Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 397 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06795763Enrolling by invitation
New imaging & catheter system for blocked heart arteries
This trial tests a new imaging and catheter system to treat chronic total blockages in heart arteries. If you still have chest pain or other symptoms despite medical therapy, this study may help open the blockage and improve blood flow.
Atlanta, GeorgiaAges 18 years+ - NCT06337812Recruiting
Fiber supplement study for heart failure and diabetes
This study tests whether adding a daily fiber supplement can improve health in people with heart failure and type 2 diabetes. Participants take the supplement for several weeks to see if it helps manage symptoms and blood sugar.
Ann Arbor, MichiganAges 18 years+ - NCT06518694RecruitingPhase 3
Can you stop beta-blockers after heart failure recovery?
This trial tests whether people whose heart function has returned to normal after heart failure can safely stop taking beta-blockers. It aims to see if staying on the medication is still needed or if stopping is just as safe.
Paris, IDFAges 18 years+ - NCT06837766Recruiting
Blood filtering for severe liver failure with organ damage
This study tests a blood-filtering system called CytoSorb in people with severe liver failure that also affects other organs. It aims to see if removing toxins from the blood can help reduce damage and improve recovery.
Ancona, AnconaAges 18 years+ - NCT03549754Recruiting
iCaReMe registry for adults with diabetes, blood pressure, or heart/kidney disease
This is a health “registry,” meaning it collects information about people living with common chronic conditions. It may help researchers better understand real-world health needs and outcomes for people with type 2 diabetes, high blood pressure, heart failure, and/or chronic kidney disease.
Fortaleza, CearáAges 18 years+ - NCT07052539Recruiting
Kidney disease in heart failure with obesity
This study looks at how kidney disease relates to a type of heart failure (called HFpEF) that often happens in people with obesity. It will help doctors understand this connection better.
Jackson, MississippiAges 18–75 - NCT07237451Recruiting
Heart and kidney study of SGLT2 inhibitors
This study looks at whether a type of diabetes medicine called SGLT2 inhibitors (also known as flozins) can help protect the heart and kidneys in people with both heart failure with preserved pumping function and moderate chronic kidney disease, with or without diabetes.
IașiAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT07518446Recruiting
Health Screening for Adults Starting Psychiatric Care
This study checks the physical health of adults beginning treatment for serious mental illnesses like schizophrenia or depression at two Danish clinics. It aims to catch health problems early that people with these conditions often experience.
CopenhagenAges 18 years+ - NCT03836482Recruiting
SCD test for people with heart and kidney failure awaiting LVAD
This study looks at whether a treatment called SCD is safe and workable in people who have worsening heart failure along with kidney problems, and who are waiting to get an LVAD (a mechanical heart pump). It is mainly a feasibility study, meaning the researchers want to see if this approach can be used in real hospital care and monitor effects on key health measures.
Ann Arbor, MichiganAges 18 years+ - NCT07753681Recruiting
Chronic disease care in Zambia
This study helps improve care for people with long-term illnesses like diabetes or high blood pressure in Zambia. It aims to make sure you get regular check-ups and support.
Lusaka, Lusaka ProvinceAges Any age - NCT07234422RecruitingPhase 3
Selenium and CoQ10 for heart failure
This study tests whether adding selenium and CoQ10 (two natural supplements) to standard heart failure treatment helps people with chronic heart failure feel better and improve their health. Researchers are using a registry-based approach to track participants in the Netherlands.
AlkmaarAges 18 years+ - NCT06154044RecruitingPhase 2
Cell therapy for heart recovery with LVAD support
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
LjubljanaAges 18–65 - NCT06447467Recruiting
Heart failure recovery in diabetics and non-diabetics
This study looks at how people with and without diabetes recover from acute heart failure (a sudden worsening). It aims to compare short-term outcomes in the hospital.
SohagAges 18 years+ - NCT06183437RecruitingPhase 4
Can I stop heart meds after cancer therapy?
This trial tests whether it is safe to stop taking heart failure medications in people who developed heart weakness after cancer treatment but whose heart function has since recovered. It aims to see if stopping these drugs leads to any worsening of heart health.
Los Angeles, CaliforniaAges 18 years+ - NCT06916585RecruitingPhase 2
Testing AS1501 for acute-on-chronic liver failure
This trial tests a new drug called AS1501 for people with acute-on-chronic liver failure (a sudden worsening of chronic liver disease). It aims to see if the drug can help improve liver function and reduce the need for a liver transplant. You may be eligible if you are in the early or middle stage of this condition and have a specific blood marker (high TRAIL level).
Shenzhen, GuangdongAges 18–75 - NCT06652776Enrolling by invitation
Italian COPD patient registry study
This study is creating a registry to better understand Chronic Obstructive Pulmonary Disease (COPD) in Italian patients. It will collect information from people with COPD to improve care and research.
Milan, MilanAges 40 years+ - NCT04343430Recruiting
Hospital study for fluid buildup in heart failure with preserved heart function
This study looks at how well doctors can assess fluid buildup before you leave the hospital if you have a type of heart failure called “preserved ejection fraction.” It may help improve decisions about when and how safely people are discharged.
Vandœuvre-lès-NancyAges 18 years+ - NCT04343443Recruiting
Test whether a lung ultrasound helps discharge planning after heart failure
This study looks at people hospitalized for worsening heart failure with weaker pumping (reduced ejection fraction). It tests whether a lung ultrasound evaluation near discharge can improve how doctors decide it is safe to send you home.
Vandœuvre-lès-NancyAges 18 years+ - NCT07449377Recruiting
Can a liver scan help diagnose heart failure in the ER?
This study tests whether a quick, non-invasive liver scan (Fibroscan) can help diagnose heart failure in people who come to the emergency department with sudden shortness of breath.
ParisAges 18 years+ - NCT07492524Recruiting
Better care for older adults with AF and heart failure in rural China
This trial tests a new way to manage care for older patients with atrial fibrillation and heart failure living in rural areas. It uses village doctors and telemedicine to help monitor and treat these conditions together.
Yancheng, DongtaiAges 65–80 - NCT06435156RecruitingPhase 2
Sotagliflozin for Heart Failure in Type 1 Diabetes
This trial tests a medication called sotagliflozin for people who have both type 1 diabetes and heart failure symptoms. The goal is to see if it can improve how you feel and manage your heart and diabetes.
AberdeenAges 18–84 - NCT07318103RecruitingPhase 2
Study of HRS-9057 for fluid retention in heart failure
This trial tests an investigational drug, HRS-9057, in people hospitalized with heart failure who still have fluid buildup despite taking standard diuretics. The goal is to see if HRS-9057 helps remove excess fluid better than current treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05001009Enrolling by invitation
Goals of care conversation support for certain serious illnesses
This study helps primary care clinicians and their patients have structured “goals of care” conversations (about what matters most and care preferences). It may help you get clearer, earlier planning—especially if you have a serious illness and higher risk of hospitalization or death.
Palo Alto, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 397 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.