specific low back pain. You may be eligible if your pain has lasted more than 6 weeks and is not caused by nerve or serious underlying conditions.
Alcalá de Henares, MadridAges 18–65 - NCT04824248Recruiting
Weight-loss program for chronic low back pain
This trial studies whether weight loss can improve long-lasting, non-specific low back pain. It may help people whose back pain is partly related to extra weight by testing a structured approach over time.
BrusselsAges 18–65 - NCT07163117Recruiting
Back exercises for female university students with back pain
This study tests two different types of back exercises to see which works better for reducing mechanical low back pain (pain not caused by injury or disease) in female university students. It may help you find a good exercise routine if you have had this type of back pain for a while.
CairoAges 18–24 - NCT06661850Recruiting
New imaging test to guide lower back surgery decisions
This study tests a new imaging tool called Nociscan to see if it helps doctors decide who will benefit from lumbar spine surgery for low back pain. It may help predict surgical outcomes and guide treatment.
Phoenix, ArizonaAges 18–70 - NCT03912519Enrolling by invitation
Testing two ways to numb lumbar back pain with radiofrequency
This study compares two needle-based techniques to treat long-lasting low back pain by stopping overactive pain signals from specific back joints. If you’ve already tried physical therapy and pain medicines without enough relief, this trial may test which technique works better for pain reduction.
Nashville, TennesseeAges 40 years+ - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT07724847Recruiting
Validating new criteria for diagnosing axial spondyloarthritis
This study aims to confirm new classification criteria for axial spondyloarthritis, a type of inflammatory arthritis affecting the spine and sacroiliac joints. Participants with chronic back pain lasting at least 3 months and starting before age 45 will undergo a series of tests to see if these new criteria better identify the condition.
Beijing, Beijing MunicipalityAges 18–45 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT07094282Recruiting
Integrative therapies study for chronic back or neck pain
This study is testing integrative medicine therapies for chronic back or neck pain. It is for military members and their families who receive care at Nellis Air Force Base. The goal is to see if these therapies can help reduce pain and improve quality of life.
Nellis Air Force Base, NevadaAges 18 years+ - NCT06641102Recruiting
Healing track for chronic back pain
This trial tests a non-drug, talk-based therapy approach for chronic back pain. It may help you manage pain without medication, and all study activities can be done from home using your smartphone.
New York, New YorkAges 21–70 - NCT05657964Recruiting
Study of a back pain exercise program for chronic low back pain
This trial tests whether a structured exercise/education program can help people with chronic lower back pain. You may qualify if your pain and disability scores are high enough and you can complete study activities in English.
Redwood City, CaliforniaAges 18–65 - NCT07709416Recruiting
Testing toludesvenlafaxine for long-lasting low back pain
This study tests an experimental medication called toludesvenlafaxine to see if it can help people with long-lasting low back pain that has no clear cause. If you have moderate to severe lower back pain for more than 3 months and haven't taken antidepressants before, this may be an option for you to explore.
BeijingAges 18–75
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Common questions
- Are there clinical trials for chronic back pain?
- Yes. Clin2 currently lists 329 recruiting chronic back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.