Clinical trials
Chronic Heart Failure clinical trials
Below are recruiting chronic heart failure clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06249932RecruitingPhase 4
Empagliflozin for heart failure and end-stage kidney disease
This trial tests whether empagliflozin, a medication for heart failure, can help people who also have end-stage kidney disease and are on dialysis. It aims to see if the drug improves heart function in this group.
Hsinchu, TaiwanAges 20 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+ - NCT05194111RecruitingPhase 1/Phase 2
Heart medication study for cancer survivors with mild heart weakness
This study tests a heart medication (sacubitril/valsartan) in young cancer survivors whose hearts were weakened by anthracycline chemotherapy but are not yet having heart failure symptoms. It aims to see if the drug can improve heart function and prevent future problems.
Richmond, VirginiaAges 18–120 - NCT07391683Recruiting
Heart failure support before heart surgery
This trial tests if special remote care before heart surgery can improve recovery for people with heart failure. You will have regular check-ins by video or phone to help manage your health before your operation.
Innsbruck, TyrolAges 18 years+ - NCT06702501Recruiting
Shunt device to treat heart failure with preserved ejection fraction
This trial tests a tiny tube (shunt) placed in the heart to relieve pressure and ease severe shortness of breath. It's for people with a type of heart failure where the heart pumps well but doesn't relax enough.
Rochester, MinnesotaAges 30 years+ - NCT06898515RecruitingPhase 3
Fluid removal study for acute heart failure patients
This trial tests a device designed to safely remove extra fluid from patients hospitalized with worsening heart failure. It may help those who are not responding well to standard water pills (diuretics).
Irvine, CaliforniaAges 22 years+ - NCT07076329Recruiting
Using a special diet to prevent malnutrition in older heart patients
This trial tests whether a special type of food can help prevent malnutrition in older adults with heart failure or atrial fibrillation. It looks at how the bacteria in your gut and inflammation in your body affect your brain and overall health.
FlorenceAges 70 years+ - NCT07265986Recruiting
Comparing robotic remote heart ultrasound to standard care for heart failure
This trial tests whether a robot that performs heart ultrasounds from a distance works as well as a standard in-person ultrasound for managing heart failure. It could help people on the island of Marie-Galante get specialist care without traveling.
Grand-BourgAges 18 years+ - NCT05919342Recruiting
Screening for early heart failure in primary care or at home
This trial tests whether simple screening using a blood test (natriuretic peptides) plus an ultrasound of the heart (echocardiogram) can find early heart failure sooner. Finding it earlier may help doctors start the right management to prevent it from getting worse.
Cleveland, OhioAges 40 years+ - NCT06107907Recruiting
Oxygen flow and pressure in heart failure patients
This study tests a new way to measure pressure in your lungs while you receive high-flow oxygen therapy. It may help doctors better understand how to use this treatment in people with heart failure who need extra breathing support.
TaipeiAges 18 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06910475Enrolling by invitation
Exercise and biomarker study to reduce toxins in kidney disease
This study tests whether a supervised exercise program can help reduce toxins in the blood for people with chronic kidney disease and metabolic syndrome. Researchers will also look at blood markers to understand how exercise affects the body.
Taguatinga, Federal DistrictAges 18 years+ - NCT05933083Recruiting
In-person vs telehealth heart rehab comparison study
This study compares whether heart rehabilitation done in person or by telehealth (video/phone) works as well for people with certain heart conditions. It may help you and others choose the safest and most effective way to receive cardiac rehab.
San Francisco, CaliforniaAges 18 years+ - NCT05285878Enrolling by invitationPhase 2
Fingolimod to protect kidney function after kidney transplant
This trial tests whether fingolimod can reduce kidney scarring and preserve kidney function after a new kidney transplant. It focuses on people who are in the early period after transplant who may be at risk for scarring in the kidney.
Houston, TexasAges 18–65 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT05490901Recruiting
Test exercise heart pressure measurements with an ultrasound
This study looks at how well two heart tests taken during exercise—direct heart pressure measurement and an ultrasound—can explain shortness of breath with activity. It may help doctors better diagnose what’s causing your symptoms.
SeoulAges 19 years+ - NCT06897410Recruiting
Support program after hospital discharge for heart or lung issues
This program offers extra support—like social and home care help—after you leave the hospital for a heart or lung problem. It's designed for people 65 and older who live in the Sant Jaume de Calella Hospital area.
Calella, BarcelonaAges 65 years+ - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT07083557Recruiting
Validation study for lab tests on hormones and metabolism
This study checks if lab tests used for hormone, heart, metabolism, and muscle disorders are accurate and reliable. You might be eligible if you are an adult with a body mass index between 16 and 60.
Columbia, MissouriAges 18–100 - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT05895136RecruitingPhase 2
Albumin plus blood thinner for severe cirrhosis after hospital recovery
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
ClichyAges 18–80 - NCT03383419RecruitingPhase 2
Hepatitis C–safe antiviral plan for heart transplant recipients
This Phase 2 trial tests giving newer hepatitis C medicines in a careful way to people getting a heart transplant who currently do not have hepatitis C in their blood. The goal is to lower hepatitis C infection risk from donated organs while keeping transplant outcomes safe.
Los Angeles, CaliforniaAges 18–90 - NCT07192211RecruitingPhase 2
Study of ADR-002K for Heart Failure Patients Having Bypass Surgery
This study tests an experimental drug (ADR-002K) for people with heart failure caused by blocked arteries who are about to have bypass surgery. The goal is to see if it helps the heart recover better after surgery.
Osaka, SuitaAges 18–80
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Common questions
- Are there clinical trials for chronic heart failure?
- Yes. Clin2 currently lists 396 recruiting chronic heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.