Clinical trials
Chronic Kidney Disease (Stages 4 and 5) clinical trials
Below are recruiting chronic kidney disease (stages 4 and 5) clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05944016RecruitingPhase 3
Dapagliflozin for early Alport kidney disease in teens and young adults
This trial tests dapagliflozin, a daily medicine, to slow kidney problems in people with early-stage chronic kidney disease caused by Alport syndrome. It may help protect kidney function and reduce worsening over time.
Heidelberg, Baden-WürttenbergAges 10–39 - NCT04522622RecruitingPhase 4
Teriparatide for low bone turnover in advanced kidney disease
This trial tests teriparatide (a hormone-like bone medicine) to improve bone health in people with advanced chronic kidney disease who are at risk for weak, low-turnover bone. It may help by changing how quickly your bones break down and rebuild.
AalborgAges 18–120 - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT05071131Recruiting
Inulin supplement to improve gut health in kidney disease
This trial studies whether taking inulin—a dietary fiber—can improve gut bacteria and the gut barrier in people with end-stage kidney disease on hemodialysis. It may help reduce gut-related problems that can affect overall health in kidney disease.
BerlinAges 18–75 - NCT07754097Recruiting
Tracking your health at home for chronic kidney disease
This study tests if regularly tracking your blood pressure, diet, and medications through a mobile app can help monitor kidney disease progression. It aims to see if this self-management approach helps you stay healthier.
Daejeon, DJAges 19–84 - NCT07741292RecruitingPhase 4
Kidney health study for older adults not on dialysis
This study tests whether a traditional Chinese medicine called Niaoduqing Granules can help improve kidney function in people over 60 with chronic kidney disease. It may offer a new way to manage the condition without dialysis.
Shanghai, Shanghai MunicipalityAges 61 years+ - NCT07741279Recruiting
Enarodustat for anemia in chronic kidney disease patients
This study tests a daily pill that helps people with chronic kidney disease and anemia make more red blood cells, which may reduce the need for other anemia treatments. It is for patients who are not on dialysis and do not plan to start dialysis or have a kidney transplant within the next six months.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT05679024RecruitingPhase 3
Apixaban to prevent stroke in atrial fibrillation and kidney failure
This trial tests apixaban (a blood thinner) to prevent stroke in people with atrial fibrillation or atrial flutter who have very poor kidney function or are on dialysis. If you qualify, you may help researchers find a safer way to lower stroke risk for this higher-risk group.
HelsinkiAges 18 years+ - NCT07694791Recruiting
Gut health supplements for people on peritoneal dialysis
This trial tests whether taking probiotic and prebiotic supplements can improve gut health in people receiving peritoneal dialysis at home. It may help with digestion and overall well-being.
Monterrey, Nuevo LeónAges 18 years+ - NCT06224153Recruiting
Tracking Protein Intake in Advanced Kidney Disease
This study compares two ways to track how much protein you eat using a mobile app or website. It is for people with advanced chronic kidney disease who are already in a nutrition program and want to follow a low-protein diet.
Marseille, FranceAges 18 years+ - NCT07613593Recruiting
Digital kidney disease care platform evaluation study
This study evaluates whether MyRenalCare, a digital platform that helps patients with chronic kidney disease (CKD) monitor and manage their condition, improves health outcomes and patient experience. Researchers will compare people using the platform with those receiving standard care, and interview patients and staff about their experiences.
Portsmouth, HampshireAges 18 years+ - NCT07592000RecruitingPhase 1/Phase 2
New Treatment for Type 1 Diabetes With Kidney Disease
This study tests a new experimental medication for people with type 1 diabetes who experience dangerous low blood sugar episodes and have early-stage kidney disease. The trial aims to help improve blood sugar control and reduce these risky episodes.
Miami, FloridaAges 18–70 - NCT06155604RecruitingPhase 2
SGLT2 inhibitor for lupus nephritis with kidney disease
This study tests if an SGLT2 inhibitor can help protect kidney function in people who have lupus nephritis (kidney inflammation caused by lupus) and chronic kidney disease (CKD). The goal is to see if this medicine can slow down further kidney damage.
Hong KongAges 18 years+ - NCT07544524Recruiting
Plant-Based Diet for Kidney Disease in Asian Adults
This study tests whether eating mostly plants (with some animal products) can safely help people with moderate kidney disease. Researchers will compare this diet to a standard kidney-friendly diet and see how it affects kidney function and overall health.
SingaporeAges 21–79 - NCT07494266Recruiting
Potassium in plant-based diet for kidney patients
This trial tests whether a plant-based diet with more potassium is safe for people with advanced chronic kidney disease (CKD) compared to a plant-based diet with less potassium. It may help you understand how to manage your potassium levels while eating more plants.
Huddinge, Stockholm LänAges 20–85 - NCT07487727RecruitingPhase 3
Study of an experimental anemia drug for chronic kidney disease patients not on dialysis
This trial tests an oral medication (AND017) for anemia caused by chronic kidney disease. It aims to improve red blood cell levels without needing dialysis or current anemia treatments.
Beijing, Beijing MunicipalityAges 18–75 - NCT07483372RecruitingPhase 1
SC101 injection for resistant hypertension with kidney disease
This early-phase trial tests an injection called SC101 into the fat around your kidney. It aims to help lower blood pressure in people whose hypertension is poorly controlled despite multiple medications and who have moderate to severe chronic kidney disease.
Suzhou, JiangsuAges 18–65 - NCT07446296Recruiting
Kidney transplant exercise program for older adults
This trial tests whether a special exercise program can help people on the kidney transplant waiting list get stronger and improve their health. You would use an app to follow exercise routines at home and check in with the research team.
Philadelphia, PennsylvaniaAges 60 years+ - NCT07444515Recruiting
Herbal medicine use in kidney disease patients
This study looks at how people with chronic kidney disease use herbal medicines (plants and natural remedies) on their own. It aims to understand what they take and why, which could help doctors give safer advice.
Saint-BenoîtAges 18 years+ - NCT07380113RecruitingPhase 4
Comparing two drugs for sleep in dialysis patients with itch
This trial tests if anrikefon or nalfurafine improves sleep quality in people on hemodialysis who have chronic kidney disease-related itching. It aims to find a better treatment for both itch and sleep problems.
Guangzhou, GuangdongAges 18–75 - NCT07385651Recruiting
Cool storage for donated kidneys
This trial compares storing donated kidneys at 10 degrees Celsius (a cooler temperature) instead of the usual ice storage. It tests if this might help the kidney stay healthier before transplant.
Nashville, TennesseeAges 18 years+ - NCT07374042RecruitingPhase 3
A supplement to protect muscle in advanced kidney disease
This trial tests whether a special diet supplement (Ketoanalogue) can help protect your muscles while you follow a moderate protein diet. It is for people with chronic kidney disease stage 4 or 5 who are not on dialysis or have not had a kidney transplant.
Clermont-FerrandAges 18–100 - NCT07358572Recruiting
Eye-brain-kidney study in chronic kidney disease
This study is looking at how chronic kidney disease (CKD) affects the eyes, brain, and kidneys. It uses MRI scans to examine these organs, and aims to find connections that could help improve care for people with CKD.
Beijing, Beijing MunicipalityAges 18–70 - NCT06897605RecruitingPhase 2
Dapagliflozin for anemia in kidney disease
This trial tests whether a medication called dapagliflozin can help improve anemia in people with chronic kidney disease. If you have moderate to severe kidney disease and low red blood cell counts despite taking standard anemia treatment, this study may explore a new option.
Al MansurahAges 18 years+
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Common questions
- Are there clinical trials for chronic kidney disease (stages 4 and 5)?
- Yes. Clin2 currently lists 112 recruiting chronic kidney disease (stages 4 and 5) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease (stages 4 and 5) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease (stages 4 and 5) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.