Clinical trials
Chronic Kidney Disease (Stages 4 and 5) clinical trials
Below are recruiting chronic kidney disease (stages 4 and 5) clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06224153Recruiting
Tracking Protein Intake in Advanced Kidney Disease
This study compares two ways to track how much protein you eat using a mobile app or website. It is for people with advanced chronic kidney disease who are already in a nutrition program and want to follow a low-protein diet.
Marseille, FranceAges 18 years+ - NCT07694791Recruiting
Gut health supplements for people on peritoneal dialysis
This trial tests whether taking probiotic and prebiotic supplements can improve gut health in people receiving peritoneal dialysis at home. It may help with digestion and overall well-being.
Monterrey, Nuevo LeónAges 18 years+ - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT06463483Recruiting
Automated Insulin Delivery for People with Advanced Kidney Disease
This trial tests an automated insulin pump system for people with diabetes who also have advanced kidney disease. It may help manage blood sugar more easily.
LondonAges 18–70 - NCT06542016Recruiting
Heart risk prediction in dialysis patients using a questionnaire
This study looks at how a simple questionnaire (called KCCQ) about your heart health and quality of life can help predict future heart risks for people on dialysis. Researchers want to see if your answers to this questionnaire can help doctors take better care of you.
Guangdong, GuangdongAges 18 years+ - NCT06660277Recruiting
Dialysis with expanded solute removal study
This trial tests a special dialysis filter (Elisio HX) that removes more waste products from the blood. It aims to see if this approach improves health outcomes for people on regular in-center hemodialysis.
London, OntarioAges 45 years+ - NCT07613593Recruiting
Digital kidney disease care platform evaluation study
This study evaluates whether MyRenalCare, a digital platform that helps patients with chronic kidney disease (CKD) monitor and manage their condition, improves health outcomes and patient experience. Researchers will compare people using the platform with those receiving standard care, and interview patients and staff about their experiences.
Portsmouth, HampshireAges 18 years+ - NCT06725810RecruitingPhase 4
Enarodustat for anemia in chronic kidney disease (not on dialysis)
This trial tests enarodustat, a pill for anemia, in people with chronic kidney disease who are not on dialysis. It aims to see if it can safely raise hemoglobin levels.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06799936Recruiting
Helping older kidney patients decide on treatment with their doctor
This trial tests a program that helps older adults with advanced kidney disease talk with their doctors about treatment options. The goal is to improve shared decision-making before they need dialysis or a transplant.
Hong KongAges 65 years+ - NCT06897605RecruitingPhase 2
Dapagliflozin for anemia in kidney disease
This trial tests whether a medication called dapagliflozin can help improve anemia in people with chronic kidney disease. If you have moderate to severe kidney disease and low red blood cell counts despite taking standard anemia treatment, this study may explore a new option.
Al MansurahAges 18 years+ - NCT06971874Recruiting
Sleep apnea and kidney disease: A study on outcomes
This trial looks at how obstructive sleep apnea affects people with chronic kidney disease (stages 3-4). It aims to help understand the connection between these conditions and guide better care.
Guangzhou, GuangdongAges 18–75 - NCT06982079RecruitingPhase 3
SGLT2 inhibitors for advanced kidney disease
This trial tests whether SGLT2 inhibitor drugs can protect kidney function in people with advanced chronic kidney disease who are not yet on dialysis. It may help slow further kidney decline.
CairoAges 18 years+ - NCT07017270RecruitingPhase 4
GLP-1 drugs for people with diabetes on dialysis
This study tests if a type 2 diabetes medication called a GLP-1 receptor agonist (like Ozempic) is safe and effective for people on dialysis. It may help manage blood sugar and improve health outcomes for those with kidney failure.
Toronto, OntarioAges 18 years+ - NCT07107919Recruiting
Imaging heart and kidney health in chronic kidney disease
This study uses advanced imaging (PET/MRI) to look at how kidney disease affects the heart and blood vessels. It may help doctors better understand and treat chronic kidney disease.
Qingdao, ShandongAges 18–80 - NCT07123909Recruiting
Immune adsorbent therapy for dialysis patients with inflammation
This study tests a therapy that absorbs inflammatory substances from the blood during dialysis. It may help people on dialysis who have ongoing inflammation, shown by high IL-6 or CRP levels.
MoscowAges 18 years+ - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Dothan, AlabamaAges 18–80 - NCT07186218Recruiting
Symptom monitoring with feedback for advanced kidney disease
This study tests a symptom-monitoring system with feedback for people with advanced chronic kidney disease (CKD). The goal is to help manage symptoms and improve quality of life without needing dialysis or a transplant right away.
Boston, MassachusettsAges 18 years+ - NCT07187713RecruitingPhase 4
Study of ACE Reno, Pico Cell Matrix for kidney health
This trial tests a new treatment called ACE Reno, Pico Cell Matrix to see if it can improve kidney function in people with chronic kidney disease (CKD) at various stages. It may be an option if you have early to moderate kidney issues (including after a transplant) and are already on standard therapies.
Giza, GZAges 18–80 - NCT06741072RecruitingPhase 1
Vaccine to prevent EBV-related cancer in transplant patients
This trial tests a vaccine (OSU-2131) that may help prevent cancers caused by the Epstein-Barr virus in people waiting for an organ transplant. The vaccine is designed to train your immune system to fight the virus.
Columbus, OhioAges 18–65 - NCT07358572Recruiting
Eye-brain-kidney study in chronic kidney disease
This study is looking at how chronic kidney disease (CKD) affects the eyes, brain, and kidneys. It uses MRI scans to examine these organs, and aims to find connections that could help improve care for people with CKD.
Beijing, Beijing MunicipalityAges 18–70 - NCT07374042RecruitingPhase 3
A supplement to protect muscle in advanced kidney disease
This trial tests whether a special diet supplement (Ketoanalogue) can help protect your muscles while you follow a moderate protein diet. It is for people with chronic kidney disease stage 4 or 5 who are not on dialysis or have not had a kidney transplant.
Clermont-FerrandAges 18–100 - NCT07385651Recruiting
Cool storage for donated kidneys
This trial compares storing donated kidneys at 10 degrees Celsius (a cooler temperature) instead of the usual ice storage. It tests if this might help the kidney stay healthier before transplant.
Nashville, TennesseeAges 18 years+ - NCT07446296Recruiting
Kidney transplant exercise program for older adults
This trial tests whether a special exercise program can help people on the kidney transplant waiting list get stronger and improve their health. You would use an app to follow exercise routines at home and check in with the research team.
Philadelphia, PennsylvaniaAges 60 years+ - NCT07483372RecruitingPhase 1
SC101 injection for resistant hypertension with kidney disease
This early-phase trial tests an injection called SC101 into the fat around your kidney. It aims to help lower blood pressure in people whose hypertension is poorly controlled despite multiple medications and who have moderate to severe chronic kidney disease.
Suzhou, JiangsuAges 18–65
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Common questions
- Are there clinical trials for chronic kidney disease (stages 4 and 5)?
- Yes. Clin2 currently lists 112 recruiting chronic kidney disease (stages 4 and 5) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease (stages 4 and 5) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease (stages 4 and 5) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.